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The science produced by our scientists is very important. In 2022, 1,629 papers were published in scientific journals with a global impact factor of over 15,000 points.

TGF-beta increases glioma-initiating cell self-renewal through the induction of LIF in human glioblastoma.

PMID: 19345330
Journal: CANCER CELL
Year: 2009
Reference: Cancer Cell. 2009 Apr 7;15(4):315-27.
Impact factor: 24.962
Publication type: Paper in international publication
Authors: Penuelas, Silvia, Anido, Judit, Prieto-Sanchez, Rosa M, Folch, Gerard, Cuartas, Isabel, Garcia-Dorado, David, Poca, M Antonia, Sahuquillo, Juan, Baselga, Jose, Seoane, Joan et al.
DOI: 10.1016/j.ccr.2009.02.011

Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza.

PMID: 20003352
Journal: CRITICAL CARE
Year: 2009
Reference: Crit Care. 2009;13(6):R201. doi: 10.1186/cc8208. Epub 2009 Dec 11.
Impact factor: 4.553
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1186/cc8208

The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.

PMID: 19561607
Journal: NATURE GENETICS
Year: 2009
Reference: Nat Genet. 2009 Aug;41(8):882-4.
Impact factor: 30.259
Publication type: Paper in international publication
Authors: Beckwith, Christine A, Chan, Jennifer A, Hills, Adam, Davis, Matt, Yao, Keluo, Kehoe, Sarah M, Lenz, Heinz-Josef, Haiman, Christopher A, Yan, Chunli, Henderson, Brian E et al.
DOI: 10.1038/ng.403

The calcium-sensing receptor and parathyroid hormone-related protein are expressed in differentiated, favorable neuroblastic tumors.

PMID: 19350667
Journal: CANCER
Year: 2009
Reference: Cancer. 2009 Jun 15;115(12):2792-803.
Impact factor: 5.238
Publication type: Paper in international publication
Authors: Diaz, Ruben, Toran, Nuria, Rodriguez, Eva, Lavarino, Cinzia, Garcia, Idoia, Acosta, Sandra, Sunol, Mariona, Mora, Jaume, Beleta, Helena, de Torres, Carmen et al.
DOI: 10.1002/cncr.24304

The challenge of developing new therapies for irritable bowel syndrome.

PMID: 21180543
Journal: Therapeutic advances in gastroenterology
Year: 2009
Reference: Therap Adv Gastroenterol. 2009 Jul;2(4):201-3. doi: 10.1177/1756283X09335638.
Impact factor: 0
Publication type: Editorail in international publication
Authors: Whorwell, Peter J, Azpiroz, Fernando et al.
DOI: 10.1177/1756283X09335638

The changing face of HIV/AIDS in treated patients.

PMID: 19601771
Journal: CURRENT HIV RESEARCH
Year: 2009
Reference: Curr HIV Res. 2009 Jul;7(4):365-77.
Impact factor: 2.495
Publication type: Review in national publication
Authors: Tural, Cristina, Negredo, Eugenia, Pineda, Juan A, Munoz, Jose, Ortega, Enrique, Videla, Sebastia, Sirera, Guillem, Martinez, Esteban, Miralles, Celia, Iribarren, Josean et al.
DOI:

The dynamic DNA methylomes of double-stranded DNA viruses associated with human cancer.

PMID: 19208682
Journal: GENOME RESEARCH
Year: 2009
Reference: Genome Res. 2009 Mar;19(3):438-51.
Impact factor: 10.176
Publication type: Paper in international publication
Authors: Fernandez, Agustin F, Rosales, Cecilia, Lopez-Nieva, Pilar, Grana, Osvaldo, Ballestar, Esteban, Ropero, Santiago, Espada, Jesus, Melo, Sonia A, Lujambio, Amaia, Fraga, Mario F et al.
DOI: 10.1101/gr.083550.108

The emergence of lymphogranuloma venereum in Europe.

PMID: 19632496
Journal: LANCET
Year: 2009
Reference: Lancet. 2009 Jul 25;374(9686):356.
Impact factor: 28.409
Publication type: Editorail in international publication
Authors: Vall-Mayans, Marti, Caballero, Estrella, Sanz, Benicio et al.
DOI: 10.1016/S0140-6736(09)60993-4

The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma.

PMID: 19585519
Journal: JOURNAL OF PATHOLOGY
Year: 2009
Reference: J Pathol. 2009 Oct;219(2):205-13.
Impact factor: 5.121
Publication type: Paper in international publication
Authors: Martinez-Romero, Carles, Rooman, Ilse, Skoudy, Anouchka, Guerra, Carmen, Molero, Xavier, Gonzalez, Ana, Iglesias, Mar, Lobato, Tania, Bosch, Almudena, Barbacid, Mariano et al.
DOI: 10.1002/path.2585

The European Exenatide study of long-term exenatide vs. glimepiride for type 2 diabetes: rationale and patient characteristics.

PMID: 19758357
Journal: DIABETES OBESITY & METABOLISM
Year: 2009
Reference: Diabetes Obes Metab. 2009 Dec;11(12):1131-7.
Impact factor: 4.259
Publication type: Paper in international publication
Authors: , , , , , , , et al.
DOI: 10.1111/j.1463-1326.2009.01091.x

The European internet-based patient and research database for primary immunodeficiencies: results 2006-2008.

PMID: 19630863
Journal: CLINICAL AND EXPERIMENTAL IMMUNOLOGY
Year: 2009
Reference: Clin Exp Immunol. 2009 Sep;157 Suppl 1:3-11.
Impact factor: 2.853
Publication type: Paper in international publication
Authors: Benslama, L, Plebani, A, Notarangelo, L, Pignata, C, Bangs, C, Lucas, M, Tierney, P, Core, C, Dempster, J, Knerr, V et al.
DOI: 10.1111/j.1365-2249.2009.03954.x

The FAS -670A>G polymorphism influences susceptibility to systemic sclerosis phenotypes.

PMID: 19950259
Journal: ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
Year: 2009
Reference: Arthritis Rheum. 2009 Dec;60(12):3815-20.
Impact factor: 6.787
Publication type: Paper in international publication
Authors: Broen, J, Gourh, P, Rueda, B, Coenen, M, Mayes, M, Martin, J, Arnett, F C, Radstake, T R D J, Broen, J, Vonk, M C et al.
DOI: 10.1002/art.24964

The hemiplegic migraine-associated Y1245C mutation in CACNA1A results in a gain of channel function due to its effect on the voltage sensor and G-protein-mediated inhibition.

PMID: 19189122
Journal: PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
Year: 2009
Reference: Pflugers Arch. 2009 Jul;458(3):489-502.
Impact factor: 3.526
Publication type: Paper in international publication
Authors: Serra, Selma A, Fernandez-Castillo, Noelia, Macaya, Alfons, Cormand, Bru, Valverde, Miguel A, Fernandez-Fernandez, Jose M et al.
DOI: 10.1007/s00424-009-0637-3

The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype.

PMID: 18713787
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2009
Reference: Ann Rheum Dis. 2009 Feb;68(2):253-6.
Impact factor: 7.188
Publication type: Paper in international publication
Authors: Pros, A, Camps, M T, Gonzalez-Gay, M A, Martin, J, Radstake, T R D J, Garcia-Portales, R, Aguirre-Zamorano, M A, Coenen, M J H, Rueda, B, Broen, J et al.
DOI: 10.1136/ard.2008.096719

The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 10th World Congress on Gastrointestinal Cancer, Barcelona, 2008.

PMID: 19497945
Journal: ANNALS OF ONCOLOGY
Year: 2009
Reference: Ann Oncol. 2009 Jun;20 Suppl 7:vii1-vii6.
Impact factor: 4.935
Publication type: Paper in international publication
Authors: Gruenberger, T, Haller, D, Haustermans, K, Hoff, P, Kerr, D, Labianca, R, Moore, M, Nordlinger, B, Ohtsu, A, Rougier, P et al.
DOI: 10.1093/annonc/mdp281

[The mitogen-activated protein kinase (MAPK) signaling pathway in papillary thyroid cancer. From the molecular bases to clinical practice].

PMID: 19627734
Journal: Endocrinol Nutr
Year: 2009
Reference: Endocrinol Nutr. 2009 Apr;56(4):176-86. doi: 10.1016/S1575-0922(09)70982-9. Epub 2009 Jun 11.
Impact factor: 0
Publication type: Review in national publication
Authors: Zafon, Carles, Obiols, Gabriel et al.
DOI: 10.1016/S1575-0922(09)70982-9

[The need to select drugs: the responsibility of choosing]

PMID: 19828213
Journal: Atencion Primaria
Year: 2009
Reference: Aten Primaria. 2009 Dec;41(12):657-8.
Impact factor:
Publication type: Letter or abstract
Authors: Daza, Pablo, de la Figuera, Enrique, Eirea, Carlos, Garcia, Guillermo, Gonzalez, Maria Jesus, Ibanez, Felix, Lorenzo, Antonio, Martinez, Maria Teresa, Menarguez, Juan Francisco, Munoz, Francisco et al.
DOI: 10.1016/j.aprim.2009.09.003

The p.E22G mutation in the Cu/Zn superoxide-dismutase gene predicts a long survival time: clinical and genetic characterization of a seven-generation ALS1 Spanish pedigree.

PMID: 19524271
Journal: JOURNAL OF THE NEUROLOGICAL SCIENCES
Year: 2009
Reference: J Neurol Sci. 2009 Oct 15;285(1-2):46-53.
Impact factor: 2.359
Publication type: Paper in international publication
Authors: Syriani, Enrique, Morales, Miguel, Gamez, Josep et al.
DOI: 10.1016/j.jns.2009.05.011

The receptor tyrosine kinase EPHB4 has tumor suppressor activities in intestinal tumorigenesis.

PMID: 19738063
Journal: CANCER RESEARCH
Year: 2009
Reference: Cancer Res. 2009 Sep 15;69(18):7430-8.
Impact factor: 7.514
Publication type: Paper in international publication
Authors: Dopeso, Higinio, Mateo-Lozano, Silvia, Mazzolini, Rocco, Rodrigues, Paulo, Lagares-Tena, Laura, Ceron, Julian, Romero, Jordi, Esteves, Marielle, Landolfi, Stefania, Hernandez-Losa, Javier et al.
DOI: 10.1158/0008-5472.CAN-09-0706

The relationship between antiretroviral prescription patterns and treatment guidelines in treatment-naive HIV-1-infected patients.

PMID: 19785666
Journal: HIV MEDICINE
Year: 2009
Reference: HIV Med. 2009 Oct;10(9):573-9.
Impact factor: 3.103
Publication type: Paper in international publication
Authors: Suarez-Lozano, I, Viciana, P, Lacalle, J-R, Teira, R, Lozano, F, Lopez-Aldeguer, J, Pedrol, E, Domingo, P, Cosin, J, Roca, B et al.
DOI: 10.1111/j.1468-1293.2009.00731.x

The relationship between total and free serum testosterone and the risk of prostate cancer and tumour aggressiveness.

PMID: 19220251
Journal: BJU INTERNATIONAL
Year: 2009
Reference: BJU Int. 2009 Aug;104(4):486-9.
Impact factor: 2.704
Publication type: Paper in international publication
Authors: Morote, Juan, Ramirez, Cristobal, Gomez, Esther, Planas, Jacques, Raventos, Carles X, de Torres, Ines M, Catalan, Roberto et al.
DOI: 10.1111/j.1464-410X.2009.08378.x

The role of nurses working in emergency and critical care environments in the prevention of intravascular catheter-related bloodstream infections.

PMID: 19135017
Journal: International emergency nursing
Year: 2009
Reference: Int Emerg Nurs. 2009 Jan;17(1):60-8. Epub 2008 Sep 12.
Impact factor:
Publication type: Letter or abstract
Authors: Vandijck, Dominique M, Labeau, Sonia O, Secanell, Mariona, Rello, Jordi, Blot, Stijn I et al.
DOI: 10.1016/j.ienj.2008.07.005

The search for responsive clinical endpoints in primary progressive multiple sclerosis.

PMID: 19383646
Journal: MULTIPLE SCLEROSIS
Year: 2009
Reference: Mult Scler. 2009 Jun;15(6):715-20.
Impact factor: 3.312
Publication type: Paper in international publication
Authors: Bosma, L V A E, Kragt, J J, Brieva, L, Khaleeli, Z, Montalban, X, Polman, C H, Thompson, A J, Tintore, M, Uitdehaag, B M J et al.
DOI: 10.1177/1352458509102626

The second wind phenomenon in very young McArdle's patients.

PMID: 19477644
Journal: NEUROMUSCULAR DISORDERS
Year: 2009
Reference: Neuromuscul Disord. 2009 Jun;19(6):403-5.
Impact factor: 2.932
Publication type: Paper in international publication
Authors: Fernandez Del Valle, Maria, Nogales-Gadea, Gisela, Andreu, Antoni L, Arenas, Joaquin, Lucia, Alejandro, Ruiz, Jonatan R, Perez, Margarita et al.
DOI: 10.1016/j.nmd.2009.04.010