About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
PMID: 33884956 Journal: JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY Year: 2021 Reference: J Investig Allergol Clin Immunol. 2021 Apr 22:0. doi: 10.18176/jiaci.0696. Impact factor: 7.033 Publication type: Paper in international publication Authors: Vila, L, Ibanez-Sandin, M D, Rodriguez Del Rio, P, Alvarado, M I, Garcia, B E, Garriga-Baraut, T, Reche Frutos, M, Escudero, C, Ramirez, A, Marchan-Martin, E et al. DOI: 10.18176/jiaci.0696
PMID: 33880889 Journal: CLINICAL AND EXPERIMENTAL ALLERGY Year: 2021 Reference: Clin Exp Allergy. 2021 Aug;51(8):1033-1045. doi: 10.1111/cea.13884. Epub 2021 May 11. Impact factor: 5.018 Publication type: Paper in international publication Authors: Bousquet, Jean, Schroder-Bernhardi, Detlef, Bachert, Claus, Costa, Elisio M, Czarlewski, Wienczyslawa, Devillier, Philippe, Fonseca, Joao, Klimek, Ludger, Kuna, Piotr, Lourenco, Olga et al. DOI: 10.1111/cea.13884
PMID: 33867271 Journal: Reumatologia clinica Year: 2021 Reference: Reumatol Clin (Engl Ed). 2021 Apr 15. pii: S1699-258X(21)00065-6. doi: 10.1016/j.reuma.2021.01.007. Impact factor: 0 Publication type: Paper in national publication Authors: Barbadillo, Carmen, Sivera, Francisca, Belzunegui, Joaquin, Perez Gomez, Ana, Gomez Gomez, Alejandro, Delgado-Frias, Esmeralda, Pego-Reigosa, Jose Maria, Joven, Beatriz, Ibanez, Monica, Martinez-Gonzalez, Olga et al. DOI: 10.1016/j.reuma.2021.01.007
PMID: 33314628 Journal: Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology Year: 2021 Reference: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 May;13(3):e1684. doi: 10.1002/wnan.1684. Epub 2020 Dec 13. Impact factor: 9.182 Publication type: Review in international publication Authors: Abasolo, Ibane, Seras-Franzoso, Joaquin, Molto-Abad, Marc, Diaz-Riascos, Vanessa, Corchero, Jose Luis, Pintos-Morell, Guillem, Schwartz, Simo Jr et al. DOI: 10.1002/wnan.1684
PMID: 31995656 Journal: ALLERGY Year: 2020 Reference: Allergy. 2020 Jul;75(7):1672-1688. doi: 10.1111/all.14204. Epub 2020 Mar 22. Impact factor: 8.706 Publication type: Paper in international publication Authors: Fokkens, Wytske J, Bedard, Annabelle, Anto, Josep M, Fonseca, Joao A, Arnavielhe, Sylvie, Bachert, Claus, Bedbrook, Anna, Bindslev-Jensen, Carsten, Bosnic-Anticevich, Sinthia, Cardona, Victoria et al. DOI: 10.1111/all.14204
PMID: 31977447 Journal: Current Opinion in Allergy and Clinical Immunology Year: 2020 Reference: Curr Opin Allergy Clin Immunol. 2020 Jun;20(3):248-252. doi: 10.1097/ACI.0000000000000625. Impact factor: 3.246 Publication type: Review in international publication Authors: Cardona, Victoria, Guilarte, Mar, Labrador-Horrillo, Moises et al. DOI: 10.1097/ACI.0000000000000625
PMID: 31969223 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2020 Reference: Clin Exp Rheumatol. 2020 May-Jun;38 Suppl 125(3):106-114. Epub 2020 Jan 14. Impact factor: 3.319 Publication type: Paper in international publication Authors: Iniesta Arandia, Nerea, Espinosa, Gerard, Tolosa Vilella, Carles, Guillen Del Castillo, Alfredo, Rubio Rivas, Manuel, Freire, Mayka, Vargas Hitos, Jose Antonio, Todoli Parra, Jose Antonio, Rodriguez Carballeira, Monica, Marin Ballve, Adela et al. DOI:
PMID: 31963773 Journal: International Journal of Environmental Research and Public Health Year: 2020 Reference: Int J Environ Res Public Health. 2020 Jan 19;17(2). pii: ijerph17020634. doi: 10.3390/ijerph17020634. Impact factor: 2.849 Publication type: Paper in international publication Authors: Serrat, Mayte, Sanabria-Mazo, Juan P, Garcia-Troiteiro, Elna, Fontcuberta, Anna, Mateo-Canedo, Corel, Almirall, Miriam, Feliu-Soler, Albert, Mendez-Ulrich, Jorge Luis, Sanz, Antoni, Luciano, Juan V et al. DOI: 10.3390/ijerph17020634
PMID: 31113593 Journal: Annals of Hepatology Year: 2019 Reference: Ann Hepatol. 2019 Jan - Feb;18(1):215-219. doi: 10.5604/01.3001.0012.7916. Impact factor: 1.895 Publication type: Paper in international publication Authors: Martinez-Valle, Fernando, Riveiro-Barciela, Mar, Salcedo, Maria-Teresa, Merino-Casabiel, Xavier, Fernandez-Codina, Andreu, Torres, Ines de, Esteban, Rafael, Buti, Maria et al. DOI: 10.5604/01.3001.0012.7916
PMID: 30911161 Journal: NATURE GENETICS Year: 2019 Reference: Nat Genet. 2019 Apr;51(4):659-674. doi: 10.1038/s41588-019-0364-4. Epub 2019 Mar 25. Impact factor: 25.455 Publication type: Paper in international publication Authors: Mahajan, Milind C, Kramer, Robin, Domenici, Enrico, Gamazon, Eric R, Purcell, Shaun, Demontis, Ditte, Borglum, Anders D, Walters, James T R, O'Donovan, Michael C, Sullivan, Patrick et al. DOI: 10.1038/s41588-019-0364-4
PMID: 31086353 Journal: NATURE GENETICS Year: 2019 Reference: Nat Genet. 2019 Jun;51(6):1068. doi: 10.1038/s41588-019-0435-6. Impact factor: 25.455 Publication type: Letter or abstract Authors: Gamazon, Eric R, Huckins, Laura M, Dobbyn, Amanda, Ruderfer, Douglas M, Hoffman, Gabriel, Wang, Weiqing, Pardinas, Antonio F, Rajagopal, Veera M, Als, Thomas D, T Nguyen, Hoang et al. DOI: 10.1038/s41588-019-0435-6
PMID: 31081519 Journal: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING Year: 2019 Reference: Eur J Nucl Med Mol Imaging. 2019 Jul;46(8):1626-1632. doi: 10.1007/s00259-019-04339-y. Epub 2019 May 12. Impact factor: 7.182 Publication type: Paper in international publication Authors: Martinez-Valle, Fernando, Navales, Ignacio, Loureiro-Amigo, Jose, Solans-Laque, Roser, Simo-Perdigo, Marc, Mestre-Torres, Jaume et al. DOI: 10.1007/s00259-019-04339-y
PMID: 29314762 Journal: International Journal of Rheumatic Diseases Year: 2018 Reference: Int J Rheum Dis. 2018 Feb;21(2):487-496. doi: 10.1111/1756-185X.13255. Epub 2018 Jan 5. Impact factor: 2.423 Publication type: Paper in international publication Authors: Redondo-Benito, Ada, Curran, Adrian, Villar-Gomez, Ana, Trallero-Araguas, Ernesto, Fernandez-Codina, Andreu, Pinal-Fernandez, Iago, Rodrigo-Pendas, Jose Angel, Selva-O'Callaghan, Albert et al. DOI: 10.1111/1756-185X.13255
PMID: 28600902 Journal: ALLERGY Year: 2018 Reference: Allergy. 2018 Jan;73(1):77-92. doi: 10.1111/all.13218. Epub 2017 Aug 24. Impact factor: 6.048 Publication type: Paper in international publication Authors: De Feo, G, Bousquet, J, Agache, I, Aliberti, M R, Angles, R, Annesi-Maesano, I, Anto, J M, Arnavielhe, S, Asayag, E, Bacci, E et al. DOI: 10.1111/all.13218
PMID: 28249725 Journal: JOINT BONE SPINE Year: 2018 Reference: Joint Bone Spine. 2018 Jan;85(1):119. doi: 10.1016/j.jbspin.2017.02.008. Epub 2017 Feb 27. Impact factor: 3.304 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Simo, Marc, Solans-Laque, Roser, Martinez-Valle, Fernando et al. DOI: 10.1016/j.jbspin.2017.02.008
PMID: 28229826 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2017 Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):40-47. Epub 2017 Feb 6. Impact factor: 2.634 Publication type: Paper in international publication Authors: Rubio-Rivas, Manuel, Simeon-Aznar, Carmen Pilar, Velasco, Cesar, Mari-Alfonso, Begona, Espinosa, Gerard, Corbella, Xavier, Colunga-Arguelles, Dolores, Egurbide-Arberas, Maria Victoria, Ortego-Centeno, Norberto, Freire, Mayka et al. DOI:
PMID: 28225490 Journal: MEDICINE Year: 2017 Reference: Medicine (Baltimore). 2017 Feb;96(8):e6083. doi: 10.1097/MD.0000000000006083. Impact factor: 1.803 Publication type: Paper in international publication Authors: Solans-Laque, Roser, Fraile, Guadalupe, Rodriguez-Carballeira, Monica, Caminal, Luis, Castillo, Maria J, Martinez-Valle, Ferran, Saez, Luis, Rios, Juan J, Solanich, Xavier, Oristrell, Joaquim et al. DOI: 10.1097/MD.0000000000006083
PMID: 27043027 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2017 Reference: Rheumatol Int. 2017 Jan;37(1):177. doi: 10.1007/s00296-016-3470-y. Impact factor: 1.824 Publication type: Letter or abstract Authors: Fernandez-Codina, Andreu, Simeon-Aznar, Carmen Pilar, Pinal-Fernandez, Iago, Rodriguez-Palomares, Jose, Pizzi, Maria Nazarena, Hidalgo, Cristina Eve, Guillen-Del Castillo, Alfredo, Prado-Galbarro, Francisco Javier, Sarria-Santamera, Antonio, Fonollosa-Pla, Vicent et al. DOI: 10.1007/s00296-016-3470-y
PMID: 26497313 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2017 Reference: Rheumatol Int. 2017 Jan;37(1):75-84. doi: 10.1007/s00296-015-3382-2. Epub 2015 Oct 25. Impact factor: 1.824 Publication type: Paper in international publication Authors: Fernandez-Codina, Andreu, Simeon-Aznar, Carmen Pilar, Pinal-Fernandez, Iago, Rodriguez-Palomares, Jose, Pizzi, Maria Nazarena, Hidalgo, Cristina Eve, Del Castillo, Alfredo Guillen, Prado-Galbarro, Francisco Javier, Sarria-Santamera, Antonio, Fonollosa-Pla, Vicent et al. DOI: 10.1007/s00296-015-3382-2
PMID: 24252627 Journal: Reumatología clinica Year: 2014 Reference: Reumatol Clin. 2014 Mar-Apr;10(2):85-8. doi: 10.1016/j.reuma.2013.05.012. Epub 2013 Nov 17. Impact factor: Publication type: Letter or abstract Authors: Grados, Dolors, Marsal, Sara, Olive, Alejandro et al. DOI: 10.1016/j.reuma.2013.05.012
PMID: 23830554 Journal: MED CLIN-BARCELONA Year: 2014 Reference: Med Clin (Barc). 2014 Apr 22;142(8):360-4. doi: 10.1016/j.medcli.2013.04.038. Epub 2013 Jul 3. Impact factor: 1.252 Publication type: Paper in national publication Authors: Ordi-Ros, Josep, Cosiglio, Francisco Javier et al. DOI: 10.1016/j.medcli.2013.04.038
PMID: 23463692 Journal: ANN RHEUM DIS Year: 2014 Reference: Ann Rheum Dis. 2014 Apr;73(4):662-7. doi: 10.1136/annrheumdis-2012-202708. Epub 2013 Mar 5. Impact factor: 9.27 Publication type: Paper in international publication Authors: Ozen, Seza, Demirkaya, Erkan, Amaryan, Gayane, Kone-Paut, Isabelle, Polat, Adem, Woo, Pat, Uziel, Yosef, Modesto, Consuelo, Finetti, Martina, Quartier, Pierre et al. DOI: 10.1136/annrheumdis-2012-202708
PMID: 24646463 Journal: MEDICINE Year: 2014 Reference: Medicine (Baltimore). 2014 Mar;93(2):73-81. doi: 10.1097/MD.0000000000000018. Impact factor: 4.867 Publication type: Paper in national publication Authors: Alba, Marco A, Velasco, Cesar, Simeon, Carmen Pilar, Fonollosa, Vicent, Trapiella, Luis, Egurbide, Maria Victoria, Saez, Luis, Castillo, Maria Jesus, Callejas, Jose Luis, Camps, Maria Teresa et al. DOI: 10.1097/MD.0000000000000018
PMID: 22294626 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2012 Reference: Ann Rheum Dis. 2012 Jun;71(6):993-6. doi: 10.1136/annrheumdis-2011-200871. Epub 2012 Jan 30. Impact factor: 8.727 Publication type: Paper in international publication Authors: , , , , , , et al. DOI: 10.1136/annrheumdis-2011-200871
PMID: 21992597 Journal: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY Year: 2012 Reference: Am J Reprod Immunol. 2012 Feb;67(2):140-151. doi: 10.1111/j.1600-0897.2011.01072.x. Epub 2011 Oct 13. Impact factor: 3.05 Publication type: Paper in international publication Authors: , , , , , et al. DOI: 10.1111/j.1600-0897.2011.01072.x
PMID: 22045834 Journal: JOURNAL OF RHEUMATOLOGY Year: 2012 Reference: J Rheumatol. 2012 Jan;39(1):112-118. Epub 2011 Nov 1. Impact factor: 3.695 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.3899/jrheum.110235
PMID: 22087014 Journal: RHEUMATOLOGY Year: 2012 Reference: Rheumatology (Oxford). 2012 Jan;51(1):52-9. Epub 2011 Nov 15. Impact factor: 4.058 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1093/rheumatology/ker335
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.
