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Rheumatology

The Rheumatology Research Group (GRR) is focused on translational research in immunity-mediated inflammatory diseases (IMIDA), mainly in the area of rheumatology. The GRR is a multidisciplinary group made up of clinical specialists, biologists, bioinformaticians and laboratory technicians. The different research lines of the GRR emphasize the use of high-performance technologies for the study at the cellular and molecular level of the immununopathology of IMIDA, mainly chronic inflammatory arthritis and autoimmune systemic diseases.

At the clinical level, we have developed lines of research in very diverse areas of rheumatology, including chronic inflammatory arthritis (rheumatoid arthritis, spondyloarthropathies), systemic autoimmune diseases (lupus, myositis, Sjögren's syndrome), the study of musculoskeletal imaging, pediatric rheumatology (juvenile idiopathic arthritis, autoimmune systemic diseases, autoinflammatory syndromes), central sensitization syndromes and the study of bone metabolism. One of the main objectives of the GRR is the coordination of basic and clinical research to accelerate the transfer of knowledge to clinical practice and thus improve the quality of life of patients.

Team

Sara Marsal Barril

Sara Marsal Barril

Head of group
Rheumatology
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Cristina Solé Marce

Cristina Solé Marce

Main researcher
Rheumatology
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Jesus Castro Marrero

Jesus Castro Marrero

Postdoctoral researcher
Rheumatology
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Josefina Cortes  Hernandez

Josefina Cortes Hernandez

Main researcher
Rheumatology
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Juan Jose De Agustin De Oro

Juan Jose De Agustin De Oro

Senior researcher
Rheumatology
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Maria America Lopez Lasanta

Maria America Lopez Lasanta

Main researcher
Rheumatology
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Sara Marsal Barril

Sara Marsal Barril

Head of group
Rheumatology
Read more
Cristina Solé Marce

Cristina Solé Marce

Main researcher
Rheumatology
Read more
Jesus Castro Marrero

Jesus Castro Marrero

Postdoctoral researcher
Rheumatology
Read more
Josefina Cortes  Hernandez

Josefina Cortes Hernandez

Main researcher
Rheumatology
Read more
Juan Jose De Agustin De Oro

Juan Jose De Agustin De Oro

Senior researcher
Rheumatology
Read more
Maria America Lopez Lasanta

Maria America Lopez Lasanta

Main researcher
Rheumatology
Read more

Projects

TBC

IP: Maria America Lopez Lasanta
Collaborators: -
Funding agency: AbbVie Ltd.
Funding: 15000
Reference: FER/LOPEZ/2023
Duration: 15/10/2025 - 15/12/2026

"Projecte BISC: bioètica i inclusió del sexe cromosòmic en l'atenció sanitària"

IP: Cristina Solé Marce
Collaborators: -
Funding agency: Fundació Víctor Grífols i Lucas
Funding: 6000
Reference: GRIFOLS/BECA/SOLE/2025
Duration: 12/11/2025 - 11/11/2026

Lupus Eritematoso Sistémico: de la fase preclinica a la enfermedad establecida. Caracterización molecular de las diferentes etapas e identificación de factores de riesgo de progresión temprana

IP: Josefina Cortes Hernandez
Collaborators: Maria Royo Lopez
Funding agency: Instituto de Salud Carlos III
Funding: 276156.25
Reference: PI24/01743
Duration: 01/01/2025 - 31/12/2027

Implementación de un proceso asistencial automatizado para el diagnóstico precoz de artritis psoriásica en pacientes con psoriásis: Proyecto multidisciplinar entre atención primaria y atención hospitalaria

IP: María Alba Erra Duran
Collaborators: Juan Jose De Agustin De Oro, Jordi Mollet Sánchez, Yolima Cossio Gil, Emmanuel Giménez García, Gloria Aparicio Español, Luis Coronel Tarancon
Funding agency: Instituto de Salud Carlos III
Funding: 57500
Reference: PI25/01718
Duration: 01/01/2026 - 31/12/2028

Thesis

Miositis associada a càncer: estratègies de cribratge i caracterització immunogenòmica.

PhD student: Albert Gil Vila
Director/s: Ernesto Trallero Araguas, Albert Selva O'Callaghan
University:
Year: 2024

Adherència al tractament a l'Artritis Idiopàtica Juvenil en una cohort catalana. Validació dels qüestionaris PARQ i CARQ al nostre entorn

PhD student: Estefania Moreno Ruzafa
Director/s: Sara Marsal Barril
University:
Year: 2024

Characterization of pathogenic immune mechanisms in oligoarticular juvenile idiopathic arthritis applying single-cell transcriptomics and proteomics

PhD student: Mireia Lopez Corbeto
Director/s: Sara Marsal Barril, Antonio Julia Cano
University:
Year: 2023

Utilidad del Q Sofa y la procalcitonina para el diagnóstico precoz del paciente séptico en urgencias

PhD student: Milagros Tessy Calizaya Vargas
Director/s: Tomás Fernández de Sevilla Ribosa, Tomás Fernández de Sevilla Ribosa
University: Universitat Autònoma de Barcelona
Year: 2022

Identification of differential biological mechanisms between pregnancy and postpartum in Rheumatoid Arthritis

PhD student: Andrea Pluma Sanjurjo
Director/s: Sara Marsal Barril
University:
Year: 2022

Prevalencia de la sensibilidad al gluten no celíaca y valoración de la respuesta a una dieta sin gluten en una cohorte de pacientes con fibromialgia.

PhD student: Miriam Almirall Bernabé
Director/s: Sara Marsal Barril, Francesc Casellas Jordá
University:
Year: 2022

Exosomas urinarios: Identificación de biomarcadores de respuesta clínica en la nefritis lúpica

PhD student: Eloy Garcia Vives
Director/s: Josefina Cortes Hernandez
University: Universidad Autònoma de Barcelona
Year: 2019

Factores predictores de la respuesta clínica al tratamiento con fármacos biológicos en la artritis reumatoide

PhD student: Maria Alba Erra Duran, Maria Alba Erra Duran, Maria Alba Erra Duran
Director/s: Vicenç Fonollosa Pla
University: Universidad Autònoma de Barcelona
Year: 2017

Nuevas estrategias en el diagnóstico del cáncer asociado a las dermatomiositis y polimiositis.

PhD student: Ernesto Trallero Araguas
Director/s: Albert Selva O'Callaghan, Moisés Labrador Horrillo
University: Universidad Autònoma de Barcelona
Year: 2011

Genomic approaches for the indentification of risk loci for Rheumatoid Arthritis.

PhD student: Antonio Julia Cano
Director/s: Sara Marsal Barril
University: Universidad Autònoma de Barcelona
Year: 2010

Blog

News

The new therapeutic strategy aims at maintaining the efficacy of thalidomide while avoiding its main systemic adverse effects.

The event, held as part of World Lupus Day, incorporated the perspective of people living with the disease to address the challenges associated with lupus.

The global biopharmaceutical company UCB has acquired the data and clinical knowledge business of IMIDomics, a spin-off of the Vall d’Hebron Institute of Research (VHIR).