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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Team

Santiago Ramon y Cajal Agüeras

Santiago Ramon y Cajal Agüeras

Head of group
Translational Molecular Pathology
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Stefan Huemmer

Stefan Huemmer

Main researcher
Translational Molecular Pathology
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Trond Aasen

Trond Aasen

Main researcher
Translational Molecular Pathology
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Ximena Garcia Torres

Ximena Garcia Torres

Administration and Management
Translational Molecular Pathology
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Santiago Ramon y Cajal Agüeras

Santiago Ramon y Cajal Agüeras

Head of group
Translational Molecular Pathology
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Stefan Huemmer

Stefan Huemmer

Main researcher
Translational Molecular Pathology
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Trond Aasen

Trond Aasen

Main researcher
Translational Molecular Pathology
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Ximena Garcia Torres

Ximena Garcia Torres

Administration and Management
Translational Molecular Pathology
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Projects

GC16173720CARR Definición de mecanismos clave de la multiresistencia de tumores de cabeza y cuello a los tratamientos quimio- y radioterapéuticos. Identificación de nuevos antitumorales individualizados.

IP: Matilde Lleonart Pajarin
Collaborators: Yoelsis Garcia Mayea, Juan Lorente Guerrero, Sergio Benavente Norza, Josep Castellví Vives, Vicente Peg Camara, GC16173720CARR Definición de mecanismos clave de la multiresistencia de tumores de cabeza y cuello a los tratamientos quimio- y
Funding agency: Asociación Española Contra el Cáncer
Funding: 380000
Reference: AECC/GCE/2016/LLEONART
Duration: 01/10/2016 - 30/09/2022

ITACAT: Impact of Thrombus Analysis in stroke patients in CATalonia.

IP: Carlos Molina Cateriano
Collaborators: Santiago Ramon y Cajal Agüeras, Jorge Pagola Pérez Blanca, Carlos Palacio García, Noelia Rodríguez Villatoro, David Rodriguez Luna
Funding agency: Fundació La Marató de TV3
Funding: 197973.69
Reference: 20171930
Duration: 01/01/2018 - 31/01/2022

Estudio de la cooperación clonal (heterogeneidad intratumoral) in vitro e in vivo en carcinomas: papel de los exosomas y estudio de los factores secretados

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Maria Rosa Somoza Lopez de Haro, Teresa Moline Marimon, Josep Castellví Vives, Stefan Hummer
Funding agency: Instituto de Salud Carlos III
Funding: 123420
Reference: PI17/02247
Duration: 01/01/2018 - 31/12/2020

nTRACK: Multimodal nanoparticles for structural and functional tracking of stem cell therapy on muscle regeneration..

IP: José Raul Herance Camacho
Collaborators: Ana Lain Fernandez, Vicenç Martínez Ibáñez, Laura Vidal Fornells, Carlos Giné Prades, Roso Marès Pagès, Carolina Aparicio Gomez, nTRACK: Multimodal nanoparticles for structural and functional tracking of stem cell therapy on muscle regeneration.., nTRACK: Multimodal nanoparticles for structural and functional tracking of stem cell therapy on muscle regeneration.., Mario Marotta Baleriola, Itziar Busquets Saez, Manuel López Paredes
Funding agency: EUROPEAN COMMISSION
Funding: 1063437.5
Reference: NTRACK_H2020NMBP2017
Duration: 01/10/2017 - 31/03/2022

Blog

News

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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