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Translational Immunology

The main objectives are to improve the diagnosis of immunodeficiencies and autoimmune diseases, addressing also their heterogeneity and mechanisms in close collaboration with the pediatrics, thyroid and systemic disease groups, being internationally recognized in both areas. The group participates in numerous research projects at the Vall d'Hebron Barcelona Hospital Campus that use immunological tests developed for specific projects led by the kidney transplantation, intensive care medicine, internal medicine, allergy and rheumatology groups. During the COVID pandemic the group made contributions in improving the immunogenetic and immunological risk profiles and in the evaluation of the immune response to vaccination and natural infection, collaborating with national and international networks. The group has also generated a biobank of more than 8.000 samples from patients with COVID-19 that have been incorporated into the VHIR biobank.

The group works as a coordinator of the "Focis" Center of Excellence (Federation of Clinical Immunology Societies) of Barcelona.

Team

Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
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Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
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Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
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Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
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Romina Dieli Crimi

Romina Dieli Crimi

Senior researcher
Translational Immunology
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Sergi Cantenys Molina

Sergi Cantenys Molina

Predoctoral researcher
Translational Immunology
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Aina Aguiló Cucurull

Aina Aguiló Cucurull

Research technician
Translational Immunology
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Sandra Salgado Perandres

Sandra Salgado Perandres

Research technician
Translational Immunology
Read more
Blanca Angélica Urban Vargas

Blanca Angélica Urban Vargas

Predoctoral researcher
Translational Immunology
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Carlos Abel Salazar Valle

Carlos Abel Salazar Valle

Translational Immunology
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Romina Dieli Crimi

Romina Dieli Crimi

Senior researcher
Translational Immunology
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Sergi Cantenys Molina

Sergi Cantenys Molina

Predoctoral researcher
Translational Immunology
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Projects

La interacción entre el error innato de la inmunidad y los trastornos sanguíneos: desentrañando los defectos inmunitarios detrás de las enfermedades hematológicas comunes

IP: Pere Soler Palacín
Collaborators: Laura Batlle Masó, Maria Cristina Díaz de Heredia Rubio, Roger Colobran Oriol, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Miriam Gonzalez Amores, Janire Perurena Prieto, Andrea Martín Nalda, Lucas Moreno Martín-Retortillo, Jacques Gabriel Rivière
Funding agency: Instituto de Salud Carlos III
Funding: 179993.75
Reference: AC23_2/00033
Duration: 01/01/2024 - 31/12/2026

Identification and functional characterization of structural variants in patients with inborn errors of immunity

IP: Roger Colobran Oriol
Collaborators: Romina Dieli Crimi, Aina Aguiló Cucurull, Laura Batlle Masó, Andrea Martín Nalda, Neus Castells Sarret
Funding agency: Instituto de Salud Carlos III
Funding: 208750
Reference: PI23/00161
Duration: 01/01/2024 - 30/06/2028

Estudio de expresión de antígenos en tejido tumoral de pacientes con Esclerosis Sistémica.

IP: Alfredo Guillen Del Castillo
Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/01804
Duration: 01/01/2023 - 30/06/2027

Caracterización de Neisseria meningitidis tras la introducción de la vacuna frente al serogrupo B e identificación de factores predisponentes para la enfermedad meningocócica invasiva

IP: Juan Jose Gonzalez Lopez
Collaborators: Manuel Hernández González, Jose Angel Rodrigo Pendás, Maria Belén Viñado Perez, Aina Aguiló Cucurull, Laura Batlle Masó, Alba Mir Cros, Nuria Serre Delcor, Albert Moreno Mingorance, Josep Roca Grande, Andrea Martín Nalda
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI21/00132
Duration: 01/01/2022 - 30/06/2026

Blog

News

A Vall d’Hebron team demonstrates, for the first time, the potential of optical genome mapping to detect genetic alterations associated with this rare disease that are not identified using conventional methods.

The study describes the first documented case worldwide of hereditary angioedema transmission through assisted reproduction.

The paper describes the case of a patient in whom, years after a bone marrow transplant, two immune cell lines corrected the original genetic defect.