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Research on Aging, Frailty and Transitions in Barcelona

The Research group on Aging, Frailty and Care Transitions in Barcelona (REFiTBcn) stems from the expertise of healthcare professionals of Parc Sanitari Pere Virgili. The group focuses on clinical epidemiology of aging and implementation science of innovative and integrated complex interventions, with the final aim of improving quality of life of older adults, from prevention and promotion of healthy aging to management of frailty.

The main research line include: cardiovascular risk, cognitive impairment and mobility disability; shared decisions and individualized management to improve rehabilitation of stroke and cancer survivors; management of delirium; integrated care in the community to prevent disability or to improve homecare. 

The group maintains top-level international collaborations with Swedish, Canadian, Italian and US centres.

Team

Lorenzo Escutia Mari

Lorenzo Escutia Mari

Research technician
Research on Aging, Frailty and Transitions in Barcelona
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Marcelo Alvarado Cárdenas

Marcelo Alvarado Cárdenas

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Molins Sauri, Marta

Molins Sauri, Marta

Postdoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Sara Navarrete Romero

Sara Navarrete Romero

Research technician
Research on Aging, Frailty and Transitions in Barcelona
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Soler Blanco, Nuria

Soler Blanco, Nuria

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Aida Ribera Sole

Aida Ribera Sole

Main researcher
Research on Aging, Frailty and Transitions in Barcelona
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Lorenzo Escutia Mari

Lorenzo Escutia Mari

Research technician
Research on Aging, Frailty and Transitions in Barcelona
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Marcelo Alvarado Cárdenas

Marcelo Alvarado Cárdenas

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Molins Sauri, Marta

Molins Sauri, Marta

Postdoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Sara Navarrete Romero

Sara Navarrete Romero

Research technician
Research on Aging, Frailty and Transitions in Barcelona
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Soler Blanco, Nuria

Soler Blanco, Nuria

Predoctoral researcher
Research on Aging, Frailty and Transitions in Barcelona
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Aida Ribera Sole

Aida Ribera Sole

Main researcher
Research on Aging, Frailty and Transitions in Barcelona
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Projects

Recerca en Envelliment, Fragilitat i Transicions a Barcelona

IP: Marco Inzitari
Collaborators: Aida Ribera Sole, Luis Ignacio Soto Bargaria, Daniel Sevilla Sánchez, Laura Mónica Perez Bazan, Neus Gual Tarrada, Ana Maria De Andres Lázaro, Cristina Udina Argilaga, Lorena Villa García
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00768
Duration: 01/01/2022 - 30/06/2025

AGIL Barcelona: atención integrada para personas mayores frágiles que viven en la comunidad

IP: Laura Mónica Perez Bazan
Collaborators: Aida Ribera Sole, Luis Ignacio Soto Bargaria, Marco Inzitari
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 50801.25
Reference: SLT021/21/000016
Duration: 01/04/2022 - 31/12/2024

RECEP-HAD - Evaluación de resultados y experiencias centrados en la persona y el impacto económico del hospital a domicilio geriátrico integral: necesidad de un conjunto de herramientas multipropósito

IP: Aida Ribera Sole
Collaborators: Karla Salas Gama, Laura Coll Planas
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/00845
Duration: 01/01/2023 - 31/12/2025

Projecte "A casa"

IP: Marco Inzitari
Collaborators: Lorena Villa García, Laia Perez Lasarte
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 33960
Reference: AGAUR/DI/2020_2/VILLA
Duration: 08/02/2021 - 07/02/2025

Publications

Impact of pembrolizumab versus chemotherapy on health-related quality of life in patients with metastatic triple-negative breast cancer: results from the phase 3 randomised KEYNOTE-119 study.

PMID: 37976633
Journal: EUROPEAN JOURNAL OF CANCER
Year: 2023
Reference: Eur J Cancer. 2023 Oct 21;195:113393. doi: 10.1016/j.ejca.2023.113393.
Impact factor:
Publication type: Paper in international publication
Authors: Abilla, Araceli; Andre, Fabrice; Arnal, Cristina; Ars, Joan; Baro, Sonia; Cesari, Matteo; Cortes, Javier; Dent, Rebecca; Diaz, Francisco; Enfedaque, M Belen et al.
DOI: 10.1016/j.ejca.2023.113393

Biofeedback and Digitalized Motivational Interviewing to Increase Daily Physical Activity: Series of Factorial N-of-1 Randomized Controlled Trials Piloting the Precious App.

PMID: 37995122
Journal: JMIR formative research
Year: 2023
Reference: JMIR Form Res. 2023 Nov 23;7:e34232. doi: 10.2196/34232.
Impact factor:
Publication type: Paper in international publication
Authors: Castellano-Tejedor, Carmina; Gartner, Silvia; Ginchev, Todor; Haukkala, Ari; Iglesias Serrano, Ignacio; Izquierdo, Ana Diez; Khattak, Fida; Knittle, Keegan; Lusilla-Palacios, Pilar; Messa, Ines Mir et al.
DOI: 10.2196/34232

Key Genes of the Immune System and Predisposition to Acquired Hemophilia A: Evidence from a Spanish Cohort of 49 Patients Using Next-Generation Sequencing.

PMID: 38003562
Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Year: 2023
Reference: Int J Mol Sci. 2023 Nov 15;24(22):16372. doi: 10.3390/ijms242216372.
Impact factor:
Publication type: Paper in international publication
Authors: Aguinaco, Reyes; Astigarraga, Itziar; Bastida, Jose Maria; Bernardo, Angel; Carrasco, Marina; Castellano-Tejedor, Carmina; Closa, Laia; Corrales, Irene; Ferrero, Ainara; Garcia-Martinez, Iris et al.
DOI: 10.3390/ijms242216372

Predicting 60-Day Mortality in a Home-Care Service: Development of a New Inter-RAI 49-Frailty Index in Patients With Chronic Disease and Without a Cancer Diagnosis.

PMID: 38081326
Journal: Journal of the American Medical Directors Association
Year: 2023
Reference: J Am Med Dir Assoc. 2023 Dec 8:S1525-8610(23)00943-X. doi: 10.1016/j.jamda.2023.10.028.
Impact factor:
Publication type: Paper in international publication
Authors: Bellelli, Giuseppe; Crippa, Matteo; Lombardi, Fabio; Mazzola, Paolo; Morandi, Alessandro; Re, Massimo; Riva, Luca; Scaccabarozzi, Gianlorenzo; Zambon, Antonella et al.
DOI: 10.1016/j.jamda.2023.10.028

Correlates to psychological distress in frail older community-dwellers undergoing lockdown during the COVID-19 pandemic.

PMID: 35739478
Journal: BMC Geriatrics
Year: 2022
Reference: BMC Geriatr. 2022 Jun 23;22(1):516. doi: 10.1186/s12877-022-03072-w.
Impact factor: 3.921
Publication type: Paper in international publication
Authors: Davey, Vanessa; Castellano-Tejedor, Carmina; Perez, Laura M; Soto-Bagaria, Luis; Risco, Ester; Mazo, Maria Victoria; Gomez, Ana; Salvador, Daniel; Yanguas, Javier; Enfedaque, Maria B et al.
DOI: 10.1186/s12877-022-03072-w

Corrigendum: Dynamics of Emergency Cardiovascular Hospital Admissions and In-Hospital Mortality During the COVID-19 Pandemic: Time Series Analysis and Impact of Socioeconomic Factors.

PMID: 35757335
Journal: Frontiers in Cardiovascular Medicine
Year: 2022
Reference: Front Cardiovasc Med. 2022 Jun 9;9:935850. doi: 10.3389/fcvm.2022.935850. eCollection 2022.
Impact factor: 6.05
Publication type: Letter or abstract
Authors: Alvarez-Martin, Claudia; Ribera, Aida; Marsal, Josep Ramon; Perez-Hoyos, Santiago; Ferreira-Gonzalez, Ignacio; Mauri, Josepa; Lidon, Rosa M; Pijoan, Jose Ignacio; Romaguera, Rafael; Soriano-Colome, Toni et al.
DOI: 10.3389/fcvm.2022.935850

Impact of revascularization guided by functional testing in ischaemic cardiomyopathy.

PMID: 35781510
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2022
Reference: Eur Heart J Cardiovasc Imaging. 2022 Jul 4. pii: 6628344. doi: 10.1093/ehjci/jeac125.
Impact factor: 6.875
Publication type: Paper in international publication
Authors: Barrabes, Jose A; Aguade-Bruix, Santiago; Ferreira-Gonzalez, Ignacio; Ribera, Aida; Pizzi, Maria Nazarena; Herrador, Lorena; Rodenas-Alesina, Eduard; Romero-Farina, Guillermo; Jordan, Pablo; Espinet-Coll, Carina et al.
DOI: 10.1093/ehjci/jeac125

Predictors of Suicide Re-Attempt in a Spanish Adolescent Population after 12 Months' Follow-Up.

PMID: 35805225
Journal: International Journal of Environmental Research and Public Health
Year: 2022
Reference: Int J Environ Res Public Health. 2022 Jun 21;19(13). pii: ijerph19137566. doi: 10.3390/ijerph19137566.
Impact factor: 3.39
Publication type: Paper in international publication
Authors: Alvarez-Subiela, Xavier; Castellano-Tejedor, Carmina; Verge-Munoz, Mireia; Esnaola-Letemendia, Kike; Palao-Vidal, Diego; Villar-Cabeza, Francisco et al.
DOI: 10.3390/ijerph19137566

Walking While Talking and Prefrontal Oxygenation in Motoric Cognitive Risk Syndrome: Clinical and Pathophysiological Aspects.

PMID: 34744077
Journal: JOURNAL OF ALZHEIMERS DISEASE
Year: 2021
Reference: J Alzheimers Dis. 2021;84(4):1585-1596. doi: 10.3233/JAD-210239.
Impact factor: 4.472
Publication type: Paper in international publication
Authors: Udina, Cristina, Ayers, Emmeline, Inzitari, Marco, Verghese, Joe et al.
DOI: 10.3233/JAD-210239

The Gaze Fixation Assessed by Microperimetry: A Useful Tool for the Monitoring of the Cognitive Function in Patients with Type 2 Diabetes.

PMID: 34442342
Journal: Journal of Personalized Medicine
Year: 2021
Reference: J Pers Med. 2021 Jul 22;11(8). pii: jpm11080698. doi: 10.3390/jpm11080698.
Impact factor: 4.945
Publication type: Paper in international publication
Authors: Simo, Rafael, Ciudin, Andreea, Hernandez, Cristina, Castellano-Tejedor, Carmina, Vazquez-de Sebastian, Julia, Rojano-Toimil, Alba, Ortiz-Zuniga, Angel Michael, Simo-Servat, Olga et al.
DOI: 10.3390/jpm11080698

Analysis of Effectiveness and Psychological Techniques Implemented in mHealth Solutions for Middle-Aged and Elderly Adults with Type 2 Diabetes: A Narrative Review of the Literature.

PMID: 34207402
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Jun 18;10(12). pii: jcm10122701. doi: 10.3390/jcm10122701.
Impact factor: 4.242
Publication type: Review in international publication
Authors: Vazquez-de Sebastian, Julia, Ciudin, Andreea, Castellano-Tejedor, Carmina et al.
DOI: 10.3390/jcm10122701

Delirium symptoms duration and mortality in SARS-COV2 elderly: results of a multicenter retrospective cohort study.

PMID: 34176083
Journal: AGING CLINICAL AND EXPERIMENTAL RESEARCH
Year: 2021
Reference: Aging Clin Exp Res. 2021 Aug;33(8):2327-2333. doi: 10.1007/s40520-021-01899-8. Epub 2021 Jun 26.
Impact factor: 3.638
Publication type: Paper in international publication
Authors: Morandi, Alessandro, Rebora, Paola, Isaia, Gianluca, Grossi, Eleonora, Faraci, Bianca, Gentile, Simona, Bo, Mario, Valsecchi, Maria Grazia, Ghezzi, Nives, Miksza, Julia et al.
DOI: 10.1007/s40520-021-01899-8

How a Barcelona Post-Acute Facility became a Referral Center for Comprehensive Management of Subacute Patients With COVID-19.

PMID: 32674827
Journal: Journal of the American Medical Directors Association
Year: 2020
Reference: J Am Med Dir Assoc. 2020 Jul;21(7):954-957. doi: 10.1016/j.jamda.2020.06.015. Epub 2020 Jun 11.
Impact factor: 4.367
Publication type: Paper in international publication
Authors: Inzitari, Marco, Udina, Cristina, Len, Oscar, Ars, Joan, Arnal, Cristina, Badani, Hugo, Davey, Vanessa, Risco, Ester, Ayats, Pere, de Andres, Ana M et al.
DOI: 10.1016/j.jamda.2020.06.015

Glutathione Serum Levels and Rate of Multimorbidity Development in Older Adults.

PMID: 31086967
Journal: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
Year: 2020
Reference: J Gerontol A Biol Sci Med Sci. 2020 May 22;75(6):1089-1094. doi: 10.1093/gerona/glz101.
Impact factor: 5.236
Publication type: Paper in international publication
Authors: Perez, Laura M, Hooshmand, Babak, Mangialasche, Francesca, Mecocci, Patrizia, Smith, A David, Refsum, Helga, Inzitari, Marco, Fratiglioni, Laura, Rizzuto, Debora, Calderon-Larranaga, Amaia et al.
DOI: 10.1093/gerona/glz101

Defining the characteristics of intermediate care models including transitional care: an international Delphi study.

PMID: 32430887
Journal: AGING CLINICAL AND EXPERIMENTAL RESEARCH
Year: 2020
Reference: Aging Clin Exp Res. 2020 Nov;32(11):2399-2410. doi: 10.1007/s40520-020-01579-z. Epub 2020 May 19.
Impact factor: 2.697
Publication type: Paper in international publication
Authors: Kieliszek, Magdalena, van der Vlegel-Brouwer, Wilma, Nelson, Michelle, Manas, Leocadio Rodriguez, Antoniadou, Eleftheria, Barriere, Francois, Lindblom, Sebastian, Park, Grace, Perez, Isidoro, Alguacil, Dolores et al.
DOI: 10.1007/s40520-020-01579-z

The role of physical exercise and rehabilitation in delirium.

PMID: 32297245
Journal: European Geriatric Medicine
Year: 2020
Reference: Eur Geriatr Med. 2020 Feb;11(1):83-93. doi: 10.1007/s41999-020-00290-6. Epub 2020 Feb 17.
Impact factor: 1.232
Publication type: Review in international publication
Authors: Udina, C, Perez, L M, Inzitari, M, Crespo, N, Britez, L, Garcia-Salmones, M, Gual, N et al.
DOI: 10.1007/s41999-020-00290-6

Home as a Place for Care of the Oldest Stroke Patients: A Pilot from the Catalan Stroke Program.

PMID: 31018014
Journal: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
Year: 2019
Reference: J Am Geriatr Soc. 2019 Sep;67(9):1979-1981. doi: 10.1111/jgs.15944. Epub 2019 Apr 24.
Impact factor: 4.113
Publication type: Letter whit IF
Authors: Mas, Miquel A, Gamez, Sara, Inzitari, Marco, Ribera, Aida, Santaeugenia, Sebastia J, Gallofre, Miquel, Closa, Conxita et al.
DOI: 10.1111/jgs.15944

[Hospital-at-home Integrated Care Programme tailored to older patients with disabling acute processes: identification of prognostic factors].

PMID: 30792139
Journal: Revista espanola de geriatria y gerontologia
Year: 2019
Reference: Rev Esp Geriatr Gerontol. 2019 May - Jun;54(3):136-142. doi: 10.1016/j.regg.2018.11.005. Epub 2019 Feb 18.
Impact factor: 0
Publication type: Paper in national publication
Authors: Mas, Miquel Angel, Miralles, Ramon, Renom-Guiteras, Anna, Duran, Xavier, Inzitari, Marco et al.
DOI: 10.1016/j.regg.2018.11.005

Nutritional Status and Functional Outcomes in Older Adults Admitted to Geriatric Rehabilitations: The SAFARI Study.

PMID: 30676263
Journal: JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION
Year: 2019
Reference: J Am Coll Nutr. 2019 Jul;38(5):441-446. doi: 10.1080/07315724.2018.1541427. Epub 2019 Jan 24.
Impact factor: 2.08
Publication type: Paper in international publication
Authors: Lelli, Diana, Calle, Alicia, Perez, Laura Monica, Onder, Graziano, Morandi, Alessandro, Ortolani, Elena, Colominas, Miriam, Pedone, Claudio, Inzitari, Marco et al.
DOI: 10.1080/07315724.2018.1541427

25(OH) vitamin D and functional outcomes in older adults admitted to rehabilitation units: the safari study.

PMID: 30652217
Journal: OSTEOPOROSIS INTERNATIONAL
Year: 2019
Reference: Osteoporos Int. 2019 Apr;30(4):887-895. doi: 10.1007/s00198-019-04845-7. Epub 2019 Jan 16.
Impact factor: 3.819
Publication type: Paper in international publication
Authors: Inzitari, M, Lelli, D, Perez Bazan, L M, Calle Egusquiza, A, Onder, G, Morandi, A, Ortolani, E, Mesas Cervilla, M, Pedone, C et al.
DOI: 10.1007/s00198-019-04845-7

Hospital-at-home Integrated Care Programme for the management of disabling health crises in older patients: comparison with bed-based Intermediate Care.

PMID: 28655169
Journal: AGE AND AGEING
Year: 2017
Reference: Age Ageing. 2017 Nov 1;46(6):925-931. doi: 10.1093/ageing/afx099.
Impact factor: 4.282
Publication type: Paper in international publication
Authors: Santaeugenia, Sebastia J, Miralles, Ramon, Sabate, Sergi, Inzitari, Marco, Mas, Miquel A et al.
DOI: 10.1093/ageing/afx099

[Management of avoidable acute transfers from an intermediate care geriatric facility to acute hospitals: critical aspects of an intervention protocol].

PMID: 26948303
Journal: Revista espanola de geriatria y gerontologia
Year: 2017
Reference: Rev Esp Geriatr Gerontol. 2017 Mar - Apr;52(2):75-79. doi: 10.1016/j.regg.2015.12.007. Epub 2016 Mar 3.
Impact factor: 0
Publication type: Paper in national publication
Authors: Colprim, Daniel, Casco, Monica, Malumbres, Jennifer, Rodriguez, Gines, Inzitari, Marco et al.
DOI: 10.1016/j.regg.2015.12.007

[Do you measure gait speed in your daily clinical practice? A review].

PMID: 26908071
Journal: Revista espanola de geriatria y gerontologia
Year: 2017
Reference: Rev Esp Geriatr Gerontol. 2017 Jan - Feb;52(1):35-43. doi: 10.1016/j.regg.2015.12.010. Epub 2016 Feb 20.
Impact factor: 0
Publication type: Review in national publication
Authors: Inzitari, Marco, Calle, Alicia, Esteve, Anna, Casas, Alvaro, Torrents, Nuria, Martinez, Nicolas et al.
DOI: 10.1016/j.regg.2015.12.010

Hospital-at-home Integrated Care Program for Older Patients With Orthopedic Processes: An Efficient Alternative to Usual Hospital-Based Care.

PMID: 28578883
Journal: Journal of the American Medical Directors Association
Year: 2017
Reference: J Am Med Dir Assoc. 2017 Sep 1;18(9):780-784. doi: 10.1016/j.jamda.2017.04.006. Epub 2017 May 31.
Impact factor: 5.775
Publication type: Paper in international publication
Authors: Closa, Conxita, Mas, Miquel A, Santaeugenia, Sebastia J, Inzitari, Marco, Ribera, Aida, Gallofre, Miquel et al.
DOI: 10.1016/j.jamda.2017.04.006

Hospital-at-home integrated care programme for older patients with orthopaedic conditions: Early community reintegration maximising physical function.

PMID: 27105701
Journal: MATURITAS
Year: 2016
Reference: Maturitas. 2016 Jun;88:65-9. doi: 10.1016/j.maturitas.2016.03.005. Epub 2016 Mar 11.
Impact factor: 3.12
Publication type: Paper in international publication
Authors: Inzitari, Marco, Mas, Miquel Angel, Closa, Conxita, Santaeugenia, Sebastia J, Gallofre, Miquel, Ribera, Aida et al.
DOI: 10.1016/j.maturitas.2016.03.005

Daily Function as Predictor of Dementia in Cognitive Impairment, No Dementia (CIND) and Mild Cognitive Impairment (MCI): An 8-Year Follow-Up in the ILSA Study.

PMID: 27163817
Journal: JOURNAL OF ALZHEIMERS DISEASE
Year: 2016
Reference: J Alzheimers Dis. 2016 May 7;53(2):505-15. doi: 10.3233/JAD-160087.
Impact factor: 3.92
Publication type: Paper in international publication
Authors: Di Carlo, Antonio, Baldereschi, Marzia, Lamassa, Maria, Bovis, Francesca, Inzitari, Marco, Solfrizzi, Vincenzo, Panza, Francesco, Galluzzo, Lucia, Scafato, Emanuele, Inzitari, Domenico et al.
DOI: 10.3233/JAD-160087

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News

The two centres call on people with a diagnosis of cancer over 65-years-old and living in Barcelona to participate in the trial.

The Barcelona Aging coLLaboratory (BALL) aims to create innovative solutions, with the participation of end users, to improve quality of life and health and social care for the elderly.

Entre els projectes es troben 12 investigacions on participen investigadors i investigadores de Vall d’Hebron.

Vols participar en els nostres estudis? Busquem voluntaris

PROFIT study: It evaluates the benefits of physical exercise in people over 65 who suffer from lung, prostate or gastrointestinal cancer.

FRONTSTAGE study: It evaluates the effect of physical exercise on the physical and cognitive function of elderly people with mild mobility and memory problems.

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