About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
We are dedicated to investigate transfusional activity, the alteration of erythrocytes during the conservation period and extracorporeal photoapheresis. We work on the molecular and serological characterization of blood group variants. In non-invasive fetal genotyping strategies due to blood group incompatibilities. We develop iPSC lines and produce in vitro erythrocytes with rare phenotypes. We deepen in the knowledge of epidemiology and the detection of infectious agents relevant for safety of the products supplied by the Blood and Tissue Bank.
We investigate in clinical immunology and develop our own HLA and KIR typing protocols. We develop and incorporate new therapeutic applications in cell therapy including hematopoietic transplantation, cellular immunology and regenerative medicine. We investigate the molecular mechanisms and genotype-phenotype correlation of coagulopathies, haemorrhagic diathesis and other associated congenital pathologies. We develop tools based on the new technologies of parallel massive sequencing with application to the molecular study, genetic counselling and prenatal diagnosis.
Molecular and serological characterization of blood group variants. Non-invasive fetal genotyping strategies due to blood group incompatibilities. Development of iPSC lines and production of in vitro red blood cells with rare erythrocytic phenotypes.
PI: Muñiz Diaz, Eduardo
Researchers:
Nogués Gálvez, Núria
Canals Surís, Carme
González Santesteban, Cecilia
Miquel Serra, Eulàlia
IP: Immunohematologia
Investigation in transfusional activity, the alteration of red blood cells during the conservation period and the usefulness of extracorporeal photoapheresis.
PI: Parra López, Rafael
Researchers in training
Rodríguez Aliberas, Marta
Fernández Sojo, Jesus
IP: Rafael Parra López
IP: Joan García López Collaborators: Sergi Querol Giner, Joaquim Vives Armengol, Luciano Rodríguez Gómez, Francesc Rudilla Salvador, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol, Joaquim Vives Armengol Funding agency: Instituto de Salud Carlos III Funding: 338472.2 Reference: RD21/0017/0022 Duration: 01/01/2022 - 31/12/2024
IP: Juan Ignacio Esteban Mur Collaborators: Lluís Viladomiu Catà, Silvia Sauleda Oliveras, Jordi Llaneras Artigues, Marta Bes Maijo, Cristina Dopazo Taboada, Angie Rico Blazquez Funding agency: Instituto de Salud Carlos III Funding: 159720 Reference: PI19/00533 Duration: 01/01/2020 - 30/06/2024
IP: José Manuel Vidal Taboada Collaborators: Maria Jose Herrero Mata, Maria Salvadó Figueras, Josep Gamez Carbonell, Consuelo Garcia Carmona, Arnau Llauradó Gayete Funding agency: Instituto de Salud Carlos III Funding: 117370 Reference: PI19/00593 Duration: 01/01/2020 - 30/06/2024
IP: - Collaborators: Beatriz Lobo Alvarez, Merce Albert Bayo, Inés de Torres Ramirez, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Xavier Serra Ruiz Funding agency: Instituto de Salud Carlos III Funding: 183920 Reference: PI19/01643 Duration: 01/01/2020 - 30/06/2024
PMID: 37569568 Journal: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Year: 2023 Reference: Int J Mol Sci. 2023 Jul 29;24(15):12183. doi: 10.3390/ijms241512183. Impact factor: Publication type: Paper in international publication Authors: Bes, Marta; Borras, Francesc E; Burgui, Idoia; Camos, Silvia; Corrales, Irene; Costafreda, Maria Isabel; Domingo, Esteban; Esteban, Juan Ignacio; Llorens-Revull, Meritxell; Martinez-Gonzalez, Brenda et al. DOI: 10.3390/ijms241512183
PMID: 37696499 Journal: BRITISH JOURNAL OF HAEMATOLOGY Year: 2023 Reference: Br J Haematol. 2023 Sep 11. doi: 10.1111/bjh.19050. Impact factor: Publication type: Letter or abstract Authors: Bandini, Perla; Borras, Nina; Cadahia Fernandez, Patricia; Comes, Natalia; Corrales, Irene; Fernandez Mellid, Eugenia; Martin-Fernandez, Laura; Melero Valentin, Paula; Perez Encinas, Manuel Mateo; Ramirez, Lorena et al. DOI: 10.1111/bjh.19050
PMID: 37715777 Journal: CYTOTHERAPY Year: 2023 Reference: Cytotherapy. 2023 Sep 15:S1465-3249(23)01039-3. doi: 10.1016/j.jcyt.2023.08.008. Impact factor: Publication type: Paper in international publication Authors: Aran, Gemma; Castano, Julio; Coca, Maria Isabel; Codinach, Margarita; Lopez-Fernandez, Alba; Prat-Vidal, Cristina; Querol, Sergi; Rodriguez, Luciano; Torrents, Silvia; Vives, Joaquim et al. DOI: 10.1016/j.jcyt.2023.08.008
PMID: 37726066 Journal: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Year: 2023 Reference: Int J Infect Dis. 2023 Sep 17:S1201-9712(23)00722-1. doi: 10.1016/j.ijid.2023.09.009. Impact factor: Publication type: Paper in international publication Authors: Alvarez-Lopez, Patricia; Alvarez-Lopez, Patricia; Arando, Maider; Arando, Maider; Burgos, Joaquin; Burgos, Joaquin; Buzon, Maria Jose; Buzon, Maria Jose; Curran, Adrian; Curran, Adrian et al. DOI: 10.1016/j.ijid.2023.09.009
PMID: 33849662 Journal: Stem Cell Research & Therapy Year: 2021 Reference: Stem Cell Res Ther. 2021 Apr 13;12(1):233. doi: 10.1186/s13287-021-02301-0. Impact factor: 6.832 Publication type: Paper in international publication Authors: Querol, Sergi, Rudilla, Francesc, Herrero, Maria Jose, Alvarez-Palomo, Belen, Garcia-Martinez, Iris, Gayoso, Jorge, Raya, Angel, Veiga, Anna, Abad, Maria Luisa, Eiras, Adolfo et al. DOI: 10.1186/s13287-021-02301-0
PMID: 33780553 Journal: JOURNAL OF CLINICAL APHERESIS Year: 2021 Reference: J Clin Apher. 2021 Aug;36(4):563-573. doi: 10.1002/jca.21894. Epub 2021 Mar 29. Impact factor: 2.821 Publication type: Paper in international publication Authors: Salinas, Ramon, Salgado-Barreira, Angel, Fernandez-Docampo, Marta, Pascual-Izquierdo, Cristina, Del Rio-Garma, Julio, de la Rubia, Javier, Viejo, Aurora, Mingot, Eva, Cid, Joan, Solanich, Xavier et al. DOI: 10.1002/jca.21894
PMID: 33621399 Journal: STEM CELLS Year: 2021 Reference: Stem Cells. 2021 Jul;39(7):866-881. doi: 10.1002/stem.3358. Epub 2021 Mar 3. Impact factor: 6.277 Publication type: Paper in international publication Authors: Edel, Michael J, Esteller, Manel, Perez, Francisco Vidal, Alvarez-Palomo, Ana Belen, Requena-Osete, Jordi, Delgado-Morales, Raul, Moreno-Manzano, Victoria, Grau-Bove, Carme, Tejera, Agueda M, Otero, Manel Juan et al. DOI: 10.1002/stem.3358
PMID: 33581698 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2021 Reference: Thromb Haemost. 2021 Nov;121(11):1400-1408. doi: 10.1055/s-0040-1722623. Epub 2021 Feb 13. Impact factor: 5.723 Publication type: Paper in international publication Authors: Oldenburg, Johannes, Liesner, Ri J, Abraham, Aby, Altisent, Carmen, Belletrutti, Mark J, Carcao, Manuel, Carvalho, Manuela, Chambost, Herve, Chan, Anthony K C, Dubey, Leonid et al. DOI: 10.1055/s-0040-1722623
PMID: 32726853 Journal: THROMBOSIS AND HAEMOSTASIS Year: 2020 Reference: Thromb Haemost. 2020 Oct;120(10):1395-1406. doi: 10.1055/s-0040-1714214. Epub 2020 Jul 29. Impact factor: 4.379 Publication type: Paper in international publication Authors: Vidal, Francisco, Alonso, Sofia, Corrales, Irene, Megias-Vericat, Juan Eduardo, Garcia-Martinez, Iris, Borras, Nina, Martorell, Marta, Parra, Rafael, Altisent, Carme, Ramirez, Lorena et al. DOI: 10.1055/s-0040-1714214
PMID: 32542961 Journal: HAEMOPHILIA Year: 2020 Reference: Haemophilia. 2020 Jul;26(4):637-642. doi: 10.1111/hae.14018. Epub 2020 Jun 15. Impact factor: 2.99 Publication type: Paper in international publication Authors: Chan, Anthony, Altisent, Carmen, Seifert, Wilfried, Santagostino, Elena, Kenet, Gili, Boggio, Lisa, Mancuso, Maria Elisa, Oldenburg, Johannes et al. DOI: 10.1111/hae.14018
PMID: 32304998 Journal: EBioMedicine Year: 2020 Reference: EBioMedicine. 2020 Apr;54:102729. doi: 10.1016/j.ebiom.2020.102729. Epub 2020 Apr 15. Impact factor: 5.736 Publication type: Paper in international publication Authors: Coca, Maria Isabel, Reales, Laura, Camara-Rosell, Maria Luisa, Cediel, German, Coll, Ruth, Farre, Ramon, Navajas, Daniel, Vilarrodona, Anna, Garcia-Lopez, Joan, Munoz-Guijosa, Christian et al. DOI: 10.1016/j.ebiom.2020.102729
PMID: 32161589 Journal: Frontiers in Immunology Year: 2020 Reference: Front Immunol. 2020 Feb 25;11:271. doi: 10.3389/fimmu.2020.00271. eCollection 2020. Impact factor: 5.085 Publication type: Paper in international publication Authors: Grau-Vorster, Marta, Lopez-Montanes, Maria, Canto, Ester, Vives, Joaquim, Oliver-Vila, Irene, Barba, Pere, Querol, Sergi, Rudilla, Francesc et al. DOI: 10.3389/fimmu.2020.00271
PMID: 31043424 Journal: BLOOD Year: 2019 Reference: Blood. 2019 Jun 13;133(24):2618-2622. doi: 10.1182/blood.2019000055. Epub 2019 May 1. Impact factor: 16.562 Publication type: Paper in international publication Authors: Vidal, Francisco, Bauduer, Frederic, Carbonell, Pablo, Corral, Javier, Vicente, Vicente, Parra, Rafael, Padilla, Jose, de la Morena-Barrio, Maria Eugenia, Salloum-Asfar, Salam, Esteban, Julio et al. DOI: 10.1182/blood.2019000055
PMID: 30965661 Journal: Journal of Clinical Medicine Year: 2019 Reference: J Clin Med. 2019 Apr 8;8(4). pii: jcm8040476. doi: 10.3390/jcm8040476. Impact factor: 5.688 Publication type: Review in international publication Authors: Alvarez-Palomo, Belen, Vives, Joaquim, Casaroli-Marano, Ricardo P P, G Gomez, Susana G, Rodriguez Gomez, Luciano, Edel, Michael J, Querol Giner, Sergi et al. DOI: 10.3390/jcm8040476
PMID: 30361419 Journal: HAEMATOLOGICA Year: 2019 Reference: Haematologica. 2019 Mar;104(3):587-598. doi: 10.3324/haematol.2018.203166. Epub 2018 Oct 25. Impact factor: 7.57 Publication type: Paper in international publication Authors: Borras, Nina, Orriols, Gerard, Batlle, Javier, Perez-Rodriguez, Almudena, Fidalgo, Teresa, Martinho, Patricia, Lopez-Fernandez, Maria Fernanda, Rodriguez-Trillo, Angela, Loures, Esther, Castro Quismondo, Nerea et al. DOI: 10.3324/haematol.2018.203166
PMID: 30503040 Journal: JOURNAL OF HEPATOLOGY Year: 2019 Reference: J Hepatol. 2019 Mar;70(3):564-566. doi: 10.1016/j.jhep.2018.10.020. Epub 2018 Nov 28. Impact factor: 18.946 Publication type: Letter or abstract Authors: Riveiro-Barciela, Mar, Munoz-Couselo, Eva, Fernandez-Sojo, Jesus, Diaz-Mejia, Nely, Parra-Lopez, Rafael, Buti, Maria et al. DOI: 10.1016/j.jhep.2018.10.020
PMID: 29030947 Journal: HLA Year: 2018 Reference: HLA. 2018 Jan;91(1):69-70. doi: 10.1111/tan.13159. Epub 2017 Nov 13. Impact factor: 2.558 Publication type: Paper in international publication Authors: Enrich, E, Campos, E, Caro-Oleas, J L, Herrero-Mata, M J, Rudilla, F et al. DOI: 10.1111/tan.13159
PMID: 29135082 Journal: HLA Year: 2018 Reference: HLA. 2018 Feb;91(2):140-141. doi: 10.1111/tan.13174. Epub 2017 Dec 5. Impact factor: 2.558 Publication type: Paper in international publication Authors: Enrich, E, Herrero-Mata, M J, Rudilla, F, Caro-Oleas, J L, Mongay, L et al. DOI: 10.1111/tan.13174
PMID: 29732654 Journal: HAEMOPHILIA Year: 2018 Reference: Haemophilia. 2018 May;24(3):e163-e166. doi: 10.1111/hae.13499. Epub 2018 May 6. Impact factor: 2.768 Publication type: Review in international publication Authors: Pardos-Gea, J, Fernandez-Diaz, N, Parra, R, Cortina, V, Altisent, C et al. DOI: 10.1111/hae.13499
PMID: 29578308 Journal: HAEMOPHILIA Year: 2018 Reference: Haemophilia. 2018 May;24(3):e136-e139. doi: 10.1111/hae.13462. Epub 2018 Mar 26. Impact factor: 2.768 Publication type: Letter or abstract Authors: Aznar, J A, Altisent, C, Alvarez-Roman, M T, Bonanad, S, Mingot-Castellano, M E, Lopez, M F et al. DOI: 10.1111/hae.13462
PMID: 26969334 Journal: CLINICAL THERAPEUTICS Year: 2016 Reference: Clin Ther. 2016 Apr;38(4):936-44. doi: 10.1016/j.clinthera.2016.02.015. Epub 2016 Mar 8. Impact factor: 2.925 Publication type: Paper in international publication Authors: Korth-Bradley, Joan M, Rendo, Pablo, Smith, Lynne, Altisent, Carmen et al. DOI: 10.1016/j.clinthera.2016.02.015
PMID: 27228069 Journal: HAEMOPHILIA Year: 2016 Reference: Haemophilia. 2016 Jul;22(4):e324-7. doi: 10.1111/hae.12948. Epub 2016 May 26. Impact factor: 2.673 Publication type: Letter or abstract Authors: Altisent, C, Martorell, M, de la Sierra, A et al. DOI: 10.1111/hae.12948
PMID: 26207933 Journal: HAEMOPHILIA Year: 2016 Reference: Haemophilia. 2016 Jan;22(1):110-20. doi: 10.1111/hae.12763. Epub 2015 Jul 24. Impact factor: 2.673 Publication type: Paper in international publication Authors: Zulfikar, B, Windyga, J, Rocino, A, Richards, M, Perez, R, Windyga, J, Dolan, G, Altisent, C, Katsarou, O, Lopez Fernandez, M-F et al. DOI: 10.1111/hae.12763
PMID: 26315845 Journal: HAEMOPHILIA Year: 2016 Reference: Haemophilia. 2016 Mar;22(2):218-224. doi: 10.1111/hae.12792. Epub 2015 Aug 28. Impact factor: 2.673 Publication type: Paper in international publication Authors: Altisent, C, Martorell, M, Crespo, A, Casas, L, Torrents, C, Parra, R et al. DOI: 10.1111/hae.12792
