About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.
Cells that are chronically exposed to inflammatory signals are more prone to aging than those which are not exposed to such signals. Human vascular endothelial cell (HUVEC) primary cultures activated with TNF-alpha probably increase the expression of ICAM and VCAM, synthesize ROS, and express senescence markers. It is not known what the principal intracellular pathway is (although it is thought that STAT may play a role) and it is unknown if one or more proinflammatory cytokines are needed to activate NF-KB. We are trying to find out the role that IFN-alpha and/or IL-6 and IL-1B may have on the aging inflammatory phenomena and we aim at detecting the intracellular signal pathways (STAT). We are also working on the characterization of the genes involved in these abnormal biologic responses.
IP: Jaume Alijotas Reig
This study, carried out along with researchers from the Hospital del Mar and from the "Institut Municipal d'Investigació Mèdica", aims at correlating the expression of SLRPs and MMP-13 with the severity of cutaneous involvement, hand dysfunctional capacity, capillaroscopy patterns, and cutaneous ultrasonography of patients affected with diffuse scleroderma in different evolutive stages of the disease.
IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla
This study aims at detecting the prevalence of specific IgE in polisensitized patients towards pollen in Barcelona by means of the "component resolved diagnosis" technique from ISAC® (IgE specific microarray).
IP: Victòria Cardona Dahl
The study aims to investigate the risk factors for ischemic complications in patients with GCA, and the role that some endothelial growth factors may play in its development. This study is coordinated by Dr. Gonzalez Gay from University Hospital of Valdecilla, Santander.
IP: Roser Solans Laque
PMID: 37919733 Journal: Environmental Health Year: 2023 Reference: Environ Health. 2023 Nov 2;22(1):77. doi: 10.1186/s12940-023-01028-0. Impact factor: Publication type: Paper in international publication Authors: Alemany, Laia; Alguacil, Juan; Ansotegui, Ignacio J; Benavente, Yolanda; Bosch, Francesc Xavier; Brunet, Joan; Caminati, Marco; Campbell, Dianne E; Cano, Victor; Cardona, Victoria et al. DOI: 10.1186/s12940-023-01028-0
PMID: 37950760 Journal: JOURNAL OF NEUROLOGY Year: 2023 Reference: J Neurol. 2023 Nov 11. doi: 10.1007/s00415-023-12076-4. Impact factor: Publication type: Paper in international publication Authors: Aggarwal, Rohit; Amato, Anthony A; Andersson, Helena; Andrade-Ortega, Lilia; Ascherman, Dana; Attarian, Shahram; Beloribi-Djefaflia, Sadia; Benveniste, Olivier; Bonello-Palot, Nathalie; Callen, Jeffrey P et al. DOI: 10.1007/s00415-023-12076-4
PMID: 37978852 Journal: Multiple Sclerosis Journal Year: 2023 Reference: Mult Scler. 2023 Nov 18:13524585231205962. doi: 10.1177/13524585231205962. Impact factor: Publication type: Paper in international publication Authors: Acosta-Herrera, Marialbert; Alexandri, Nektaria; Brieva, Luis; Brochet, Bruno; Callejas, Jose L; Guillen-Del-Castillo, Alfredo; Hupperts, Raymond; Keller, Birgit; Kubala Havrdova, Eva; Langdon, Dawn et al. DOI: 10.1177/13524585231205962
PMID: 37995519 Journal: Cancer treatment and research communications Year: 2023 Reference: Cancer Treat Res Commun. 2023 Nov 1;37:100772. doi: 10.1016/j.ctarc.2023.100772. Impact factor: Publication type: Paper in international publication Authors: Ales Martinez, Jose Enrique; Alijotas-Reig, Jaume; Antolin Novoa, Silvia; Anunciacion-Llunell, Ariadna; de la Morena Barrio, Pilar; Echavarria Diaz-Guardamino, Isabel; Escriva-de-Romani, Santiago; Esteve-Valverde, Enrique; Garate, Zita; Gonzalez-Cortijo, Lucia et al. DOI: 10.1016/j.ctarc.2023.100772
PMID: 35432370 Journal: Frontiers in Immunology Year: 2022 Reference: Front Immunol. 2022 Mar 31;13:873019. doi: 10.3389/fimmu.2022.873019. eCollection 2022. Impact factor: 7.561 Publication type: Paper in international publication Authors: Olivera-Ardid, Sara, Bello-Gil, Daniel, Tuzikov, Alexander, Araujo, Ricardo N, Ferrero-Alves, Yara, Garcia Figueroa, Blanca Esther, Labrador-Horrillo, Moises, Garcia-Perez, Ana L, Bovin, Nicolai, Manez, Rafael et al. DOI: 10.3389/fimmu.2022.873019
PMID: 34147248 Journal: MEDICINA CLINICA Year: 2022 Reference: Med Clin (Barc). 2022 Apr 8;158(7):301-307. doi: 10.1016/j.medcli.2021.03.005. Epub 2021 May 6. Impact factor: 1.725 Publication type: Paper in national publication Authors: Cardona-Pascual, Ignacio, Berlana, David, Martinez-Valle, Ferran, Campany-Herrero, David, Montoro-Ronsano, Jose Bruno et al. DOI: 10.1016/j.medcli.2021.03.005
PMID: 34844023 Journal: Journal of Allergy and Clinical Immunology-In Practice Year: 2022 Reference: J Allergy Clin Immunol Pract. 2022 Apr;10(4):1020-1028. doi: 10.1016/j.jaip.2021.11.018. Epub 2021 Nov 26. Impact factor: 8.861 Publication type: Paper in international publication Authors: Garcia, M G, Laffond, E, Munoz-Bellido, F J, Nunez, R, Prior, N, Sala-Cunill, A, Saenz de San Pedro, B, Prieto-Garcia, A, Escudero, E, Castro, M et al. DOI: 10.1016/j.jaip.2021.11.018
PMID: 35396580 Journal: NATURE Year: 2022 Reference: Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Impact factor: 49.962 Publication type: Paper in international publication Authors: Fananas, Lourdes, Richards, Alexander L, Sidorenko, Julia, Wu, Yang, Zeng, Jian, Grove, Jakob, Kim, Minsoo, Li, Zhiqiang, Voloudakis, Georgios, Zhang, Wen et al. DOI: 10.1038/s41586-022-04434-5
PMID: 34397526 Journal: EUROPEAN JOURNAL OF ANAESTHESIOLOGY Year: 2021 Reference: Eur J Anaesthesiol. 2021 Sep 1;38(9):916-922. doi: 10.1097/EJA.0000000000001484. Impact factor: 4.33 Publication type: Paper in international publication Authors: Pardos-Gea, Josep, Alijotas-Reig, Jaume, Esteve-Valverde, Enrique, Ferrer-Oliveras, Raquel, Saez-Comet, Luis, Lefkou, Elmina, Mekinian, Arsene, Belizna, Cristina, Ruffatti, Amelia, Tincani, Angela et al. DOI: 10.1097/EJA.0000000000001484
PMID: 34386153 Journal: World Allergy Organization Journal Year: 2021 Reference: World Allergy Organ J. 2021 Jul 28;14(8):100569. doi: 10.1016/j.waojou.2021.100569. eCollection 2021 Aug. Impact factor: 4.084 Publication type: Review in international publication Authors: Ansotegui, Ignacio J, Gonzalez-Diaz, Sandra Nora, Bilo, Maria Beatrice, Cardona, Victoria, Park, Hae-Sim, Braschi, Maria Chiara, Macias-Weinmann, Alejandra, Piga, Mario A, Acuna-Ortega, Natalhie, Sanchez-Borges, Mario et al. DOI: 10.1016/j.waojou.2021.100569
PMID: 34377160 Journal: Therapeutic Advances in Musculoskeletal Disease Year: 2021 Reference: Ther Adv Musculoskelet Dis. 2021 Jul 27;13:1759720X211032457. doi: 10.1177/1759720X211032457. eCollection 2021. Impact factor: 5.346 Publication type: Review in international publication Authors: Kuwana, Masataka, Gil-Vila, Albert, Selva-O'Callaghan, Albert et al. DOI: 10.1177/1759720X211032457
PMID: 34359858 Journal: Cells Year: 2021 Reference: Cells. 2021 Jul 4;10(7). pii: cells10071688. doi: 10.3390/cells10071688. Impact factor: 6.6 Publication type: Paper in international publication Authors: Barbera, Joan Albert, Peinado, Victor I, Blanco, Isabel, Garcia-Lucio, Jessica, Del Pozo, Roberto, Garcia, Agustin Roberto, Ferrer, Elisabet, Crespo, Isabel, Rodriguez-Chiaradia, Diego A, Simeon-Aznar, Carmen Pilar et al. DOI: 10.3390/cells10071688
PMID: 31033198 Journal: ARTHRITIS CARE & RESEARCH Year: 2020 Reference: Arthritis Care Res (Hoboken). 2020 Jul;72(7):1001-1010. doi: 10.1002/acr.23912. Epub 2020 Jun 12. Impact factor: 4.056 Publication type: Paper in international publication Authors: Rodriguez-Carballeira, Monica, Rios-Blanco, Juan Jose, Fraile, Guadalupe, Saez-Comet, Luis, Martinez-Zapico, Aleida, Frutos, Begona, Solanich, Xavier, Fonseca-Aizpuru, Eva, Pasquau-Liano, Francisco, Zamora, Monica et al. DOI: 10.1002/acr.23912
PMID: 32553611 Journal: AUTOIMMUNITY REVIEWS Year: 2020 Reference: Autoimmun Rev. 2020 Aug;19(8):102583. doi: 10.1016/j.autrev.2020.102583. Epub 2020 Jun 14. Impact factor: 7.767 Publication type: Review in international publication Authors: Mahler, Michael, Roup, Fabrece, Beretta, Lorenzo, Simeon, Carmen Pilar, Guillen-Del-Castillo, Alfredo, Casas, Silva, Fritzler, Marvin J, Bentow, Chelsea, Hudson, Marie et al. DOI: 10.1016/j.autrev.2020.102583
PMID: 32558485 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2020 Reference: N Engl J Med. 2020 Oct 15;383(16):1522-1534. doi: 10.1056/NEJMoa2020283. Epub 2020 Jun 17. Impact factor: 74.699 Publication type: Paper in international publication Authors: My, Ilaria, Ellinghaus, David, Degenhardt, Frauke, Bujanda, Luis, Buti, Maria, Albillos, Agustin, Invernizzi, Pietro, Fernandez, Javier, Prati, Daniele, Baselli, Guido et al. DOI: 10.1056/NEJMoa2020283
PMID: 31033231 Journal: ARTHRITIS CARE & RESEARCH Year: 2020 Reference: Arthritis Care Res (Hoboken). 2020 Jun;72(6):822-828. doi: 10.1002/acr.23910. Epub 2020 May 14. Impact factor: 4.056 Publication type: Paper in international publication Authors: Nolla, Joan M, Fernandez-Carballido, Cristina, Martin-Martinez, Maria A, Garcia-Gomez, Carmen, Yoldi, Beatriz, Ramentol, Mercedes, Avila, Gabriela, Barril, Sara Marsal, Steiner, Martina, Munoz, Santiago et al. DOI: 10.1002/acr.23910
PMID: 30789151 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2019 Reference: Clin Exp Rheumatol. 2019 Sep-Oct;37(5):774-782. Epub 2019 Feb 15. Impact factor: 3.238 Publication type: Paper in international publication Authors: Garcia-Gomez, Carmen, Martin-Martinez, Maria A, Fernandez-Carballido, Cristina, Castaneda, Santos, Gonzalez-Juanatey, Carlos, Sanchez-Alonso, Fernando, Gonzalez-Fernandez, Maria J, Sanmarti, Raimon, Garcia-Vadillo, Jesus A, Fernandez-Gutierrez, Benjamin et al. DOI:
PMID: 30620291 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2019 Reference: Clin Exp Rheumatol. 2019 Sep-Oct;37(5):731-739. Epub 2019 Jan 3. Impact factor: 3.238 Publication type: Paper in international publication Authors: Martin-Martinez, Maria A, Castaneda, Santos, Gonzalez-Juanatey, Carlos, Sanchez-Alonso, Fernando, Garcia-Gomez, Carmen, Lopez-Gonzalez, Ruth, Babio-Herraiz, Jesus, Juan-Mas, Antonio, Sanchez-Gonzalez, Carmen O, Romera-Baures, Montserrat et al. DOI:
PMID: 31557429 Journal: NEW ENGLAND JOURNAL OF MEDICINE Year: 2019 Reference: N Engl J Med. 2019 Dec 5;381(23):2199-2208. doi: 10.1056/NEJMoa1906190. Epub 2019 Sep 26. Impact factor: 70.67 Publication type: Paper in international publication Authors: Heels-Ansdell, Diane, Thabane, Lehana, Walter, Stephen D, Devereaux, P J, HEALTH investigators, Guerra Farfan, Ernesto Melchor, Teixidor Serra, Jordi, Tomás Hernández, Jordi, Molero García, Vicent, Selga Marsà, Jordi et al. DOI: 10.1056/NEJMoa1906190
PMID: 31533337 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2019 Reference: Int J Mol Sci. 2019 Sep 17;20(18). pii: ijms20184601. doi: 10.3390/ijms20184601. Impact factor: 4.183 Publication type: Paper in international publication Authors: Torres-Salido, Maria Teresa, Sanchis, Mireia, Sole, Cristina, Moline, Teresa, Vidal, Marta, Vidal, Xavier, Sola, Anna, Hotter, Georgina, Ordi-Ros, Josep, Cortes-Hernandez, Josefina et al. DOI: 10.3390/ijms20184601
PMID: 29965856 Journal: CURRENT OPINION IN RHEUMATOLOGY Year: 2018 Reference: Curr Opin Rheumatol. 2018 Nov;30(6):630-636. doi: 10.1097/BOR.0000000000000535. Impact factor: 4.277 Publication type: Paper in international publication Authors: Selva-O'Callaghan, Albert, Martinez-Gomez, Xavier, Trallero-Araguas, Ernesto, Pinal-Fernandez, Iago et al. DOI: 10.1097/BOR.0000000000000535
PMID: 29241876 Journal: MEDICINA CLINICA Year: 2018 Reference: Med Clin (Barc). 2018 Jul 13;151(1):18-25. doi: 10.1016/j.medcli.2017.10.034. Epub 2017 Dec 11. Impact factor: 1.168 Publication type: Review in national publication Authors: Martinez-Valle, Fernando, Orozco-Galvez, Olimpia, Fernandez-Codina, Andreu et al. DOI: 10.1016/j.medcli.2017.10.034
PMID: 29930757 Journal: Oncotarget Year: 2018 Reference: Oncotarget. 2018 Jun 5;9(43):27151-27170. doi: 10.18632/oncotarget.25502. eCollection 2018 Jun 5. Impact factor: 0 Publication type: Paper in international publication Authors: Tusell, Laura, Dominguez, Daniel, Bernal, Aina, Molto-Abad, Marc et al. DOI: 10.18632/oncotarget.25502
PMID: 29931516 Journal: CLINICAL RHEUMATOLOGY Year: 2018 Reference: Clin Rheumatol. 2018 Aug;37(8):2303-2304. doi: 10.1007/s10067-018-4179-y. Impact factor: 2.141 Publication type: Letter or abstract Authors: Callejas Moraga, E, Calvo, E, Carbonell, C, Castillo, M J, Chamorro, A J, Colunga, D, Corbella, X, Egurbide, M V, Espinosa, G, Fonollosa, V et al. DOI: 10.1007/s10067-018-4179-y
PMID: 28980905 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2017 Reference: Clin Exp Rheumatol. 2017 Sep-Oct;35 Suppl 106(4):89-97. Epub 2017 Sep 18. Impact factor: 2.634 Publication type: Review in international publication Authors: Marin Ballve, Adela, Pla Salas, Xavier, Madronero Vuelta, Ana Belen, Ruiz Munoz, Manuel, Fonollosa Pla, Vicent, Simeon Aznar, Carmen Pilar, Rios Blanco, Juan Jose, Vargas Hitos, Jose Antonio, Saez Comet, Luis, Egurbide Arberas, Maria Victoria et al. DOI:
PMID: 28934835 Journal: RHEUMATOLOGY Year: 2017 Reference: Rheumatology (Oxford). 2017 Apr 1;56(4):628. doi: 10.1093/rheumatology/kew415. Impact factor: 4.818 Publication type: Paper in international publication Authors: Pardos-Gea, Jose et al. DOI: 10.1093/rheumatology/kew415
PMID: 28918450 Journal: RHEUMATOLOGY INTERNATIONAL Year: 2017 Reference: Rheumatol Int. 2017 Nov;37(11):1817-1823. doi: 10.1007/s00296-017-3814-2. Epub 2017 Sep 16. Impact factor: 1.824 Publication type: Paper in international publication Authors: Sellas I Fernandez, Agusti, Juanola Roura, Xavier, Alonso Ruiz, Alberto, Rosas, Jose, Medina Luezas, Julio, Collantes Estevez, Eduardo, Abad Hernandez, Miguel Angel, Carrasco Benitez, Virginia, Fisac, Cesar et al. DOI: 10.1007/s00296-017-3814-2
PMID: 28856836 Journal: CLINICAL AND EXPERIMENTAL ALLERGY Year: 2017 Reference: Clin Exp Allergy. 2017 Sep;47(9):1108-1114. doi: 10.1111/cea.12973. Impact factor: 5.264 Publication type: Editorail in international publication Authors: Demoly, P, Tanno, L K, Simons, F E R, Sanchez-Borges, M, Cardona, V, Moon, H-B, Calderon, M A, Sisul, J C, Muraro, A, Casale, T et al. DOI: 10.1111/cea.12973
PMID: 26607825 Journal: ACTA DIABETOLOGICA Year: 2016 Reference: Acta Diabetol. 2016 Oct;53(5):857-8. doi: 10.1007/s00592-015-0818-9. Epub 2015 Nov 25. Impact factor: 3.074 Publication type: Letter or abstract Authors: Jose, Antonio San, Formiga, Francesc, Agusti, Antonia et al. DOI: 10.1007/s00592-015-0818-9
PMID: 27050764 Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Year: 2016 Reference: Clin Exp Rheumatol. 2016 Sep-Oct;34(6 Suppl 102):S41-S45. Epub 2016 Apr 1. Impact factor: 2.495 Publication type: Paper in international publication Authors: Garcia-Lozano, Jose-Raul, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Gonzalez-Leon, Rocio, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Julia, Maria Rosa, Solans, Roser, Blanco, Ricardo et al. DOI:
PMID: 25480887 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2016 Reference: Ann Rheum Dis. 2016 Feb;75(2):382-9. doi: 10.1136/annrheumdis-2014-206008. Epub 2014 Dec 5. Impact factor: 12.384 Publication type: Paper in international publication Authors: Praprotnik, Sonja, Sumida, Takayuki, Nishiyama, Sumusu, Caporali, Roberto, Kruize, Aike A, Vollenweider, Cristina, Ravaud, Philippe, Meiners, Petra, Brito-Zeron, Pilar, Vitali, Claudio et al. DOI: 10.1136/annrheumdis-2014-206008
PMID: 25433020 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2016 Reference: Ann Rheum Dis. 2016 Feb;75(2):348-55. doi: 10.1136/annrheumdis-2014-206418. Epub 2014 Nov 28. Impact factor: 9.27 Publication type: Paper in international publication Authors: Ramos-Casals, M, Retamozo, S, Gheitasi, H, Morera-Morales, M L, Brito-Zeron, P, Kostov, B, Solans, R, Fraile, G, Casanovas, A, Rascon, F J et al. DOI: 10.1136/annrheumdis-2014-206418
PMID: 25088654 Journal: MEDICINA CLINICA Year: 2015 Reference: Med Clin (Barc). 2015 May 8;144(9):430-1. doi: 10.1016/j.medcli.2014.06.002. Epub 2014 Aug 1. Impact factor: 1.417 Publication type: Letter or abstract Authors: Mestre-Torres, Jaume, Salcedo-Allende, M Teresa, Martinez-Valle, Ferran, Solans Laque, Roser et al. DOI: 10.1016/j.medcli.2014.06.002
PMID: 25187644 Journal: RHEUMATOLOGY Year: 2015 Reference: Rheumatology (Oxford). 2015 Mar;54(3):424-32. doi: 10.1093/rheumatology/keu336. Epub 2014 Sep 3. Impact factor: 4.475 Publication type: Paper in international publication Authors: Puechal, Xavier, De Luna, Gonzalo, Terrier, Benjamin, Kaminsky, Pierre, Le Quellec, Alain, Maurier, Francois, Solans, Roser, Godmer, Pascal, Costedoat-Chalumeau, Nathalie, Seror, Raphaele et al. DOI: 10.1093/rheumatology/keu336
PMID: 25641891 Journal: JOURNAL OF RHEUMATOLOGY Year: 2015 Reference: J Rheumatol. 2015 Apr;42(4):695-701. doi: 10.3899/jrheum.140949. Epub 2015 Feb 1. Impact factor: 3.187 Publication type: Paper in international publication Authors: Ortiz-Fernandez, Lourdes, Garcia-Lozano, Jose-Raul, Montes-Cano, Marco-Antonio, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Garcia-Hernandez, Francisco-Jose, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan, Blanco, Ricardo et al. DOI: 10.3899/jrheum.140949
PMID: 24442883 Journal: ANNALS OF THE RHEUMATIC DISEASES Year: 2015 Reference: Ann Rheum Dis. 2015 May;74(5):859-66. doi: 10.1136/annrheumdis-2013-204615. Epub 2014 Jan 17. Impact factor: 10.377 Publication type: Paper in international publication Authors: Sivils, Kathy L, Ng, Wan-Fai, Fauchais, Anne-Laure, Bombardieri, Stefano, Valesini, Guido, Bartoloni, Elena, Saraux, Alain, Tomsic, Matija, Sumida, Takayuki, Nishiyama, Susumu et al. DOI: 10.1136/annrheumdis-2013-204615
PMID: 24952504 Journal: NAT IMMUNOL Year: 2014 Reference: Nat Immunol. 2014 Aug;15(8):738-48. doi: 10.1038/ni.2919. Epub 2014 Jun 22. Impact factor: 24.973 Publication type: Paper in international publication Authors: Martin-Sanchez, Fatima, Gomez, Ana I, Martinez, Carlos M, Amores-Iniesta, Joaquin, Compan, Vincent, Barbera-Cremades, Maria, Yague, Jordi, Ruiz-Ortiz, Estibaliz, Anton, Jordi, Bujan, Segundo et al. DOI: 10.1038/ni.2919
PMID: 25019531 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Jul 14;9(7):e102100. doi: 10.1371/journal.pone.0102100. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Solans, Roser, Fanlo, Patricia, Carballeira, Monica Rodriguez, Camps, Teresa, Castaneda, Santos, Martin, Javier, Gonzalez-Escribano, Maria Francisca, Barnosi-Marin, Ana Celia, Gonzalez-Gay, Miguel Angel, Grana-Gil, Genaro et al. DOI: 10.1371/journal.pone.0102100
PMID: 25409453 Journal: PLOS ONE Year: 2014 Reference: PLoS One. 2014 Nov 19;9(11):e113476. doi: 10.1371/journal.pone.0113476. eCollection 2014. Impact factor: 3.534 Publication type: Paper in international publication Authors: Marquez, Ana, Solans, Roser, Hernandez-Rodriguez, Jose, Cid, Maria C, Castaneda, Santos, Ramentol, Marc, Rodriguez-Rodriguez, Luis, Narvaez, Javier, Blanco, Ricardo, Ortego-Centeno, Norberto et al. DOI: 10.1371/journal.pone.0113476
PMID: 24215577 Journal: ALLERGY Year: 2014 Reference: Allergy. 2014 Feb;69(2):159-67. doi: 10.1111/all.12314. Epub 2013 Nov 12. Impact factor: 5.995 Publication type: Review in national publication Authors: Akdis, C A, de Silva, D, Geromi, M, Panesar, S S, Muraro, A, Werfel, T, Hoffmann-Sommergruber, K, Roberts, G, Cardona, V, Dubois, A E J et al. DOI: 10.1111/all.12314
PMID: 23700188 Journal: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY Year: 2013 Reference: Eur J Clin Pharmacol. 2013 Sep;69(9):1689-99. doi: 10.1007/s00228-013-1518-4. Epub 2013 May 23. Impact factor: 2.741 Publication type: Paper in international publication Authors: Cortes-Hernandez, J, Danes, I, Agusti, A, Vallano, A, Martinez, J, Alerany, C, Ferrer, A, Lopez, A, Bosch, J A et al. DOI: 10.1007/s00228-013-1518-4
PMID: 23276619 Journal: MEDICINA CLINICA Year: 2013 Reference: Med Clin (Barc). 2013 Mar 2;140(5):214-6. doi: 10.1016/j.medcli.2012.10.009. Epub 2012 Dec 29. Impact factor: 1.399 Publication type: Editorial in national publication Authors: Ordi Ros, Josep, Consiglio, Francisco Javier et al. DOI: 10.1016/j.medcli.2012.10.009
PMID: 23122952 Journal: FERTILITY AND STERILITY Year: 2013 Reference: Fertil Steril. 2013 Feb;99(2):441-9. doi: 10.1016/j.fertnstert.2012.10.009. Epub 2012 Nov 2. Impact factor: 4.174 Publication type: Review in international publication Authors: Alijotas-Reig, Jaume, Palacio-Garcia, Carles, Llurba, Elisa, Vilardell-Tarres, Miquel et al. DOI: 10.1016/j.fertnstert.2012.10.009
PMID: 23515600 Journal: CLINICAL RHEUMATOLOGY Year: 2013 Reference: Clin Rheumatol. 2013 Jun;32(6):889-93. doi: 10.1007/s10067-013-2225-3. Epub 2013 Mar 21. Impact factor: 2.037 Publication type: Paper in international publication Authors: Martinez-Valle, Fernando, Castro-Marrero, Jesus, Detorres, Ines, Vilardell-Tarres, Miquel, Ordi-Ros, Jose, Fernandez-Codina, Andreu et al. DOI: 10.1007/s10067-013-2225-3
PMID: 22169458 Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM Year: 2012 Reference: Semin Arthritis Rheum. 2012 Jun;41(6):789-800. Epub 2011 Dec 12. Impact factor: 4.969 Publication type: Review in international publication Authors: , , , , , , , , , et al. DOI: 10.1016/j.semarthrit.2011.10.004
PMID: 22742541 Journal: TISSUE ANTIGENS Year: 2012 Reference: Tissue Antigens. 2012 Sep;80(3):254-8. doi: 10.1111/j.1399-0039.2012.01915.x. Epub 2012 Jun 29. Impact factor: 2.588 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1111/j.1399-0039.2012.01915.x
PMID: 22309435 Journal: ALLERGY Year: 2012 Reference: Allergy. 2012 Apr;67(4):462-76. doi: 10.1111/j.1398-9995.2012.02785.x. Epub 2012 Feb 6. Impact factor: 6.271 Publication type: Review in international publication Authors: Calderon, M, Cardona, V, Demoly, P et al. DOI: 10.1111/j.1398-9995.2012.02785.x
PMID: 22732951 Journal: MEDICINE Year: 2012 Reference: Medicine (Baltimore). 2012 Jul;91(4):206-11. Impact factor: 4.35 Publication type: Review in international publication Authors: , , , , , , , , et al. DOI: 10.1097/MD.0b013e318260977c
PMID: 21474199 Journal: IMMUNOBIOLOGY Year: 2011 Reference: Immunobiology. 2011 Sep;216(9):1034-7. Epub 2011 Mar 12. Impact factor: 4.114 Publication type: Paper in international publication Authors: , , , , , et al. DOI: 10.1016/j.imbio.2011.03.004
PMID: 21543090 Journal: MEDICINA CLINICA Year: 2011 Reference: Med Clin (Barc). 2011 Jun 11;137(2):77-83. Epub 2011 May 4. Impact factor: 1.413 Publication type: Editorial in national publication Authors: , , et al. DOI: 10.1016/j.medcli.2011.02.026
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PMID: 21509625 Journal: JOURNAL OF CLINICAL IMMUNOLOGY Year: 2011 Reference: J Clin Immunol. 2011 Aug;31(4):584-7. Epub 2011 Apr 21. Impact factor: 3.326 Publication type: Paper in international publication Authors: , , , , et al. DOI: 10.1007/s10875-011-9535-5
PMID: 20469961 Journal: JOURNAL OF WOMENS HEALTH Year: 2010 Reference: J Womens Health (Larchmt). 2010 Jun;19(6):1073-7. Impact factor: 1.77 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.1089/jwh.2008.1255
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PMID: 20415547 Journal: PHARMACOGENOMICS Year: 2010 Reference: Pharmacogenomics. 2010 May;11(5):617-9. Impact factor: 3.893 Publication type: Paper in international publication Authors: Marsal, Sara, Julia, Antonio et al. DOI: 10.2217/pgs.10.53
PMID: 20401492 Journal: HUMAN GENETICS Year: 2010 Reference: Hum Genet. 2010 Jul;128(1):27-37. doi: 10.1007/s00439-010-0817-4. Epub 2010 Apr 17. Impact factor: 4.042 Publication type: Paper in international publication Authors: , , et al. DOI: 10.1007/s00439-010-0817-4
PMID: 19578734 Journal: Adicciones Year: 2009 Reference: Adicciones. 2009;21(2):167-72. Impact factor: Publication type: Letter or abstract Authors: Rovira, Marc, Roncero, Carlos, Lopez-Ortiz, Cristina, Barral, Carmen, Saez-Francas, Naia, Casas, Miguel et al. DOI:
PMID: 19884273 Journal: JOURNAL OF RHEUMATOLOGY Year: 2009 Reference: J Rheumatol. 2009 Dec;36(12):2733-6. Impact factor: 3.282 Publication type: Paper in international publication Authors: , , , , , , , , , et al. DOI: 10.3899/jrheum.090377
PMID: 19889318 Journal: REVISTA CLINICA ESPANOLA Year: 2009 Reference: Rev Clin Esp. 2009 Nov;209(10):483-4. Impact factor: 0.734 Publication type: Review or editorial in national publication Authors: Vilardell Tarres, M et al. DOI:
PMID: 19736998 Journal: JOURNAL OF PROTEOME RESEARCH Year: 2009 Reference: J Proteome Res. 2009 Oct;8(10):4799-809. Impact factor: 5.684 Publication type: Paper in international publication Authors: Rezzi, Serge, Martin, Francois-Pierre, Alonso, Carmen, Guilarte, Mar, Vicario, Maria, Ramos, Laura, Martinez, Cristina, Lobo, Beatriz, Saperas, Esteban, Malagelada, Juan Ramon et al. DOI: 10.1021/pr900525w
Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.
It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.
The study showing how thrombocytopenia increases the risk of thrombosis in patients with antiphospholipid syndrome has been considered the best paper published in 2021.