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Neurovascular Diseases

Stroke is a medical emergency and one of the leading causes of death and disability worldwide. In this context, the Neurovascular Diseases Group was established in 2001, focusing on biomedical research into both ischemic and hemorrhagic stroke from a basic and translational perspective. Our work in this research field has covered the entire disease spectrum, from prevention and treatment to recovery. In 2017, we expanded our research interests to include vascular dementia and Alzheimer’s disease, related to the β-amyloid protein. Our ultimate goal as a research team is to help answer critical questions that will improve the clinical management of stroke and dementia, conditions with significant health impacts due to their high prevalence and associated disability. We are also committed to promoting scientific education among researchers and the society, and to fostering public engagement in these areas.

Since 2001, dozens of researchers have carried out their work in this laboratory, and as a team we have leaded translational and clinical projects through both preclinical studies with experimental models, as well as cohort studies in patients. The laboratory stands out for its extensive national and international collaborations, working closely with other research groups and the biomedical industry.

Our research focuses on identifying new therapeutic targets for cerebroprotection and brain repair, discovering diagnostic, prognostic, and recovery biomarkers in both biological fluids and neuroimaging, and investigating the mechanisms of neuronal and vascular damage. We also work in regenerative medicine and nanomedicine fields, with strong expertise in preclinical models of stroke, cerebral amyloidosis, and Alzheimer’s disease. More specifically, our main research lines are:

  • Neurovascular Protection and Repair in Stroke
  • Cerebral Amyloidosis
  • Clinical and Translational Research in Dementia

Team

Elisa Franchina

Elisa Franchina

Research technician
Neurovascular Diseases
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Itsasne De la Torre Sanchez

Itsasne De la Torre Sanchez

Predoctoral researcher
Neurovascular Diseases
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Laia Fernandez Resano

Laia Fernandez Resano

Main researcher
Neurovascular Diseases
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Liubovi Sopco

Liubovi Sopco

Predoctoral researcher
Neurovascular Diseases
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Marina Pérez González

Marina Pérez González

Predoctoral researcher
Neurovascular Diseases
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Marta Kinga Klimczak

Marta Kinga Klimczak

Predoctoral researcher
Neurovascular Diseases
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Elisa Franchina

Elisa Franchina

Research technician
Neurovascular Diseases
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Itsasne De la Torre Sanchez

Itsasne De la Torre Sanchez

Predoctoral researcher
Neurovascular Diseases
Read more
Laia Fernandez Resano

Laia Fernandez Resano

Main researcher
Neurovascular Diseases
Read more
Liubovi Sopco

Liubovi Sopco

Predoctoral researcher
Neurovascular Diseases
Read more
Marina Pérez González

Marina Pérez González

Predoctoral researcher
Neurovascular Diseases
Read more
Marta Kinga Klimczak

Marta Kinga Klimczak

Predoctoral researcher
Neurovascular Diseases
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Projects

PReDICT: Pediatric Stroke Rare Disorders: Integrative Diagnosis and Treatment using Multi-Omics and Deep Learning

IP: Belen Perez Dueñas
Collaborators: Marta Codina Solà, Maria Mar Hernandez Guillamon, Anna Rosell Novel, David Gómez Andrés
Funding agency: Instituto de Salud Carlos III
Funding: 185165.07
Reference: PMPER24/00021
Duration: 01/01/2025 - 31/12/2026

Administració endovascular de nanomaterials terapèutics per la recuperació de l’ictus.

IP: Anna Rosell Novel
Collaborators: Anna Penalba Morenilla, Administració endovascular de nanomaterials terapèutics per la recuperació de l’ictus., Miguel García Gabilondo
Funding agency: Fundació La Marató de TV3
Funding: 173750
Reference: 202333-30
Duration: 22/04/2024 - 21/04/2027

Aneurismas degenerativos de la aorta ascendente: ¿están relacionados los fenotipos de dilatación con su etiología, patofisiología y pronóstico?

IP: Jose Fernando Rodríguez Palomares
Collaborators: Javier Solsona Caravaca, Guillem Casas Masnou, Ruperto Olivero Soldevila, Alicia Fresno González, Javier Limeres Freire, Raul Aguilar Lopez, Miguel García Gabilondo
Funding agency: Instituto de Salud Carlos III
Funding: 200000
Reference: PI23/01397
Duration: 01/01/2024 - 30/06/2028

Papel de la proteína MFGE8 como potencial biomarcador y diana terapéutica en la angiopatía amiloide cerebral

IP: Maria Mar Hernandez Guillamon
Collaborators: Berta Paez Montserrat, Jessica Camacho Soriano, Anas Chaachou Charradi, Olalla Pancorbo Rosal
Funding agency: Instituto de Salud Carlos III
Funding: 208750
Reference: PI23/00082
Duration: 01/01/2024 - 30/06/2028

Blog

News

The research explores whether a blood test could complement the assessment of recovery after stroke.

The Neurovascular Diseases group at VHIR will use disease models to study its pathophysiological mechanisms.

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research