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Translational Molecular Pathology

Our group aims to unravel the molecular mechanisms of cancer progression and metastasis to identify new diagnostic, prognostic and therapeutic targets in cancer. By combining the knowledge and availability of human tumors in the Pathology department with the expertise of the basic molecular cell biology research group, we focus on:

  • Understanding: the molecular mechanisms underlying clonal cooperation and intercellular communication in heterogeneous tumors.
  • The role of MNK kinases in cellular stress resistance.
  • The role of ITGB3 in intercellular communication via extracellular vesicles in cancer metastasis (Santiago Ramon y Cajal).
  • The role of direct cell-cell communication via gap junctions and intercellular protrusions in cancer (Trond Aasen)
  • The malignant transition of Plexiform Neurofibromas (Cleofe Romagosa).

Projects

INtegrative GENomic, digital Imaging and clinical information towars Precision Oncology Optimization – INGENIO

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Josep Tabernero Caturla, Jordi Temprana Salvador, INtegrative GENomic, digital Imaging and clinical information towars Precision Oncology Optimization – INGENIO, Ana Mazaltob Oaknin benzaquen, Josep Castellví Vives, Ana Vivancos Prellezo, Raquel Pérez López, Joaquim Mateo Valderrama, Javier Hernandez Losa, Vicente Peg Camara, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 80400
Reference: PMP21/00107
Duration: 01/01/2022 - 30/06/2026

ESTUDIO DEL PAPEL DE LA CENTRALIZACIÓN DEL DIAGNÓSTICO ANATOMOPATOLÓGICO Y LA APLICACIÓN DE ESTRATÉGIAS DE MEDICINA DE PRECISIÓN EN SARCOMAS

IP: Cleofé Romagosa Pérez-Portabell
Collaborators: Xavier Martínez Gómez, Ximena Garcia Torres
Funding agency: Asociación Española Contra el Cáncer
Funding: 270130
Reference: ECAEC222952DEAL
Duration: 01/12/2022 - 30/11/2027

Proyecto colaborativo europeo-latinoamericano y caribeño sobre medicina personalizada para el estudio de trastornos neurológicos

IP: Maria Mar Hernandez Guillamon
Collaborators: Anna Penalba Morenilla, Jessica Camacho Soriano, Anas Chaachou Charradi, Elena Antima Martinez Saez, Laia Fernandez Resano
Funding agency: Instituto de Salud Carlos III
Funding: 174845
Reference: AC22/00051
Duration: 01/01/2023 - 30/06/2026

Hacia un manejo clínico personalizado de pacientes oncológicos con fracaso renal agudo asociado a los immune-checkpoint inhibitors (ICIs)

IP: Maria Jose Soler Romeo
Collaborators: Alejandra Gabaldon Dominguez, Sara Nuñez Delgado, Oriol Bestard Matamoros, Sheila Bermejo Garcia, Concepció Jacobs Cachá, Elena Isabel Crespo Gimeno
Funding agency: Instituto de Salud Carlos III
Funding: 246840
Reference: AC22_00029
Duration: 01/01/2023 - 30/06/2026

Blog

News

The ten groups within the Cancer Area combine basic, translational and clinical research to identify new targets, biomarkers and therapeutic strategies

The grants promote new therapeutic strategies and diagnostic tools in highly complex tumors such as glioblastoma, triple-negative breast cancer, and endometrial cancer.

The Department of Health of the Generalitat de Catalunya grants subsidies for carrying out validation tests on innovative projects in the field of health that are in the early stages of development.

Rates

Check the current rates for the services offered by the Translational Molecular Pathology research group.

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Current Rates

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Rates Anatomia Patologica VHIR 2021

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