About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The clinical and basic research activity of the Ophthalmology Research Group is dedicated to finding new treatments for blindness through the development of new therapies for macular and retinal degenerative diseases, as well as for retinal vascular diseases (diabetic retinopathy and retinal vascular occlusions). Our group consists of core researchers and clinical researchers, so there is a clear clinical translation of the ongoing research in the research group.
We have a research program for the development of new therapeutic strategies based on:
In the clinical part, the research group bases its activity on clinical trials to develop new treatments for retinal diseases as well as on the ophthalmic involvement of systemic treatments, an example is the phase II trial to test mesenchymal cells (MSV) intravitreal in non-arteritic ischemic optic neuropathy (NAION), the RECOGNISED study or the PULSAR study with aflibercept.
IP: Rafael Simó Canonge Collaborators: Marina Jimenez Iglesias, Cristina Hernández Pascual, Jaume Rigo Quera, Queralt Martin Saladich, Retinal and cognitive dysfunction in type 2 diabetes: unraveling the common pathways and identification of patients at risk of d, Patricia Bogdanov Baruj, Andreea Ciudin Mihai, Ferran Casals Riera, Maddalen Zufiaurre Seijo, Enrique Franky Vargas Funding agency: EUROPEAN COMMISSION Funding: 950410 Reference: RECOGNISED_H2020SC1BHC2019 Duration: 01/01/2020 - 31/12/2024
IP: Anna Duarri Piqué Collaborators: José García Arumí, Jordi Rosell Aluja, Victor Franco Puntes, Helena Isla Magrané, Joana Ramis Garcia Funding agency: Instituto de Salud Carlos III Funding: 174845 Reference: AC19/00080 Duration: 01/01/2020 - 30/06/2024
IP: Olga Simó Servat Collaborators: Ana Boixadera Espax, Marina Giralt Arnaiz, Cristina Udina Argilaga Funding agency: Instituto de Salud Carlos III Funding: 82280 Reference: PI20/01703 Duration: 01/01/2021 - 30/06/2025
IP: Rafael Simó Canonge Collaborators: Marc Rivas Agudo, Cristina Hernández Pascual, José García Arumí Funding agency: Instituto de Salud Carlos III Funding: 573650 Reference: ICI20/00129 Duration: 01/01/2021 - 31/10/2026
PMID: 37879444 Journal: ANNALS OF ONCOLOGY Year: 2023 Reference: Ann Oncol. 2023 Oct 17:S0923-7534(23)04281-3. doi: 10.1016/j.annonc.2023.10.117. Impact factor: Publication type: Paper in international publication Authors: Augustin, Salvador; Azuma, K; Baneras, Jordi; Barala, P; Bauml, J M; Bearz, A; Boixadera, Anna; Bourla, A B; Califano, R; Campelo, R G et al. DOI: 10.1016/j.annonc.2023.10.117
PMID: 37924946 Journal: Ophthalmology. Retina Year: 2023 Reference: Ophthalmol Retina. 2023 Nov 2:S2468-6530(23)00573-0. doi: 10.1016/j.oret.2023.10.022. Impact factor: Publication type: Paper in international publication Authors: Abraldes, Maximino; Alforja, Socorro; Arruabarrena, Carolina; Bardia, Aditya; Barthelmes, Daniel; Bellet-Ezquerra, Meritxell; Bernal-Morales, Carolina; Bond, John W; Boni, Valentina; Broc-Iturralde, Laura et al. DOI: 10.1016/j.oret.2023.10.022
PMID: 37923065 Journal: Actas dermo-sifiliograficas Year: 2023 Reference: Actas Dermosifiliogr. 2023 Nov 1:S0001-7310(23)00866-9. doi: 10.1016/j.ad.2023.10.032. Impact factor: Publication type: Paper in international publication Authors: Abraldes Lopez-Veiga, Maximino Jose; Abraldes, Maximino; Aldazabal-Echeveste, Maialen; Alforja, Socorro; Alforja, Socorro; Alonso, Elena; Arias-Barquet, Lluis; Arruabarrena, Carolina; Arruabarrena, Carolina; Ascaso Puyuelo, Francisco Javier et al. DOI: 10.1016/j.ad.2023.10.032
PMID: 32301031 Journal: Sleep and Breathing Year: 2021 Reference: Sleep Breath. 2021 Mar;25(1):163-169. doi: 10.1007/s11325-020-02019-y. Epub 2020 Apr 16. Impact factor: 2.816 Publication type: Paper in international publication Authors: Catala-Mora, Jaume, Anton, Alfonso, Perez-Hoyos, Santiago, Carceller, Amadeu, Aparicio, Gloria, Castany-Aregall, Marta, Grau, Nuria et al. DOI: 10.1007/s11325-020-02019-y
PMID: 33738324 Journal: Molecular Therapy-Methods & Clinical Development Year: 2021 Reference: Mol Ther Methods Clin Dev. 2021 Feb 10;20:688-702. doi: 10.1016/j.omtm.2021.02.006. eCollection 2021 Mar 12. Impact factor: 6.698 Publication type: Paper in international publication Authors: Garcia-Arumi, Jose, Veiga, Anna, Zapata, Miguel Angel, Salas, Anna, Duarri, Anna, Fontrodona, Laura, Ramirez, Diana Mora, Badia, Anna, Isla-Magrane, Helena, Ferreira-de-Souza, Barbara et al. DOI: 10.1016/j.omtm.2021.02.006
PMID: 33720541 Journal: ACTA OPHTHALMOLOGICA Year: 2021 Reference: Acta Ophthalmol. 2021 Dec;99(8):861-870. doi: 10.1111/aos.14786. Epub 2021 Mar 15. Impact factor: 3.761 Publication type: Paper in international publication Authors: Galvez, Maria Isabel Lopez, Saenz-de-Viteri, Manuel, Recalde, Sergio, Fernandez-Robredo, Patricia, Lopez Galvez, Maria Isabel, Arias Barquet, Lluis, Figueroa, Marta S, Garcia-Arumi, Jose, Garcia-Layana, Alfredo, Figueroa, Marta S et al. DOI: 10.1111/aos.14786
PMID: 33184677 Journal: INTERNATIONAL OPHTHALMOLOGY Year: 2021 Reference: Int Ophthalmol. 2021 Mar;41(3):787-796. doi: 10.1007/s10792-020-01631-x. Epub 2020 Nov 12. Impact factor: 2.031 Publication type: Paper in international publication Authors: Moll-Udina, Aina, Figueras-Roca, Marc, Oliveres, Joan, Sala-Puigdollers, Anna, Esquinas, Cristina, Alba-Linero, Carmen, Llorenc, Victor, Adan, Alfredo et al. DOI: 10.1007/s10792-020-01631-x
PMID: 32546953 Journal: Clinical ophthalmology (Auckland, N.Z.) Year: 2020 Reference: Clin Ophthalmol. 2020 May 27;14:1451-1457. doi: 10.2147/OPTH.S255086. eCollection 2020. Impact factor: 0 Publication type: Paper in international publication Authors: Alzaben, Zeyad, Gammoh, Yazan, Freixas, Marta, Zaben, Ahmad, Zapata, Miguel A, Koff, Dana N et al. DOI: 10.2147/OPTH.S255086
PMID: 32508622 Journal: Case reports in ophthalmology Year: 2020 Reference: Case Rep Ophthalmol. 2020 May 5;11(2):161-166. doi: 10.1159/000507609. eCollection 2020 May-Aug. Impact factor: 0 Publication type: Letter or abstract Authors: R Andrade, Antonio, Moll-Udina, Aina, Cilveti, Esther, Subira, Olaia, Disfetano, Laura, Garcia-Arumi, Jose, Martin, Ruth et al. DOI: 10.1159/000507609
PMID: 32344735 Journal: Journal of Clinical Medicine Year: 2020 Reference: J Clin Med. 2020 Apr 24;9(4). pii: jcm9041233. doi: 10.3390/jcm9041233. Impact factor: 3.303 Publication type: Paper in international publication Authors: Egan, Catherine, Hernandez, Cristina, Porta, Massimo, Bandello, Francesco, Grauslund, Jakob, Harding, Simon P, Aldington, Stephen J, Gibson, Jonathan, Lang, Gabriele E, Lattanzio, Rosangela et al. DOI: 10.3390/jcm9041233
PMID: 32349099 Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES Year: 2020 Reference: Retina. 2020 Aug;40(8):e38-e39. doi: 10.1097/IAE.0000000000002832. Impact factor: 3.649 Publication type: Letter or abstract Authors: Copete, Sergio, Pastor-Idoate, Salvador, Garcia-Arumi, Josep, Zapata, Miguel A et al. DOI: 10.1097/IAE.0000000000002832
PMID: 31451909 Journal: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY Year: 2019 Reference: Graefes Arch Clin Exp Ophthalmol. 2019 Nov;257(11):2381-2390. doi: 10.1007/s00417-019-04446-4. Epub 2019 Aug 26. Impact factor: 2.25 Publication type: Paper in international publication Authors: Fonollosa, Alejandro, Zarranz-Ventura, Javier, Valverde, Alicia, Becerra, Erika, Bernal-Morales, Carolina, Pastor-Idoate, Salvador, Zapata, Miguel Angel et al. DOI: 10.1007/s00417-019-04446-4
PMID: 31412332 Journal: OPHTHALMOLOGICA Year: 2019 Reference: Ophthalmologica. 2019;242(3):123-162. doi: 10.1159/000502041. Epub 2019 Aug 14. Impact factor: 1.781 Publication type: Paper in international publication Authors: Schmidt-Erfurth, Ursula, Garcia-Arumi, Jose, Gerendas, Bianca S, Midena, Edoardo, Sivaprasad, Sobha, Tadayoni, Ramin, Wolf, Sebastian, Loewenstein, Anat et al. DOI: 10.1159/000502041
PMID: 31363832 Journal: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY Year: 2019 Reference: Graefes Arch Clin Exp Ophthalmol. 2019 Nov;257(11):2547-2558. doi: 10.1007/s00417-019-04420-0. Epub 2019 Jul 30. Impact factor: 2.25 Publication type: Paper in international publication Authors: Bove Alvarez, Maria, Arumi, Claudia Garcia, Distefano, Laura, Guell, Jose Luis, Gris, Oscar, Mateo, Carlos, Corcostegui, Borja, Garcia-Arumi, Jose et al. DOI: 10.1007/s00417-019-04420-0
PMID: 31205783 Journal: Journal of Ophthalmology Year: 2019 Reference: J Ophthalmol. 2019 May 7;2019:6723824. doi: 10.1155/2019/6723824. eCollection 2019. Impact factor: 1.58 Publication type: Paper in international publication Authors: Peralta Iturburu, Federico, Garcia-Arumi, Claudia, Bove Alvarez, Maria, Garcia-Arumi, Jose et al. DOI: 10.1155/2019/6723824
PMID: 28188020 Journal: Archivos de la Sociedad Espanola de Oftalmologia Year: 2017 Reference: Arch Soc Esp Oftalmol. 2017 Jun;92(6):273-279. doi: 10.1016/j.oftal.2016.11.018. Epub 2017 Feb 8. Impact factor: 0 Publication type: Paper in national publication Authors: Velazquez-Villoria, D, Macia-Badia, C, Segura-Garcia, A, Pastor Idoate, S, Arcos-Algaba, G, Velez-Escola, L, Garcia-Arumi, J et al. DOI: 10.1016/j.oftal.2016.11.018
PMID: 27228051 Journal: Telemedicine and e-Health Year: 2017 Reference: Telemed J E Health. 2017 Jan;23(1):30-36. doi: 10.1089/tmj.2016.0020. Epub 2016 May 26. Impact factor: 2.031 Publication type: Paper in international publication Authors: Zapata, Miguel A, Arcos, Gabriel, Fonollosa, Alex, Abraldes, Maximino, Olenik, Andrea, Gutierrez, Estanislao, Garcia-Arumi, Jose et al. DOI: 10.1089/tmj.2016.0020
PMID: 25075124 Journal: BRITISH JOURNAL OF OPHTHALMOLOGY Year: 2015 Reference: Br J Ophthalmol. 2015 Jan;99(1):41-8. doi: 10.1136/bjophthalmol-2014-305263. Epub 2014 Jul 29. Impact factor: 2.976 Publication type: Paper in international publication Authors: Navea, Amparo, Rocha-Sousa, Amandio, Brion, Maria, Carracedo, Angel, Alfaiate, Mario, Boixadera, Anna, Coco, Rosa Maria, de la Fuente, Miguel A, Desco, Carmen, Diaz-Llopis, Manuel et al. DOI: 10.1136/bjophthalmol-2014-305263
PMID: 26394206 Journal: OPHTHALMIC RESEARCH Year: 2015 Reference: Ophthalmic Res. 2015;54(3):143-9. doi: 10.1159/000438759. Epub 2015 Sep 23. Impact factor: 1.422 Publication type: Paper in international publication Authors: Mazzarella, Stefania, Mateo, Carlos, Freixes, Silvia, Bures-Jelstrup, Anniken, Rios, Jose, Navarro, Rafael, Garcia-Arumi, Jose, Corcostegui, Borja, Arrondo, Elena et al. DOI: 10.1159/000438759
PMID: 26065358 Journal: OPHTHALMIC RESEARCH Year: 2015 Reference: Ophthalmic Res. 2015;54(1):34-40. doi: 10.1159/000430955. Epub 2015 Jun 6. Impact factor: 1.422 Publication type: Paper in international publication Authors: Garcia-Arumi, Jose, Distefano, Laura N, Fonollosa, Alex, Quijano, Claudia, Corcostegui, Borja et al. DOI: 10.1159/000430955
PMID: 25478863 Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES Year: 2015 Reference: Retina. 2015 Mar;35(3):398-406. doi: 10.1097/IAE.0000000000000367. Impact factor: 3.243 Publication type: Paper in international publication Authors: Zaben, Ahmad, Zapata, Miguel A, Garcia-Arumi, Jose et al. DOI: 10.1097/IAE.0000000000000367
PMID: 24183659 Journal: TRENDS ENDOCRIN MET Year: 2014 Reference: Trends Endocrinol Metab. 2014 Jan;25(1):23-33. doi: 10.1016/j.tem.2013.09.005. Epub 2013 Nov 1. Impact factor: 8.868 Publication type: Paper in international publication Authors: Simo, Rafael, Hernandez, Cristina, Bandello, F, Burks, D, Cunha-Vaz, J, Egan, C, Garcia-Arumi, J, Gibson, J, Harding, S, Karadeniz, S et al. DOI: 10.1016/j.tem.2013.09.005
PMID: 22366902 Journal: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES Year: 2012 Reference: Retina. 2012 May;32(5):936-41. doi: 10.1097/IAE.0b013e318232c366. Impact factor: 2.812 Publication type: Paper in international publication Authors: , , , , , , , , et al. DOI: 10.1097/IAE.0b013e318232c366
PMID: 19822846 Journal: ARCHIVES OF OPHTHALMOLOGY Year: 2009 Reference: Arch Ophthalmol. 2009 Oct;127(10):1297-304. Impact factor: 3.242 Publication type: Paper in international publication Authors: Martinez-Castillo, Vicente, Boixadera, Anna, Garcia-Arumi, Jose et al. DOI: 10.1001/archophthalmol.2009.254
PMID: 19823802 Journal: DIABETOLOGIA Year: 2009 Reference: Diabetologia. 2009 Dec;52(12):2633-41. Impact factor: 6.418 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1007/s00125-009-1548-8
On January 24, a session was held to explain what these three-dimensional models are and what advantages they have, as well as to review some of their applications in research.
Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.
Dr. José García Arumi and Dr. Anna Duarri from the Ophthalmology research group at Vall Hebron Recerca lead the project.
