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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Team

Trond Aasen

Trond Aasen

Main researcher
Translational Molecular Pathology
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Ximena Garcia Torres

Ximena Garcia Torres

Administration and Management
Translational Molecular Pathology
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Trond Aasen

Trond Aasen

Main researcher
Translational Molecular Pathology
Read more
Ximena Garcia Torres

Ximena Garcia Torres

Administration and Management
Translational Molecular Pathology
Read more

Projects

Inmunomonitorización personalizada para estratificar los pacientes con lupus eritematoso sistémico

IP: Josefina Cortes Hernandez
Collaborators: Teresa Moline Marimon, Sheila Bermejo Garcia
Funding agency: Instituto de Salud Carlos III
Funding: 141570
Reference: PI21/00287
Duration: 01/01/2022 - 31/12/2024

Next generation personalised medicine for childhood cancers

IP: Lucas Moreno Martín-Retortillo
Collaborators: Aroa Soriano Fernández, Jessica Camacho Soriano, Raquel Hladun Alvaro, Gabriela Guillén Burrieza, Andrea Vilaplana Blanes, Lorena Valero Arrese, Mariona Morell Daniel
Funding agency: Instituto de Salud Carlos III
Funding: 214170
Reference: PI21/01661
Duration: 01/01/2022 - 30/06/2026

Aislamiento y caracterización molecular de Células Tumorales Circulantes (CTCs): potenciales biomarcadores en Carcinoma Hepatocelular

IP: Beatriz Minguez Rosique
Collaborators: Itxarone Izaskun Bilbao Aguirre, Elena Vargas Accarino, Maria Teresa Salcedo Allende, Monica Higuera Urbano
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI21/00714
Duration: 01/01/2022 - 31/12/2025

Implementation and new biomarker development for Personalised Medicine for Childhood Cancers in Spain

IP: Lucas Moreno Martín-Retortillo
Collaborators: Aroa Soriano Fernández, Miguel Segura Ginard, Lorena Valero Arrese, Raquel Hladun Alvaro, Elena Antima Martinez Saez, Marta Sese Faustino, Gabriela Guillén Burrieza, Josep Roma Castanyer, Andrea Vilaplana Blanes, Estela Carrasco López, Margarita Ortega Blanco, Implementation and new biomarker development for Personalised Medicine for Childhood Cancers in Spain, Asbleidy Carolina Torres Barbosa, Berta Campos Estela
Funding agency: Instituto de Salud Carlos III
Funding: 369260
Reference: PMP21/00073
Duration: 01/01/2022 - 31/12/2025

Blog

News

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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