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Systemic Diseases

The Systemic Diseases group performs translational research based on at least 300 patients with systemic lupus erytomatosus (SLE), antiphospholipid syndrome (APS), systemic sclerosis, vasculitis, dermatomyitis, Sjörgen syndrome or autoinflammatory syndromes in order to better understand their pathogenesis (both at the immunological and genetic regulation level), study their clinical and biological expression (through the detection of new markers that help characterize each of the autoimmune diseases), study morbimortality (through epidemiological studies) and analyse patients' response to medications. With these goals in mind, we seek to improve the diagnosis, clinical monitoring, and prognosis of our patients.

Research lines

Spanish Registry of patients with Systemic vasculitides (REVAS).

This is a multicentre study supported by the Systemic Autoimmune Diseases Group (GEAS) from the Spanish Internal Medicine Society (SEMI). The aim of the study is to describe the different clinical forms of presentation of these diseases, the response to the conventional treatment of the different subtypes of vasculitides, and the prognostic factors and survival in our country. This study includes 17 Hospitals from Spain with a cohort of 300 patients. We are the study coordinator Centre.

IP: Roser Solans Laque

Spanish Registry of Scleroderma patients (Systemic Autoimmune Diseases Group, Spanish Internal Medicine Association).

This multicentric study includes 14 hospitals with a cohort of 916 scleroderma patients. Its main goal consists in determining both the prognosis factors and the survival of these patients.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Specific Antinuclear antibodies of scleroderma as markers for different clinical patterns.

We want to establish the relationship between the presence of specific autoantibodies for scleroderma (anti-centromere, anti-topoisomerase 1, anti-polymerase III, anti-U3 RNP, Anti-Th/To, Anti-Pm/Scl, anti-Ku) with the different demographic and clinical features as well as with the disease prognosis.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Study of IFN-gamma/STAT and TGF-beta/SMAD pathways in lupus patients with skin involvement. Role in the evolution to fibrosis.

With this project we aim at studying the status of the IFN-gamma/STAT and the TGF-beta/Smad intracellular signal pathways in cutaneous biopsies of patients with lupus. We are now analyzing the expression of several molecules involved in these pathways to be able both to discern the main differences among the different types of cutaneous lupus and to interpret the residual fibrotic lesions observed in discoid lupus.

IP: José Ordi Ros

Publications

First Description of Late-Onset Autoinflammatory Disease Due to Somatic NLRC4 Mosaicism.

PMID: 34672126
Journal: Arthritis & Rheumatology
Year: 2022
Reference: Arthritis Rheumatol. 2022 Apr;74(4):692-699. doi: 10.1002/art.41999. Epub 2022 Feb 14.
Impact factor: 10.995
Publication type: Paper in international publication
Authors: Ionescu, Daniela, Penin-Franch, Alejandro, Mensa-Vilaro, Anna, Castillo, Paola, Hurtado-Navarro, Laura, Molina-Lopez, Cristina, Romero-Chala, Silvia, Plaza, Susana, Fabregat, Virginia, Bujan, Segundo et al.
DOI: 10.1002/art.41999

Reliability assessment of the definition of ultrasound enthesitis in SpA: results of a large, multicentre, international web-based study.

PMID: 35293988
Journal: RHEUMATOLOGY
Year: 2022
Reference: Rheumatology (Oxford). 2022 Mar 16. pii: 6549521. doi: 10.1093/rheumatology/keac162.
Impact factor: 7.58
Publication type: Paper in international publication
Authors: Di Matteo, Andrea, Cipolletta, Edoardo, Destro Castaniti, Giulia Maria, Smerilli, Gianluca, Airoldi, Carla, Aydin, Sibel Zehra, Becciolini, Andrea, Bonfiglioli, Karina, Bruns, Alessandra, Carrara, Greta et al.
DOI: 10.1093/rheumatology/keac162

Cancer screening in idiopathic inflammatory myopathies: Ten years experience from a single center.

PMID: 35051890
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2022
Reference: Semin Arthritis Rheum. 2022 Apr;53:151940. doi: 10.1016/j.semarthrit.2021.12.008. Epub 2021 Dec 31.
Impact factor: 5.532
Publication type: Paper in international publication
Authors: Trallero-Araguas, Ernesto, Gil-Vila, Albert, Martinez-Gomez, X, Pinal-Fernandez, Iago, Alvarado-Cardenas, M, Simo-Perdigo, M, Selva-O'Callaghan, Albert et al.
DOI: 10.1016/j.semarthrit.2021.12.008

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.

PMID: 34099189
Journal: BIOLOGICAL PSYCHIATRY
Year: 2022
Reference: Biol Psychiatry. 2022 Jan 1;91(1):102-117. doi: 10.1016/j.biopsych.2021.02.972. Epub 2021 Mar 23.
Impact factor: 13.382
Publication type: Paper in international publication
Authors: Ophoff, Roel A, Jonsson, Erik G, Palotie, Aarno, Ehrenreich, Hannelore, Begemann, Martin, Steixner-Kumar, Agnes, Sham, Pak C, Iwata, Nakao, Weinberger, Daniel R, Gejman, Pablo V et al.
DOI: 10.1016/j.biopsych.2021.02.972

Myositis and myasteniform syndrome related to pembrolizumab.

PMID: 34290006
Journal: BMJ case reports
Year: 2021
Reference: BMJ Case Rep. 2021 Jul 21;14(7). pii: 14/7/e241766. doi: 10.1136/bcr-2021-241766.
Impact factor: 0
Publication type: Letter or abstract
Authors: Montoro, Bruno, Sanchez-Sancho, Pablo, Selva-O'Callaghan, Albert, Trallero-Araguas, Ernesto, Ros, Javier et al.
DOI: 10.1136/bcr-2021-241766

SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.

PMID: 34262032
Journal: Nature Communications
Year: 2021
Reference: Nat Commun. 2021 Jul 14;12(1):4319. doi: 10.1038/s41467-021-24618-3.
Impact factor: 14.919
Publication type: Paper in international publication
Authors: Andrades, Alvaro, Trastulli, Deborah, Pros, Eva, Setien, Fernando, Verdura, Sara, Farre, Lourdes, Martin-Tejera, Juan F, Llabata, Paula, Oaknin, Ana, Saigi, Maria et al.
DOI: 10.1038/s41467-021-24618-3

Anaphylaxis viewed by experts: unmet needs.

PMID: 34269744
Journal: Current opinion in allergy and clinical immunology
Year: 2021
Reference: Curr Opin Allergy Clin Immunol. 2021 Oct 1;21(5):435-441. doi: 10.1097/ACI.0000000000000771.
Impact factor: 0
Publication type: Review in international publication
Authors: Sala-Cunill, Anna, Cardona, Victoria et al.
DOI: 10.1097/ACI.0000000000000771

Erratum to "IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper" [World Allergy Organ J 13/2 (2020) 100080].

PMID: 34221218
Journal: World Allergy Organization Journal
Year: 2021
Reference: World Allergy Organ J. 2021 Jun 17;14(7):100557. doi: 10.1016/j.waojou.2021.100557. eCollection 2021 Jul.
Impact factor: 4.084
Publication type: Letter or abstract
Authors: Canonica, Giorgio Walter, Ansotegui, Ignacio J, Melioli, Giovanni, Monge Ortega, Olga Patricia, Morais-Almeida, Mario, Pfaar, Oliver, Poulsen, Lars K, Pawankar, Ruby, Renz, Harald E, Romano, Antonino G et al.
DOI: 10.1016/j.waojou.2021.100557

Statin use and myopathy. Not always guilty.

PMID: 32500148
Journal: RHEUMATOLOGY
Year: 2020
Reference: Rheumatology (Oxford). 2020 Dec 1;59(12):3853-3857. doi: 10.1093/rheumatology/keaa180.
Impact factor: 5.606
Publication type: Paper in international publication
Authors: Moreno, Pedro J, Milisenda, Jose C, Selva O'Callaghan, Albert, Grau, Josep M, Padrosa, Joan, Antoniol, Maria N et al.
DOI: 10.1093/rheumatology/keaa180

Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology.

PMID: 32455633
Journal: Journal of Clinical Medicine
Year: 2020
Reference: J Clin Med. 2020 May 21;9(5). pii: jcm9051557. doi: 10.3390/jcm9051557.
Impact factor: 3.303
Publication type: Review in international publication
Authors: Wang-Steverding, Xia, Bakken, Inger Johanne, Ivanovs, Andrejs, Castro-Marrero, Jesus, Nacul, Luis, Alegre, Jose, Zalewski, Pawel, Slomko, Joanna, Strand, Elin Bolle, Pheby, Derek et al.
DOI: 10.3390/jcm9051557

A questionnaire-based study on contraceptive practice in patients with rheumatic disease found no significant difference in age-matched healthy controls.

PMID: 32424615
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2020
Reference: Rheumatol Int. 2020 Sep;40(9):1473-1480. doi: 10.1007/s00296-020-04598-1. Epub 2020 May 18.
Impact factor: 1.984
Publication type: Paper in international publication
Authors: Marsal, Sara, Forger, Frauke, Ostensen, Monika, Julia, Antonio, Micu, Mihaela C, Pluma, Andrea et al.
DOI: 10.1007/s00296-020-04598-1

Incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases treated with targeted biologic and synthetic disease-modifying anti-rheumatic drugs.

PMID: 32425260
Journal: SEMINARS IN ARTHRITIS AND RHEUMATISM
Year: 2020
Reference: Semin Arthritis Rheum. 2020 May 16. doi: 10.1016/j.semarthrit.2020.05.001.
Impact factor: 4.751
Publication type: Paper in international publication
Authors: Moreno, Estefanía, Michelena, Xabier, Borrell, Helena, López-Corbeto, Mireia, López-Lasanta, María, Serrat, Mayte, Espartal, Esther, Antón, Susana, Añez, Gustavo Adolfo, Caparrós-Ruiz, Raquel et al.
DOI: 10.1016/j.semarthrit.2020.05.001

[Clinical Practice Guide for Anaphylaxis in Latin America (Galaxia-Latam)].

PMID: 31443138
Journal: Revista Alergia Mexico
Year: 2019
Reference: Rev Alerg Mex. 2019;66 Suppl 2:1-39. doi: 10.29262/ram.v66i6.588.
Impact factor: 0
Publication type: Paper in international publication
Authors: Fernandez-Rivas, Montserrat, Gangoiti, Iker, Guardia-Martinez, Pedro, Herranz-Sanz, Miguel Angel, Julia-Benito, Juan Carlos, Lobera-Labairu, Teofilo, Praena-Crespo, Manuel, Prieto-Romo, Jose Ignacio, Sanchez-Salguero, Carlos, Sanchez-Gonzalez, Jose Ignacio et al.
DOI: 10.29262/ram.v66i6.588

Mobile technology in allergic rhinitis: evolution in management or revolution in health and care?

PMID: 31445223
Journal: Journal of Allergy and Clinical Immunology-In Practice
Year: 2019
Reference: J Allergy Clin Immunol Pract. 2019 Nov - Dec;7(8):2511-2523. doi: 10.1016/j.jaip.2019.07.044. Epub 2019 Aug 21.
Impact factor: 7.55
Publication type: Paper in international publication
Authors: Bousquet, Jean, Ansotegui, Ignacio J, Anto, Josep M, Arnavielhe, Sylvie, Bachert, Claus, Basagana, Xavier, Bedard, Annabelle, Bedbrook, Anna, Bonini, Matteo, Bosnic-Anticevich, Sinthia et al.
DOI: 10.1016/j.jaip.2019.07.044

Identification of distinctive interferon gene signatures in different types of myositis.

PMID: 31434690
Journal: NEUROLOGY
Year: 2019
Reference: Neurology. 2019 Sep 17;93(12):e1193-e1204. doi: 10.1212/WNL.0000000000008128. Epub 2019 Aug 21.
Impact factor: 8.689
Publication type: Paper in international publication
Authors: Paik, Julie, Albayda, Jemima, Christopher-Stine, Lisa, Lloyd, Thomas E, Corse, Andrea M, Mammen, Andrew L, Selva-O'Callaghan, Albert, Grau-Junyent, Josep M, Milisenda, Jose C, Miller, Frederick W et al.
DOI: 10.1212/WNL.0000000000008128

Characteristics, quality of life and control of respiratory allergic diseases caused by house dust mites (HDMs) in Spain: a cross-sectional study.

PMID: 31406567
Journal: Clinical and Translational Allergy
Year: 2019
Reference: Clin Transl Allergy. 2019 Aug 6;9:39. doi: 10.1186/s13601-019-0276-5. eCollection 2019.
Impact factor: 4.232
Publication type: Paper in international publication
Authors: Ana, Beristain, Montoro, Javier, Moreno, Carmen, Moya, Carmen, Pamies, Rafael, Perez-Pastor, Laura, Quinones, Dolores, Raducan, Isabella, Rodriguez, Fernando, Rodriguez-Pacheco, Ramon et al.
DOI: 10.1186/s13601-019-0276-5

The Jarisch-Herxheimer reaction in syphilis: could molecular typing help to understand it better?

PMID: 29775498
Journal: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
Year: 2018
Reference: J Eur Acad Dermatol Venereol. 2018 Oct;32(10):1791-1795. doi: 10.1111/jdv.15078. Epub 2018 Jun 8.
Impact factor: 4.287
Publication type: Paper in international publication
Authors: Alvarez, A, Armegol, P, Barbera, M J, Esperalba, J, Vall-Mayans, M, Mota-Foix, M, Fernandez, C, Arando, M et al.
DOI: 10.1111/jdv.15078

Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.

PMID: 29768139
Journal: NEW ENGLAND JOURNAL OF MEDICINE
Year: 2018
Reference: N Engl J Med. 2018 May 17;378(20):1908-1919. doi: 10.1056/NEJMoa1706314.
Impact factor: 79.258
Publication type: Paper in international publication
Authors: Livneh, Avi, Brogan, Paul, Cattalini, Marco, Obici, Laura, Lheritier, Karine, Speziale, Antonio, Junge, Guido, Gul, Ahmet, Constantin, Tamas, Bujan-Rivas, Segundo et al.
DOI: 10.1056/NEJMoa1706314

Poor self-reported sleep quality and health-related quality of life in patients with chronic fatigue syndrome/myalgic encephalomyelitis.

PMID: 29770505
Journal: JOURNAL OF SLEEP RESEARCH
Year: 2018
Reference: J Sleep Res. 2018 Dec;27(6):e12703. doi: 10.1111/jsr.12703. Epub 2018 May 16.
Impact factor: 3.433
Publication type: Paper in international publication
Authors: Castro-Marrero, Jesus, Zaragoza, Maria C, Gonzalez-Garcia, Sergio, Aliste, Luisa, Saez-Francas, Naia, Romero, Odile, Fernandez de Sevilla, Tomas, Alegre, Jose, Ferre, Alex et al.
DOI: 10.1111/jsr.12703

Venous thrombosis and relapses in patients with Behcet's disease. Descriptive analysis from Spanish network of Behcet's disease (REGEB cohort).

PMID: 29745871
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Year: 2018
Reference: Clin Exp Rheumatol. 2018 Nov-Dec;36 Suppl 115(6):40-44. Epub 2018 May 3.
Impact factor: 3.201
Publication type: Paper in international publication
Authors: Nieto, Javier, Solanich, Xavier, Martinez-Valle, Ferran, Fonseca, Eva, Munoz, Francisco Jose, Fraile, Guadalupe, de Escalante, Begona, Boldova, Rafael, Hurtado, Robert, Espinosa, Gerard et al.
DOI:

RIG-I expression in perifascicular myofibers is a reliable biomarker of dermatomyositis.

PMID: 28738907
Journal: ARTHRITIS RESEARCH & THERAPY
Year: 2017
Reference: Arthritis Res Ther. 2017 Jul 24;19(1):174. doi: 10.1186/s13075-017-1383-0.
Impact factor: 4.121
Publication type: Paper in international publication
Authors: Suarez-Calvet, Xavier, Gallardo, Eduard, Pinal-Fernandez, Iago, De Luna, Noemi, Lleixa, Cinta, Diaz-Manera, Jordi, Rojas-Garcia, Ricardo, Castellvi, Ivan, Martinez, M Angeles, Grau, Josep M et al.
DOI: 10.1186/s13075-017-1383-0

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts.

PMID: 28658137
Journal: MEDICINE
Year: 2017
Reference: Medicine (Baltimore). 2017 Jun;96(26):e7308. doi: 10.1097/MD.0000000000007308.
Impact factor: 1.803
Publication type: Paper in international publication
Authors: Blanco, Francisco, Fernandez-Gutierrez, Benjamin, Perrotti, Pedro P, Gisbert, Javier P, Domenech, Eugeni, Fernandez-Nebro, Antonio, Canete, Juan D, Ferrandiz, Carlos, Tornero, Jesus, Garcia-Sanchez, Valle et al.
DOI: 10.1097/MD.0000000000007308

[Management of anaphylaxis in Latin America: current situation].

PMID: 28658725
Journal: Revista alergia Mexico (Tecamachalco, Puebla, Mexi
Year: 2017
Reference: Rev Alerg Mex. 2017 Apr-Jun;64(2):171-177.
Impact factor: 0
Publication type: Paper in national publication
Authors: Cardona, Victoria, Alvarez-Perea, Alberto, Ansotegui, Ignacio J, Arias-Cruz, Alfredo, Gonzalez-Diaz, Sandra Nora, Latour-Staffeld, Patricia, Ivancevich, Juan Carlos, Sanchez-Borges, Mario, Serrano, Carlos, Sole, Dirceu et al.
DOI:

An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis.

PMID: 28668810
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2017
Reference: J Rheumatol. 2017 Oct;44(10):1453-1457. doi: 10.3899/jrheum.161369. Epub 2017 Jul 1.
Impact factor: 3.15
Publication type: Paper in international publication
Authors: Garcia-Hernandez, Francisco J, Madronero, Ana Belen, Beretta, Lorenzo, Santaniello, Alessandro, Lunardi, Claudio, Airo, Paolo, Hoffmann-Vold, Anna-Maria, Kreuter, Alexander, Riemekasten, Gabriela, Witte, Torsten et al.
DOI: 10.3899/jrheum.161369

Borderline Personality Disorder and Personality Inventory for DSM-5 (PID-5): Dimensional personality assessment with DSM-5.

PMID: 27624429
Journal: COMPREHENSIVE PSYCHIATRY
Year: 2016
Reference: Compr Psychiatry. 2016 Oct;70:105-11. doi: 10.1016/j.comppsych.2016.07.002. Epub 2016 Jul 5.
Impact factor: 2.043
Publication type: Paper in international publication
Authors: Calvo, Natalia, Valero, Sergi, Saez-Francas, Naia, Gutierrez, Fernando, Casas, Miguel, Ferrer, Marc et al.
DOI: 10.1016/j.comppsych.2016.07.002

Urine metabolome profiling of immune-mediated inflammatory diseases.

PMID: 27609333
Journal: BMC Medicine
Year: 2016
Reference: BMC Med. 2016 Sep 8;14(1):133. doi: 10.1186/s12916-016-0681-8.
Impact factor: 8.005
Publication type: Paper in international publication
Authors: Casbas, Ana Gutierrez, Alonso, Arnald, Julia, Antonio, Vinaixa, Maria, Domenech, Eugeni, Fernandez-Nebro, Antonio, Canete, Juan D, Ferrandiz, Carlos, Tornero, Jesus, Gisbert, Javier P et al.
DOI: 10.1186/s12916-016-0681-8

Genetic Analysis with the Immunochip Platform in Behcet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.

PMID: 27548383
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Aug 22;11(8):e0161305. doi: 10.1371/journal.pone.0161305. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Ortiz-Fernandez, Lourdes, Carmona, Francisco-David, Montes-Cano, Marco-Antonio, Garcia-Lozano, Jose-Raul, Conde-Jaldon, Marta, Ortego-Centeno, Norberto, Castillo, Maria Jesus, Espinosa, Gerard, Grana-Gil, Genaro, Sanchez-Burson, Juan et al.
DOI: 10.1371/journal.pone.0161305

Zika virus infection in pregnant women in Barcelona, Spain.

PMID: 27063354
Journal: CLINICAL MICROBIOLOGY AND INFECTION
Year: 2016
Reference: Clin Microbiol Infect. 2016 Jul;22(7):648-50. doi: 10.1016/j.cmi.2016.03.025. Epub 2016 Apr 6.
Impact factor: 4.575
Publication type: Paper in international publication
Authors: Bocanegra, C, Sulleiro, E, Soriano-Arandes, A, Pou, D, Suy, A, Llurba, E, Rodo, C, Espasa, M, Campins, M, Martin, A et al.
DOI: 10.1016/j.cmi.2016.03.025

Analytical methods in untargeted metabolomics: state of the art in 2015.

PMID: 25798438
Journal: Annals of Animal Science
Year: 2015
Reference: Front Bioeng Biotechnol. 2015 Mar 5;3:23. doi: 10.3389/fbioe.2015.00023. eCollection 2015.
Impact factor: 0.613
Publication type: Review in national publication
Authors: Alonso, Arnald, Marsal, Sara, Julia, Antonio et al.
DOI: 10.3389/fbioe.2015.00023

2014 update of the Consensus Statement of the Spanish Society of Rheumatology on the use of biological therapies in rheumatoid arthritis.

PMID: 26051464
Journal: Reumatologia clinica
Year: 2015
Reference: Reumatol Clin. 2015 Sep-Oct;11(5):279-294. doi: 10.1016/j.reuma.2015.05.001. Epub 2015 Jun 6.
Impact factor: 0
Publication type: Paper in international publication
Authors: Sanmarti, Raimon, Garcia-Rodriguez, Susana, Alvaro-Gracia, Jose Maria, Andreu, Jose Luis, Balsa, Alejandro, Caliz, Rafael, Fernandez-Nebro, Antonio, Ferraz-Amaro, Ivan, Gomez-Reino, Juan Jesus, Gonzalez-Alvaro, Isidoro et al.
DOI: 10.1016/j.reuma.2015.05.001

A deletion at ADAMTS9-MAGI1 locus is associated with psoriatic arthritis risk.

PMID: 25990289
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2015
Reference: Ann Rheum Dis. 2015 Oct;74(10):1875-81. doi: 10.1136/annrheumdis-2014-207190. Epub 2015 May 19.
Impact factor: 10.377
Publication type: Paper in international publication
Authors: Canete, Juan D, Rubio, Esteban, Salvador, Georgina, Diaz-Torne, Cesar, Blanco, Ricardo, Willisch Dominguez, Alfredo, Mosquera, Jose Antonio, Vela, Paloma, Tornero, Jesus, Sanchez-Fernandez, Simon et al.
DOI: 10.1136/annrheumdis-2014-207190

Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis.

PMID: 25848939
Journal: PLoS One
Year: 2015
Reference: PLoS One. 2015 Apr 7;10(4):e0122088. doi: 10.1371/journal.pone.0122088. eCollection 2015.
Impact factor: 3.234
Publication type: Paper in international publication
Authors: Tornero, Jesus, Fernandez-Nebro, Antonio, Blanco, Francisco, Gonzalez-Alvaro, Isidoro, Canete, Juan D, Maymo, Joan, Alperiz, Mercedes, Fernandez-Gutierrez, Benjamin, Olive, Alex, Corominas, Hector et al.
DOI: 10.1371/journal.pone.0122088

EAACI food allergy and anaphylaxis guidelines: diagnosis and management of food allergy.

PMID: 24909706
Journal: ALLERGY
Year: 2014
Reference: Allergy. 2014 Aug;69(8):1008-25. doi: 10.1111/all.12429. Epub 2014 Jun 9.
Impact factor: 5.995
Publication type: Clinical guide
Authors: Worm, M, Vlieg-Boerstra, B, Panesar, S, de Silva, D, Soares-Weiser, K, Sheikh, A, Ballmer-Weber, B K, Nilsson, C, de Jong, N W, Akdis, C A et al.
DOI: 10.1111/all.12429

Primary prevention of food allergy in children and adults: systematic review.

PMID: 24433563
Journal: ALLERGY
Year: 2014
Reference: Allergy. 2014 May;69(5):581-9. doi: 10.1111/all.12334. Epub 2014 Jan 16.
Impact factor: 5.995
Publication type: Review in international publication
Authors: Poulsen, L K, de Silva, D, Geromi, M, Halken, S, Host, A, Panesar, S S, Muraro, A, Werfel, T, Hoffmann-Sommergruber, K, Roberts, G et al.
DOI: 10.1111/all.12334

Management of angioedema without urticaria in the emergency department.

PMID: 25580506
Journal: ANN MED
Year: 2014
Reference: Ann Med. 2014 Dec;46(8):607-18. doi: 10.3109/07853890.2014.949300.
Impact factor: 4.733
Publication type: Review in international publication
Authors: Cabanas, R, Campos, A, Cimbollek, S, Gomez-Traseira, C, Quevedo, T Gonzalez, Guilarte, M, Jurado-Palomo, J, Lobera, T, Lopez-Serrano, M C, Marcos, C et al.
DOI:

Component resolved diagnosis: when should it be used?

PMID: 25250172
Journal: Clinical and Translational Allergy
Year: 2014
Reference: Clin Transl Allergy. 2014 Sep 8;4:28. doi: 10.1186/2045-7022-4-28. eCollection 2014.
Impact factor: 0
Publication type: Letter or abstract
Authors: Luengo, Olga, Cardona, Victoria et al.
DOI: 10.1186/2045-7022-4-28

New insight on the Xq28 association with systemic sclerosis.

PMID: 23444193
Journal: ANNALS OF THE RHEUMATIC DISEASES
Year: 2013
Reference: Ann Rheum Dis. 2013 Dec 1;72(12):2032-8. doi: 10.1136/annrheumdis-2012-202742. Epub 2013 Feb 26.
Impact factor: 9.111
Publication type: Paper in international publication
Authors: Arnett, Frank C, Tan, Filemon K, Assassi, Shervin, Radstake, Timothy R D J, Mayes, Maureen D, Martin, Javier, Worthington, Jane, Herrick, Ariane, Denton, Christopher P, Fonseca, Carmen et al.
DOI: 10.1136/annrheumdis-2012-202742

Soluble CD40 ligand in morbidly obese patients: effect of body mass index on recovery to normal levels after gastric bypass surgery.

PMID: 23426590
Journal: ARCHIVES OF SURGERY
Year: 2013
Reference: JAMA Surg. 2013 Feb;148(2):151-6. doi: 10.1001/jamasurgery.2013.419.
Impact factor: 4.1
Publication type: Paper in international publication
Authors: Peinado-Onsurbe, Julia, Vargas, Victor, Baena-Fustegueras, Juan A, Pardina, Eva, Balada, Eva, Ferrer, Roser, Catalan, Roberto, Rivero, Joaquin, Casals, Isidre, Lecube, Albert et al.
DOI: 10.1001/jamasurgery.2013.419

Social costs of icatibant self-administration vs. health professional-administration in the treatment of hereditary angioedema in Spain.

PMID: 23398817
Journal: Health economics review
Year: 2013
Reference: Health Econ Rev. 2013 Feb 12;3(1):2. doi: 10.1186/2191-1991-3-2.
Impact factor:
Publication type: Letter or abstract
Authors: Blasco, Antonio J, Lazaro, Pablo, Caballero, Teresa, Guilarte, Mar et al.
DOI: 10.1186/2191-1991-3-2

Validation of the first treatment-specific questionnaire for the assessment of patient satisfaction with allergen-specific immunotherapy in allergic patients: The ESPIA questionnaire.

PMID: 23352631
Journal: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Year: 2013
Reference: J Allergy Clin Immunol. 2013 Jun;131(6):1539-46. doi: 10.1016/j.jaci.2012.11.049. Epub 2013 Jan 23.
Impact factor: 12.047
Publication type: Paper in international publication
Authors: Justicia, Jose Luis, Cardona, Victoria, Guardia, Pedro, Ojeda, Pedro, Olaguibel, Jose Maria, Vega, Jose Maria, Vidal, Carmen, Baro, Eva, Garcia, Mario Alberto et al.
DOI: 10.1016/j.jaci.2012.11.049

[Update in hereditary angioedema due to C1 inhibitor deficiency.]

PMID: 22677048
Journal: MEDICINA CLINICA
Year: 2012
Reference: Med Clin (Barc). 2012 Oct 20;139(10):452-7. doi: 10.1016/j.medcli.2012.03.024. Epub 2012 Jun 5.
Impact factor: 1.385
Publication type: Editorial in national publication
Authors: et al.
DOI: 10.1016/j.medcli.2012.03.024

The autoimmune disease-associated IL2RA locus is involved in the clinical manifestations of systemic sclerosis.

PMID: 22012429
Journal: GENES AND IMMUNITY
Year: 2012
Reference: Genes Immun. 2012 Feb;13(2):191-6. doi: 10.1038/gene.2011.72. Epub 2011 Oct 20.
Impact factor: 3.872
Publication type: Paper in international publication
Authors: Carmona, F D, Broen, J C A, Simeon, C P, Vonk, M C, Carreira, P, Rios-Fernandez, R, Espinosa, G, Vicente-Rabaneda, E, Tolosa, C, Garcia-Hernandez, F J et al.
DOI: 10.1038/gene.2011.72

Attention-deficit hyperactivity disorder in chronic fatigue syndrome patients.

PMID: 22648008
Journal: PSYCHIATRY RESEARCH
Year: 2012
Reference: Psychiatry Res. 2012 Dec 30;200(2-3):748-53. doi: 10.1016/j.psychres.2012.04.041. Epub 2012 May 28.
Impact factor: 2.524
Publication type: Paper in international publication
Authors: , , , , , , et al.
DOI: 10.1016/j.psychres.2012.04.041

Acute experimental stress evokes a differential gender-determined increase in human intestinal macromolecular permeability.

PMID: 22625665
Journal: NEUROGASTROENTEROLOGY AND MOTILITY
Year: 2012
Reference: Neurogastroenterol Motil. 2012 Aug;24(8):740-6, e348-9. doi: 10.1111/j.1365-2982.2012.01928.x. Epub 2012 May 24.
Impact factor: 3.414
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1111/j.1365-2982.2012.01928.x

Systemic lupus erythematosus as a first presentation of common variable immunodeficiency associated with infrequent mannose-binding lectin gene polymorphisms.

PMID: 19851769
Journal: RHEUMATOLOGY INTERNATIONAL
Year: 2011
Reference: Rheumatol Int. 2011 Apr;31(4):537-41. Epub 2009 Oct 23.
Impact factor: 1.431
Publication type: Paper in international publication
Authors: , , , , et al.
DOI: 10.1007/s00296-009-1209-8

SPECT imaging for brain improvement quantification in a patient with cerebrotendinous xanthomatosis.

PMID: 21157207
Journal: CLINICAL NUCLEAR MEDICINE
Year: 2011
Reference: Clin Nucl Med. 2011 Jan;36(1):38-9.
Impact factor: 3.766
Publication type: Editorail in international publication
Authors: Selva-O'Callaghan, Albert, Bardes, Ignasi, Jacas, Carlos, Jubany, Lluis, Lorenzo-Bosquet, Carles, Cuberas-Borros, Gemma, Vilardell-Tarres, Miquel et al.
DOI: 10.1097/RLU.0b013e3181feed83

[The role of depression in cognitive inpairment in patients with chronic fatigue syndrome.]

PMID: 21145567
Journal: MEDICINA CLINICA
Year: 2011
Reference: Med Clin (Barc). 2011 Mar 12;136(6):239-243. Epub 2010 Dec 9.
Impact factor: 1.413
Publication type: Paper in national publication
Authors: , , , , , , et al.
DOI: 10.1016/j.medcli.2010.07.022

AStream: An R package for annotating LC/MS metabolomic data.

PMID: 21414990
Journal: BIOINFORMATICS
Year: 2011
Reference: Bioinformatics. 2011 May 1;27(9):1339-40. Epub 2011 Mar 16.
Impact factor: 4.877
Publication type: Paper in international publication
Authors: , , , , , , , et al.
DOI: 10.1093/bioinformatics/btr138

Age-related survival and clinical features in systemic sclerosis patients older or younger than 65 at diagnosis.

PMID: 20223816
Journal: RHEUMATOLOGY
Year: 2010
Reference: Rheumatology (Oxford). 2010 Jun;49(6):1112-7. doi: 10.1093/rheumatology/keq046. Epub 2010 Mar 11.
Impact factor: 4.236
Publication type: Paper in international publication
Authors: , , , , , et al.
DOI: 10.1093/rheumatology/keq046

Preliminary cross-cultural adaptation of a new pediatric health-related quality of life scale in children with systemic lupus erythematosus: an international effort.

PMID: 19934176
Journal: LUPUS
Year: 2010
Reference: Lupus. 2010 Jan;19(1):83-8. Epub 2009 Nov 24.
Impact factor: 2.586
Publication type: Paper in international publication
Authors: Ravelli, A, Almeida de Jesus, A, Campos, L M, Carvalho, J, Hilario, M O, Knupp Feitosa de Oliveira, S, Len, C A, Oliveira Sato, J, Saad-Magalhaes, C, Silva, C A et al.
DOI: 10.1177/0961203309345770

Deletion of the late cornified envelope genes, LCE3C and LCE3B, is associated with rheumatoid arthritis.

PMID: 20213803
Journal: ARTHRITIS AND RHEUMATISM
Year: 2010
Reference: Arthritis Rheum. 2010 May;62(5):1246-51.
Impact factor: 7.332
Publication type: Paper in international publication
Authors: , , , , , , , , , et al.
DOI: 10.1002/art.27381

[Home intravenous antibiotic therapy of hepatic abscess: Safety, efficacy and predictive factor of hospital readmission.]

PMID: 20202654
Journal: MEDICINA CLINICA
Year: 2010
Reference: Med Clin (Barc). 2010 Apr 17;134(11):473-6. Epub 2010 Mar 4.
Impact factor: 1.231
Publication type: Paper in national publication
Authors: , , , et al.
DOI: 10.1016/j.medcli.2009.10.050

An eight-gene blood expression profile predicts the response to infliximab in rheumatoid arthritis.

PMID: 19847310
Journal: PLoS One
Year: 2009
Reference: PLoS One. 2009 Oct 22;4(10):e7556.
Impact factor:
Publication type: Letter or abstract
Authors: Barcelo, Pere, Julia, Antonio, Erra, Alba, Palacio, Carles, Tomas, Carlos, Sans, Xavier, Marsal, Sara et al.
DOI: 10.1371/journal.pone.0007556

Identification of candidate genes for rituximab response in rheumatoid arthritis patients by microarray expression profiling in blood cells.

PMID: 19842941
Journal: PHARMACOGENOMICS
Year: 2009
Reference: Pharmacogenomics. 2009 Oct;10(10):1697-708.
Impact factor: 3.551
Publication type: Paper in international publication
Authors: Julia, Antonio, Barcelo, Mireia, Erra, Alba, Palacio, Carles, Marsal, Sara et al.
DOI: 10.2217/pgs.09.99

Changes in lipid profile between flare and remission of patients with systemic lupus erythematosus: a prospective study.

PMID: 19531751
Journal: JOURNAL OF RHEUMATOLOGY
Year: 2009
Reference: J Rheumatol. 2009 Aug;36(8):1639-45.
Impact factor: 3.282
Publication type: Paper in international publication
Authors: Urquizu-Padilla, Maria, Balada, Eva, Chacon, Pilar, Perez, Eduardo Hermosilla, Vilardell-Tarres, Miquel, Ordi-Ros, Josep et al.
DOI: 10.3899/jrheum.081097

Genetic risk factors of thrombosis in the antiphospholipid syndrome.

PMID: 19659549
Journal: BRITISH JOURNAL OF HAEMATOLOGY
Year: 2009
Reference: Br J Haematol. 2009 Nov;147(3):289-96.
Impact factor: 4.478
Publication type: Review in international publication
Authors: , , , et al.
DOI: 10.1111/j.1365-2141.2009.07831.x

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