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Translational Immunology

The main objectives are to improve the diagnosis of immunodeficiencies and autoimmune diseases, addressing also their heterogeneity and mechanisms in close collaboration with the pediatrics, thyroid and systemic disease groups, being internationally recognized in both areas. The group participates in numerous research projects at the Vall d'Hebron Barcelona Hospital Campus that use immunological tests developed for specific projects led by the kidney transplantation, intensive care medicine, internal medicine, allergy and rheumatology groups. During the COVID pandemic the group made contributions in improving the immunogenetic and immunological risk profiles and in the evaluation of the immune response to vaccination and natural infection, collaborating with national and international networks. The group has also generated a biobank of more than 8.000 samples from patients with COVID-19 that have been incorporated into the VHIR biobank.

The group works as a coordinator of the "Focis" Center of Excellence (Federation of Clinical Immunology Societies) of Barcelona.

Team

Maria Teresa  Sanz Martinez

Maria Teresa Sanz Martinez

Predoctoral researcher
Translational Immunology
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Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
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Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
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Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
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Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
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Romina Dieli Crimi

Romina Dieli Crimi

Translational Immunology
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Maria Teresa  Sanz Martinez

Maria Teresa Sanz Martinez

Predoctoral researcher
Translational Immunology
Read more
Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
Read more
Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
Read more
Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
Read more
Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
Read more
Romina Dieli Crimi

Romina Dieli Crimi

Translational Immunology
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Projects

Acreditació AGAUR grup d'infecció en el pacient pediàtric immunodeprimit

IP: Pere Soler Palacín
Collaborators: Antoni Soriano Arandes, Jorgina Vila Soler, Laura Batlle Masó, Natalia Ana Mendoza Palomar, Maria Espiau Guarner, Aurora Fernandez Polo, Núria Worner Tomasa, Laura Lopez Seguer, Miriam Gonzalez Amores, Susana Melendo Perez, Sonia Rodriguez Tello, Andrea Martín Nalda, Claudia Broto Cortes, Marie Antoinette Frick, Jacques Gabriel Rivière
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00441
Duration: 01/01/2022 - 30/06/2025

Estudio de expresión de antígenos en tejido tumoral de pacientes con Esclerosis Sistémica.

IP: Alfredo Guillen Del Castillo
Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/01804
Duration: 01/01/2023 - 31/12/2025

Identificación de biomarcadores celulares y moleculares en angioedema idiopático y hereditario para su diferenciación en fenotipos y endotipos

IP: Mar Guilarte Clavero
Collaborators: Manuel Hernández González, Moisés Labrador Horrillo, Anna Sala Cunill, Olga Luengo Sanchez, Paula Galvan Blasco, Ingrid Johana Gil Serrano
Funding agency: Instituto de Salud Carlos III
Funding: 84700
Reference: PI20/01061
Duration: 01/01/2021 - 30/06/2025

Integrating genome and transcriptome profiling for the identification of novel genetic basis of primary immunodeficiencies.

IP: Roger Colobran Oriol
Collaborators: Aina Aguiló Cucurull, Andrea Martín Nalda, Laura Batlle Masó
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI20/00761
Duration: 01/01/2021 - 30/06/2025

Blog

News

The paper describes the case of a patient in whom, years after a bone marrow transplant, two immune cell lines corrected the original genetic defect.

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.