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Translational Immunology

The main objectives are to improve the diagnosis of immunodeficiencies and autoimmune diseases, addressing also their heterogeneity and mechanisms in close collaboration with the pediatrics, thyroid and systemic disease groups, being internationally recognized in both areas. The group participates in numerous research projects at the Vall d'Hebron Barcelona Hospital Campus that use immunological tests developed for specific projects led by the kidney transplantation, intensive care medicine, internal medicine, allergy and rheumatology groups. During the COVID pandemic the group made contributions in improving the immunogenetic and immunological risk profiles and in the evaluation of the immune response to vaccination and natural infection, collaborating with national and international networks. The group has also generated a biobank of more than 8.000 samples from patients with COVID-19 that have been incorporated into the VHIR biobank.

The group works as a coordinator of the "Focis" Center of Excellence (Federation of Clinical Immunology Societies) of Barcelona.

Team

Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
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Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
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Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
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Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
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Romina Dieli Crimi

Romina Dieli Crimi

Senior researcher
Translational Immunology
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Sergi Cantenys Molina

Sergi Cantenys Molina

Predoctoral researcher
Translational Immunology
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Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
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Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
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Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
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Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
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Romina Dieli Crimi

Romina Dieli Crimi

Senior researcher
Translational Immunology
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Sergi Cantenys Molina

Sergi Cantenys Molina

Predoctoral researcher
Translational Immunology
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Projects

Caracterización transcriptómica, epigenética y funcional de pacientes con síndrome hemofagocífico secundario.

IP: Mónica Martínez Gallo
Collaborators: Gemma Vila Pijoan, Sandra Salgado Perandres, Adolfo Ruiz Sanmartin, Montserrat Pujol Jover, Estefania Moreno Ruzafa, Jacques Gabriel Rivière
Funding agency: Instituto de Salud Carlos III
Funding: 117370
Reference: PI18/00346
Duration: 01/01/2019 - 30/06/2023

Identificación de biomarcadores celulares y moleculares en angioedema idiopático y hereditario para su diferenciación en fenotipos y endotipos

IP: Mar Guilarte Clavero
Collaborators: Manuel Hernández González, Moisés Labrador Horrillo, Anna Sala Cunill, Olga Luengo Sanchez, Paula Galvan Blasco, Ingrid Johana Gil Serrano
Funding agency: Instituto de Salud Carlos III
Funding: 84700
Reference: PI20/01061
Duration: 01/01/2021 - 30/06/2025

Integrating genome and transcriptome profiling for the identification of novel genetic basis of primary immunodeficiencies.

IP: Roger Colobran Oriol
Collaborators: Aina Aguiló Cucurull, Andrea Martín Nalda, Laura Batlle Masó
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI20/00761
Duration: 01/01/2021 - 30/06/2025

Synthetic diagnostic device to substitute animal erythrocytes in classical haemagglutination assays: application to influenza virus surveillance.

IP: Eva Baldrich Rubio
Collaborators: Romina Dieli Crimi, Mónica Martínez Gallo, Andres Antón Pagarolas, Tomàs Pumarola Suñé, Cristina Andrés Vergés
Funding agency: Instituto de Salud Carlos III
Funding: 104500
Reference: DTS20/00093
Duration: 01/01/2021 - 30/06/2023

Blog

News

A Vall d’Hebron team demonstrates, for the first time, the potential of optical genome mapping to detect genetic alterations associated with this rare disease that are not identified using conventional methods.

The study describes the first documented case worldwide of hereditary angioedema transmission through assisted reproduction.

The paper describes the case of a patient in whom, years after a bone marrow transplant, two immune cell lines corrected the original genetic defect.