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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

A human gut microbial gene catalogue established by metagenomic sequencing.

PMID: 20203603
Journal: NATURE
Year: 2010
Reference: Nature. 2010 Mar 4;464(7285):59-65.
Impact factor: 34.48
Publication type: Paper in international publication
Authors: Dore, Joel, Batto, Jean-Michel, Hansen, Torben, Le Paslier, Denis, Linneberg, Allan, Nielsen, H Bjorn, Pelletier, Eric, Renault, Pierre, Sicheritz-Ponten, Thomas, Turner, Keith et al.
DOI: 10.1038/nature08821

A Long-Term Study of Changes in the Volume of Brain Ventricles and White Matter Lesions After Successful Liver Transplantation.

PMID: 20118844
Journal: TRANSPLANTATION
Year: 2010
Reference: Transplantation. 2010 Mar 15;89(5):589-94.
Impact factor: 3.498
Publication type: Paper in international publication
Authors: , , , , , , , , et al.
DOI: 10.1097/TP.0b013e3181ca7bb3

A Major Role of p95/611-CTF, a Carboxy-Terminal Fragment of HER2, in the Down-modulation of the Estrogen Receptor in HER2-Positive Breast Cancers.

PMID: 20978202
Journal: CANCER RESEARCH
Year: 2010
Reference: Cancer Res. 2010 Nov 1;70(21):8537-46. Epub 2010 Oct 26.
Impact factor: 7.543
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1158/0008-5472.CAN-10-1701

A missense HTRA1 mutation expands CARASIL syndrome to the Caucasian population.

PMID: 21115960
Journal: NEUROLOGY
Year: 2010
Reference: Neurology. 2010 Nov 30;75(22):2033-5.
Impact factor: 8.172
Publication type: Editorail in international publication
Authors: Mendioroz, M, Fernandez-Cadenas, I, Del Rio-Espinola, A, Rovira, A, Sole, E, Fernandez-Figueras, M T, Garcia-Patos, V, Sastre-Garriga, J, Domingues-Montanari, S, Alvarez-Sabin, J et al.
DOI: 10.1212/WNL.0b013e3181ff96ac

A molecular risk score based on four functional pathways for advanced classical Hodgkin lymphoma.

PMID: 20479282
Journal: BLOOD
Year: 2010
Reference: Blood. 2010 Aug 26;116(8):e12-7. Epub 2010 May 17.
Impact factor: 10.555
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1182/blood-2010-02-270009

A multicentre phase II gene expression profiling study of putative relationships between tumour biomarkers and clinical response with erlotinib in non-small-cell lung cancer.

PMID: 20110292
Journal: ANNALS OF ONCOLOGY
Year: 2010
Reference: Ann Oncol. 2010 Feb;21(2):217-22.
Impact factor: 5.647
Publication type: Paper in international publication
Authors: Baselga, J, Tan, E-H, Ramlau, R, Pluzanska, A, Kuo, H-P, Reck, M, Milanowski, J, Felip, E, Yang, P-C, Damyanov, D et al.
DOI: 10.1093/annonc/mdp520

A multi-centre study of efficacy and safety of Intratect((R)), a novel intravenous immunoglobulin preparation.

PMID: 20550545
Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Year: 2010
Reference: Clin Exp Immunol. 2010 Sep;161(3):512-7. doi: 10.1111/j.1365-2249.2010.04187.x.
Impact factor: 3.009
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1111/j.1365-2249.2010.04187.x

A mutation in the first intracellular loop of CACNA1A prevents P/Q channel modulation by SNARE proteins and lowers exocytosis.

PMID: 20080591
Journal: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Year: 2010
Reference: Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1672-7. Epub 2010 Jan 8.
Impact factor: 9.432
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1073/pnas.0908359107

A new application of Streptavidin ImmunoCAP for measuring IgG antibodies against non-available commercial antigens.

PMID: 20619254
Journal: CLINICA CHIMICA ACTA
Year: 2010
Reference: Clin Chim Acta. 2010 Nov 11;411(21-22):1675-8. Epub 2010 Jul 6.
Impact factor: 2.535
Publication type: Paper in international publication
Authors: Rodrigo, Maria J, Postigo, Idoia, Wangensteen, Owen, Guisantes, Jorge A, Martinez, Jorge et al.
DOI: 10.1016/j.cca.2010.06.031

A new culture technique that allows in vitro meiotic prophase development of fetal human oocytes.

PMID: 19828555
Journal: HUMAN REPRODUCTION
Year: 2010
Reference: Hum Reprod. 2010 Jan;25(1):74-84. Epub 2009 Oct 14.
Impact factor: 3.859
Publication type: Paper in international publication
Authors: Brieno-Enriquez, M A, Robles, P, Garcia-Cruz, R, Roig, I, Cabero, L, Martinez, F, Garcia Caldes, M et al.
DOI: 10.1093/humrep/dep351

A new generation of proto-oncogenes: Cold-inducible RNA binding proteins.

PMID: 19900510
Journal: BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
Year: 2010
Reference: Biochim Biophys Acta. 2010 Jan;1805(1):43-52. Epub 2009 Nov 10.
Impact factor: 11.685
Publication type: Review in international publication
Authors: et al.
DOI: 10.1016/j.bbcan.2009.11.001

A novel de novo BRCA2 mutation of paternal origin identified in a Spanish woman with early onset bilateral breast cancer.

PMID: 19649703
Journal: BREAST CANCER RESEARCH AND TREATMENT
Year: 2010
Reference: Breast Cancer Res Treat. 2010 May;121(1):221-5. Epub 2009 Aug 1.
Impact factor: 4.696
Publication type: Paper in international publication
Authors: Diez, Orland, Gutierrez-Enriquez, Sara, Mediano, Carmen, Masas, Miriam, Saura, Cristina, Gadea, Neus, Balmana, Judith et al.
DOI: 10.1007/s10549-009-0494-y

A phase II trial of first-line sorafenib in patients with metastatic renal cell carcinoma unwilling to receive or with early intolerance to immunotherapy: SOGUG Study 06-01.

PMID: 20615828
Journal: Clinical & Translational Oncology
Year: 2010
Reference: Clin Transl Oncol. 2010 Jul;12(7):503-8.
Impact factor: 1.146
Publication type: Paper in international publication
Authors: Bellmunt, Joaquim, Maroto-Rey, Pablo, Trigo, Jose M, Carles, Joan, Guillem, Vicente, Lopez-Martin, Jose A, Anton-Torres, Antonio, Urruticoechea, Leyrer et al.
DOI:

A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.

PMID: 20459775
Journal: BMC CANCER
Year: 2010
Reference: BMC Cancer. 2010 May 11;10(1):190.
Impact factor: 2.736
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/1471-2407-10-190

A randomised comparison between everolimus-eluting stent and sirolimus-eluting stent in chronic coronary total occlusions. Rationale and design of the CIBELES (non-acute Coronary occlusion treated by EveroLimus-Eluting Stent) trial.

PMID: 20542806
Journal: EuroIntervention
Year: 2010
Reference: EuroIntervention. 2010 May;6(1):112-6. doi: 10.4244/.
Impact factor:
Publication type: Letter or abstract
Authors: Moreno, Raul, Garcia, Eulogio, Teles, Rui C, Almeida, Manuel S, Carvalho, Henrique Cyrne, Sabate, Manel, Martin-Reyes, Roberto, Rumoroso, Jose Ramon, Galeote, Guillermo, Goicolea, Francisco Javier et al.
DOI: 10.4244/

A randomized, double-blind, multicenter study of caspofungin versus liposomal amphotericin B for empiric antifungal therapy in pediatric patients with persistent fever and neutropenia.

PMID: 20431381
Journal: PEDIATRIC INFECTIOUS DISEASE JOURNAL
Year: 2010
Reference: Pediatr Infect Dis J. 2010 May;29(5):415-20.
Impact factor: 2.854
Publication type: Paper in international publication
Authors: Castel Sanchez, P, Garcia Miguel, P, Madero-Lopez, L, Sanchez de Toledo, J, Flynn, P, Green, M, Jafri, H, Nania, J, Pulsipher, M, Reilly, A et al.
DOI: 10.1097/INF.0b013e3181da2171

A Strong Genetic Association between the Tumor Necrosis Factor Locus and Proliferative Vitreoretinopathy: The Retina 4 Project.

PMID: 20663564
Journal: OPHTHALMOLOGY
Year: 2010
Reference: Ophthalmology. 2010 Dec;117(12):2417-2423.e1-2. Epub 2010 Jul 21.
Impact factor: 5.491
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1016/j.ophtha.2010.03.059

A study of right-left shunt in transient global amnesia.

PMID: 20487707
Journal: NEUROLOGIA
Year: 2010
Reference: Neurologia. 2010 Mar;25(2):83-89.
Impact factor: 0.596
Publication type: Paper in national publication
Authors: , , , , , , , et al.
DOI:

A transcriptional signature associated with the onset of benign prostate hyperplasia in a canine model.

PMID: 20687213
Journal: PROSTATE
Year: 2010
Reference: Prostate. 2010 Sep 15;70(13):1402-12.
Impact factor: 3.081
Publication type: Paper in international publication
Authors: Gallardo-Arrieta, F, Doll, A, Rigau, M, Mogas, T, Juanpere, N, Garcia, F, Morote, J, Nunez, F, Abal, M, Lloreta, J et al.
DOI: 10.1002/pros.21175

Abacavir-based therapy does not affect biological mechanisms associated with cardiovascular dysfunction.

PMID: 20009917
Journal: AIDS
Year: 2010
Reference: AIDS. 2010 Jan 28;24(3):F1-9.
Impact factor: 4.909
Publication type: Paper in international publication
Authors: Martinez, Esteban, Larrousse, Maria, Podzamczer, Daniel, Perez, Ignacio, Gutierrez, Felix, Barragan, Patricia, Deulofeu, Ramon, Casamitjana, Roser, Mallolas, Josep, Pich, Judit et al.
DOI: 10.1097/QAD.0b013e32833562c5

Ability of treatment week 12 viral response to predict long-term outcome in genotype 1 hepatitis C virus/HIV coinfected patients.

PMID: 20299963
Journal: AIDS
Year: 2010
Reference: AIDS. 2010 Apr 24;24(7):975-82.
Impact factor: 4.909
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1097/QAD.0b013e3283350f7c

Activity of a silver-coated endotracheal tube in preclinical models of ventilator-associated pneumonia and a study after extubation.

PMID: 20081533
Journal: CRITICAL CARE MEDICINE
Year: 2010
Reference: Crit Care Med. 2010 Apr;38(4):1135-40.
Impact factor: 6.373
Publication type: Paper in international publication
Authors: Rello, Jordi, Afessa, Bekele, Anzueto, Antonio, Arroliga, Alejandro C, Olson, Merle E, Restrepo, Marcos I, Talsma, Silke S, Bracken, Ronald L, Kollef, Marin H et al.
DOI: 10.1097/CCM.0b013e3181cd12b8

[Acute cholangitis.]

PMID: 21130926
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2010
Reference: Enferm Infecc Microbiol Clin. 2010 Sep;28S2:18-24.
Impact factor: 1.393
Publication type: Paper in national publication
Authors: , et al.
DOI: 10.1016/S0213-005X(10)70026-4

Acute esophageal variceal bleeding: Current strategies and new perspectives.

PMID: 21161008
Journal: World journal of hepatology
Year: 2010
Reference: World J Hepatol. 2010 Jul 27;2(7):261-74.
Impact factor:
Publication type: Letter or abstract
Authors: Gonzalez, Antonio, Genesca, Joan, Augustin, Salvador et al.
DOI: 10.4254/wjh.v2.i7.261