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Neuroradiology

The main characteristic of our group is its multidisciplinary nature, as it is comprised of neuroradiologists, technologists, and a physicist, engineer, and biochemist.

The main objectives of our projects are to gain knowledge about the pathophysiologic mechanisms implicated in several neurological diseases and to evaluate new biomarkers and therapies through the use of qualitative and quantitative magnetic resonance (MR) and computed tomography (CT) techniques, and by applying artificial intelligence tools to create prognostic models. Our focus is on the study of diseases such as multiple sclerosis, epilepsy, neuro-oncology, and stroke.

In addition, because of the experience we have acquired along the years in performing MR studies, we act as a platform for designing MR-based projects, processing images, and conducting quantitative data analysis.

Research lines

Quantitative analysis of MR images: image analysis and software development

This line is focused on the application of computer vision, image processing, pattern recognition, machine learning and fuzzy logic techniques to the analysis of MR images. Some areas of interest are the study of lesions, and iron quantification by means of advanced techniques such as QSM and SWI.

IP: Fco. Javier Aymerich Martínez, Juli Alonso Farre

Research in Cerebrovascular Diseases

This research line is mainly focused on the assessment of intracranial aneurysms. This includes the role of several imaging techniques to predict the risk of future rupture. Other interests are to associate imaging changes with the pathophysiological mechanisms that underlie aneurysm formation and to optimize the imaging protocol used in clinical practice.

IP: Alex Rovira Cañellas

Synthetic Imaging: Assessing its value in healthcare practice

The aim of the line is to evaluate synthetic MR images compared to conventional images to consider its use in healthcare protocols.

IP: Fco. Javier Aymerich Martínez, Juli Alonso Farre, Alex Rovira Cañellas

Publications

The role of gadolinium-based contrast agents in magnetic resonance imaging structured reporting and data systems (RADS).

PMID: 37702845
Journal: MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
Year: 2023
Reference: MAGMA. 2023 Sep 13. doi: 10.1007/s10334-023-01113-y.
Impact factor:
Publication type: Review in international publication
Authors: Clement, Olivier; Dekkers, Ilona A; Gianolio, Eliana; Karst, Uwe; Mallio, Carlo Augusto; Nederveen, Aart J; Parillo, Marco; Quattrocchi, Carlo Cosimo; Radbruch, Alexander; Rovira, Alex et al.
DOI: 10.1007/s10334-023-01113-y

MOG antibodies in adults with a first demyelinating event suggestive of multiple sclerosis.

PMID: 37705507
Journal: ANNALS OF NEUROLOGY
Year: 2023
Reference: Ann Neurol. 2023 Sep 14. doi: 10.1002/ana.26793.
Impact factor:
Publication type: Paper in international publication
Authors: Arrambide, Georgina; Auger, Cristina; Auger, Cristina; Bollo, Luca; Carbonell-Mirabent, Pere; Castillo, Joaquin; Castillo, Mireia; Cobo-Calvo, Alvaro; Cobo-Calvo, Alvaro; Comabella, Manuel et al.
DOI: 10.1002/ana.26793

Lysyl oxidase-dependent extracellular matrix crosslinking modulates calcification in atherosclerosis and aortic valve disease.

PMID: 37729730
Journal: BIOMEDICINE & PHARMACOTHERAPY
Year: 2023
Reference: Biomed Pharmacother. 2023 Sep 18;167:115469. doi: 10.1016/j.biopha.2023.115469.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso, Judith; Alonso, Judith; Ballester-Servera, Carme; Canes, Laia; Fernandez-Celis, Amaya; Lopez-Andres, Natalia; Martinez-Gonzalez, Jose; Puertas-Umbert, Lidia; Rodriguez, Cristina; Rodriguez-Sinovas, Antonio et al.
DOI: 10.1016/j.biopha.2023.115469

Association of magnetic resonance imaging phenotypes and serum biomarker levels with treatment response and long-term disease outcomes in multiple sclerosis patients.

PMID: 37754568
Journal: EUROPEAN JOURNAL OF NEUROLOGY
Year: 2023
Reference: Eur J Neurol. 2023 Sep 27. doi: 10.1111/ene.16077.
Impact factor:
Publication type: Paper in international publication
Authors: Castillo, Joaquin; Comabella, Manuel; Comabella, Manuel; Fissolo, Nicolas; Midaglia, Luciana; Miro, Berta; Montalban, Xavier; Rio, Jordi; Rio, Jordi; Rovira, Alex et al.
DOI: 10.1111/ene.16077

Blog

News

Els doctors Xavier Montalban, Àlex Rovira i Mar Tintoré han estat reconeguts en la categoria de Neurociències i Comportament, i el doctor Jordi Rello en la categoria Interdisciplinària.

The program, promoted by Biocat in collaboration with CIMIT (Boston), is aimed at entrepreneurs in the process of bringing their technology to market in the next few years.