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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Team

Josep Castellví Vives

Josep Castellví Vives

Translational Molecular Pathology
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Marta Cano Galietero

Marta Cano Galietero

Research technician
Translational Molecular Pathology
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Marta Sese Faustino

Marta Sese Faustino

Postdoctoral researcher
Translational Molecular Pathology
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Mercedes Martinez Mansilla

Mercedes Martinez Mansilla

Research technician
Translational Molecular Pathology
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Santiago Ramon y Cajal Agüeras

Santiago Ramon y Cajal Agüeras

Head of group
Translational Molecular Pathology
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Stefan Huemmer

Stefan Huemmer

Main researcher
Translational Molecular Pathology
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Josep Castellví Vives

Josep Castellví Vives

Translational Molecular Pathology
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Marta Cano Galietero

Marta Cano Galietero

Research technician
Translational Molecular Pathology
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Marta Sese Faustino

Marta Sese Faustino

Postdoctoral researcher
Translational Molecular Pathology
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Mercedes Martinez Mansilla

Mercedes Martinez Mansilla

Research technician
Translational Molecular Pathology
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Santiago Ramon y Cajal Agüeras

Santiago Ramon y Cajal Agüeras

Head of group
Translational Molecular Pathology
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Stefan Huemmer

Stefan Huemmer

Main researcher
Translational Molecular Pathology
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Projects

New therapeutic approaches in head and neck cancer

IP: Matilde Lleonart Pajarin
Collaborators: Irene Braña Garcia, Yoelsis Garcia Mayea, Jordi Temprana Salvador, Angel García Jiménez, Sergio Benavente Norza, Josep Castellví Vives, Laia Josa Culleré, Marina Bataller Fernández
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI20/00556
Duration: 01/01/2021 - 30/06/2025

Oncogene-mediated intratumoral immune-cell populations at different organs as biomarkers of immunotherapy response

IP: Juan Angel Recio Conde
Collaborators: Paula Granado Martinez, Kimberley Anne McGrail Fernández, Vicente García-Patos Briones, Berta Ferrer Fábrega, Sara Garcia Ortega, Eva Muñoz Couselo
Funding agency: Instituto de Salud Carlos III
Funding: 341220
Reference: PI20/00384
Duration: 01/01/2021 - 30/04/2024

Implicaction of proteins associated with vascular beta-amyloid in Cerebral Amyloid Angiopathy

IP: Maria Mar Hernandez Guillamon
Collaborators: Jessica Camacho Soriano, Olga Maisterra Santos, Olalla Pancorbo Rosal
Funding agency: Instituto de Salud Carlos III
Funding: 169400
Reference: PI20/00465
Duration: 01/01/2021 - 30/06/2025

Protuberancias intercelulares reguladas por Cx43 en cáncer: elucidación funcional, descubrimiento de objetivos, desarrollo de biomarcadores y detección de tumores

IP: Trond Aasen
Collaborators: Maria Rosa Somoza Lopez de Haro, Jordi Temprana Salvador, Teresa Moline Marimon, Marta Sese Faustino, Irene Sansano Valero, Stefan Hummer
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI21/00470
Duration: 01/01/2022 - 30/06/2026

Blog

News

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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