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Translational Immunology

The main objectives are to improve the diagnosis of immunodeficiencies and autoimmune diseases, addressing also their heterogeneity and mechanisms in close collaboration with the pediatrics, thyroid and systemic disease groups, being internationally recognized in both areas. The group participates in numerous research projects at the Vall d'Hebron Barcelona Hospital Campus that use immunological tests developed for specific projects led by the kidney transplantation, intensive care medicine, internal medicine, allergy and rheumatology groups. During the COVID pandemic the group made contributions in improving the immunogenetic and immunological risk profiles and in the evaluation of the immune response to vaccination and natural infection, collaborating with national and international networks. The group has also generated a biobank of more than 8.000 samples from patients with COVID-19 that have been incorporated into the VHIR biobank.

The group works as a coordinator of the "Focis" Center of Excellence (Federation of Clinical Immunology Societies) of Barcelona.

Team

Sergi Cantenys Molina

Sergi Cantenys Molina

Translational Immunology
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Daniel Alvarez De la Sierra

Daniel Alvarez De la Sierra

Research technician
Translational Immunology
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Iria Arrese Muñoz

Iria Arrese Muñoz

Predoctoral researcher
Translational Immunology
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Janire Perurena Prieto

Janire Perurena Prieto

Predoctoral researcher
Translational Immunology
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Sergi Cantenys Molina

Sergi Cantenys Molina

Translational Immunology
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Daniel Alvarez De la Sierra

Daniel Alvarez De la Sierra

Research technician
Translational Immunology
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Iria Arrese Muñoz

Iria Arrese Muñoz

Predoctoral researcher
Translational Immunology
Read more
Janire Perurena Prieto

Janire Perurena Prieto

Predoctoral researcher
Translational Immunology
Read more

Projects

Determinació de biomarcadors mitjançant anàlisi transcriptòmica per a la diferenciació en fenotips i endotips de pacients amb angioedema idiopàtic i angioedema hereditari

IP: Ingrid Johana Gil Serrano
Collaborators: -
Funding agency: Stat. Catalana d'Al·lèrgia i Immunologia Clínica
Funding: 9000
Reference: SCAIC/BEQUES/2020/GIL
Duration: 01/06/2020 - 01/01/2025

Caracterización de Neisseria meningitidis tras la introducción de la vacuna frente al serogrupo B e identificación de factores predisponentes para la enfermedad meningocócica invasiva

IP: Juan Jose Gonzalez Lopez
Collaborators: Manuel Hernández González, Jose Angel Rodrigo Pendás, Maria Belén Viñado Perez, Aina Aguiló Cucurull, Alba Mir Cros, Albert Moreno Mingorance, Andrea Martín Nalda, Nuria Serre Delcor, Josep Roca Grande, Laura Batlle Masó
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI21/00132
Duration: 01/01/2022 - 30/06/2026

UNDINE: The human genetic and immunological determinants of the clinical manifestations of SARS-CoV-2 infection: Towards personalised medicine

IP: Pere Soler Palacín
Collaborators: Laura Batlle Masó
Funding agency: EUROPEAN COMMISSION
Funding: 163667.5
Reference: UNDINE_HE-HLTH-DISEASE21
Duration: 01/06/2022 - 31/05/2026

Blog

News

The paper describes the case of a patient in whom, years after a bone marrow transplant, two immune cell lines corrected the original genetic defect.

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.