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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Publications

Transarticular epithelioid hemangioma of the ankle-a case of a rare vascular neoplasm.

PMID: 33420574
Journal: SKELETAL RADIOLOGY
Year: 2021
Reference: Skeletal Radiol. 2021 Jun;50(6):1263-1270. doi: 10.1007/s00256-020-03687-3. Epub 2021 Jan 8.
Impact factor: 2.199
Publication type: Letter or abstract
Authors: Marton, Nikolett, Ramos-Oliver, Irma, Cajal, Alfredo Gimeno, de Albert, Matias, Dominguez Oronoz, Rosa et al.
DOI: 10.1007/s00256-020-03687-3

Progression of Interstitial Fibrosis and Tubular Atrophy in Low Immunological Risk Renal Transplants Monitored by Sequential Surveillance Biopsies: The Influence of TAC Exposure and Metabolism.

PMID: 33406589
Journal: Journal of Clinical Medicine
Year: 2021
Reference: J Clin Med. 2021 Jan 4;10(1). pii: jcm10010141. doi: 10.3390/jcm10010141.
Impact factor: 4.242
Publication type: Paper in international publication
Authors: Chamoun, Betty, Torres, Irina B, Gabaldon, Alejandra, Sellares, Joana, Perello, Manel, Castella, Eva, Guri, Xavier, Salcedo, Maite, Toapanta, Nestor G, Cidraque, Ignacio et al.
DOI: 10.3390/jcm10010141

Clinical, pathological, and PAM50 gene expression features of HER2-low breast cancer.

PMID: 33397968
Journal: npj Breast Cancer
Year: 2021
Reference: NPJ Breast Cancer. 2021 Jan 4;7(1):1. doi: 10.1038/s41523-020-00208-2.
Impact factor: 6.923
Publication type: Paper in international publication
Authors: Lluch, Ana, Chic, Nuria, Braso-Maristany, Fara, Pare, Laia, Pascual, Tomas, Conte, Benedetta, Martinez-Saez, Olga, Adamo, Barbara, Vidal, Maria, Barnadas, Esther et al.
DOI: 10.1038/s41523-020-00208-2

Blog

News

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

On World Cancer Research Day, we highlight research aimed at improving treatments for both pediatric and adult cancers through innovative techniques.

On World Cancer Research Day, we highlight the oncology research model of the Vall d'Hebron Campus that allows laboratory results to be transferred as quickly as possible to clinical practice.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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