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Peripheral Nervous System

Our laboratory, in the Neuromuscular Disorders Unit of the Neurology Service, has a twenty-year history of clinical care and research into amyotrophic lateral sclerosis (ALS) and other motor neurone diseases (hereditary, spastic paraplegia, post-polio syndrome, Hirayama disease, spinal muscular atrophy), myasthenia gravis, genetically determined myopathies, and peripheral neuropathies. Our main lines of research focus on the molecular mechanisms of amyotrophic lateral sclerosis and how genetic mutations in family ELA predispose or modify genetic factors. We also look for effective biomarkers in blood and in cerebrospinal fluid that allow the evaluation of new medication.

Team

Daniel Sánchez-Tejerin San José

Daniel Sánchez-Tejerin San José

Predoctoral researcher
Peripheral Nervous System
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David Ovelleiro Fraile

David Ovelleiro Fraile

Postdoctoral researcher
Peripheral Nervous System
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Javier Joaquín Sotoca  Fernández

Javier Joaquín Sotoca Fernández

Predoctoral researcher
Peripheral Nervous System
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José Manuel Vidal Taboada

José Manuel Vidal Taboada

Main researcher
Peripheral Nervous System
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Raul Juntas Morales

Raul Juntas Morales

Head of group
Peripheral Nervous System
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Daniel Sánchez-Tejerin San José

Daniel Sánchez-Tejerin San José

Predoctoral researcher
Peripheral Nervous System
Read more
David Ovelleiro Fraile

David Ovelleiro Fraile

Postdoctoral researcher
Peripheral Nervous System
Read more
Javier Joaquín Sotoca  Fernández

Javier Joaquín Sotoca Fernández

Predoctoral researcher
Peripheral Nervous System
Read more
José Manuel Vidal Taboada

José Manuel Vidal Taboada

Main researcher
Peripheral Nervous System
Read more
Raul Juntas Morales

Raul Juntas Morales

Head of group
Peripheral Nervous System
Read more

Projects

Genotipado de alta resolución de los genes HLA y análisis de su expresión en el SNC en Esclerosis Lateral Amiotrófica como factor de riesgo: Investigando la hipótesis neuroinflamatoria

IP: José Manuel Vidal Taboada
Collaborators: Maria Jose Herrero Mata, Maria Salvadó Figueras, Josep Gamez Carbonell, Consuelo Garcia Carmona, Arnau Llauradó Gayete
Funding agency: Instituto de Salud Carlos III
Funding: 117370
Reference: PI19/00593
Duration: 01/01/2020 - 30/06/2024

Publications

Implications of starting antiepileptic treatment prior to electroencephalography in first epileptic seizures.

PMID: 37858895
Journal: Neurologia
Year: 2023
Reference: Neurologia (Engl Ed). 2023 Oct 17:S2173-5808(23)00054-8. doi: 10.1016/j.nrleng.2021.02.010.
Impact factor:
Publication type: Paper in international publication
Authors: Abraira, L; Ballve, A; Campos, D; Costa E Silva, Matheus; Dienstmann, Rodrigo; Fonseca, E; Gil Ferreira, Carlos; Llaurado, A; Lopes David, Bruna Bianca; Nazareth Aguiar Junior, Pedro et al.
DOI: 10.1016/j.nrleng.2021.02.010

Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.

PMID: 37034728
Journal:
Year: 2023
Reference: medRxiv. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. Preprint.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Abraira, L; Ballve, A; Batzler, Anthony; Bianchi, Sevim B; Biernacka, Joanna M; Campos, D; Coombes, Brandon J; Cox, Nancy J; Davis, Lea K; Ehinmowo, Michael et al.
DOI: 10.1101/2023.03.27.23287713

Titin copy number variations associated with dominant inherited phenotypes.

PMID: 37935568
Journal: JOURNAL OF MEDICAL GENETICS
Year: 2023
Reference: J Med Genet. 2023 Nov 7:jmg-2023-109473. doi: 10.1136/jmg-2023-109473.
Impact factor:
Publication type: Paper in international publication
Authors: Alonso Pacheco, M L; Baniandres Rodriguez, O; Beggs, Alan; Ben Yaou, Rabah; Bertini, Enrico Silvio; Bloch, Adrien; Boespflug-Tanguy, Odile; Bonne, Gisele; Chapon, Francoise; Cossee, Mireille et al.
DOI: 10.1136/jmg-2023-109473

Anticoagulation and Bleeding during Veno-Venous Extracorporeal Membrane Oxygenation: Insights from the PROTECMO Study.

PMID: 37943110
Journal: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
Year: 2023
Reference: Am J Respir Crit Care Med. 2023 Nov 9. doi: 10.1164/rccm.202305-0896OC.
Impact factor:
Publication type: Paper in international publication
Authors: Agerstrand, Cara; Ait Hssain, Ali; Arcadipane, Antonio; Balik, Martin; Beggs, Alan; Ben Yaou, Rabah; Bertini, Enrico Silvio; Bloch, Adrien; Boespflug-Tanguy, Odile; Bonne, Gisele et al.
DOI: 10.1164/rccm.202305-0896OC