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Ensayo abierto de seguridad y tolerabilidad a largo plazo de nintedanib oral, añadido al tratamiento estándar, durante al menos 2 años, en niños y adolescentes con Enfermedad Pulmonar Intersticial fibrosante clínicamente significativa (InPedILD™-ON)

  • Protocol code: 1199-0378
  • EudraCT code: 2020-005554-23
  • Pathology: Enfermedad Pulmonar Intersticial
  • Pharmac: Nintedanib
  • Promoter: Boehringer Ingelheim España, S.A
  • Principal investigator:  Moreno Galdó, Antonio
  • Research group:  Creixement i desenvolupament
  • Service: Al·lergologia i Pneumologia pediàtrica
  • Phase: Fase III
  • Recruiting: Closed
  • Status: Cerrado

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
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Estudio de fase II abierto y multicéntrico para evaluar la seguridad, farmacocinética y eficacia de Nedosiran en pacientes pediátricos desde el nacimiento hasta los 5 años de edad con hiperoxaluria primaria y función renal relativamente intacta

  • Protocol code: DCR-PHXC-203
  • EudraCT code: 2021-001083-16
  • Pathology: Hiperoxaluria Primaria
  • Pharmac: Nedosiran
  • Promoter: Dicerna Pharmaceuticals
  • Principal investigator:  Ariceta Iraola, Gema
  • Research group:  Fisiopatologia renal
  • Service: Nefrologia Pediàtrica
  • Phase: Fase II
  • Recruiting: Closed
  • Status: Cerrado

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Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
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Estudio de continuación abierto para evaluar la seguridad y eficacia a largo plazode la solución inyectable DCR-PHXC (uso subcutáneo) en pacientes conhiperoxaluria primaria

  • Protocol code: DCR-PHXC-301
  • EudraCT code: 2018-003099-10
  • Pathology: Primary Hyperoxaluria
  • Pharmac: DCR PHXC Solution for Injection (subcutaneous use)
  • Promoter: Dicerna Pharmaceuticals
  • Principal investigator:  Ariceta Iraola, Gema
  • Research group:  Kidney Physiopathology
  • Service: Pediatric Nephrology
  • Phase: Phase II
  • Recruiting: Open
  • Status: Activo

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Estudio aleatorizado, con enmascaramiento doble y comparativo con un placebo, en el que se evalúa galcanezumab en pacientes adolescentes de entre 12 y 17 años con migraña crónica - Estudio REBUILD-2

  • Protocol code: I5Q-MC-CGAT
  • EudraCT code: 2018-004622-28
  • Pathology: Migraña
  • Pharmac: Galcanezumab
  • Promoter: Eli Lilly
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Cefalea i dolor neurològic
  • Service: Neurologia
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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Estudio aleatorizado, con enmascaramiento doble y comparativo con un placebo,en el que se evalúa galcanezumab en pacientes de entre 6 y 17 años con migrañaepisódica - Estudio REBUILD-1

  • Protocol code: I5Q-MC-CGAS
  • EudraCT code: 2017-004351-23
  • Pathology: Migraña
  • Pharmac: Galcanezumab
  • Promoter: Eli Lilly
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Headache and Neurological Pain
  • Service: Neurology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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Estudio prospectivo, aleatorizado, abierto, multicéntrico para evaluar los beneficios y riesgos de la conversión de receptores adolescentes de aloinjerto renal existente desde 12 años hasta menos de 18 años de edad a un régimen inmunosupresor con Belatacept en comparación con la continuación con un régimen con un inhibidor de la calcineurina y su cumplimiento con las medicaciones inmunosupresoras

  • Protocol code: IM103-402
  • EudraCT code: 2018-000237-12
  • Pathology: Adolescent Renal Allografts
  • Pharmac: Belatacept-based Immunosuppressive Regimen
  • Promoter: Bristol-Myers Squibb
  • Principal investigator:  Ariceta Iraola, Gema
  • Research group:  Kidney Physiopathology
  • Service: Pediatric Nephrology
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Cerrado

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Estudio en fase II abierto para evaluar la seguridad y eficacia de DCR-PHXC en pacientes con Hiperoxaluria primaria tipo 1 o 2 e insuficiencia renal grave con o sin diálisis

  • Protocol code: DCR-PHXC-204
  • EudraCT code: 2020-002826-97
  • Pathology: Primary Hyperoxaluria
  • Pharmac: DCR-PHXC
  • Promoter: Dicerna Pharmaceuticals
  • Principal investigator:  Ariceta Iraola, Gema
  • Research group:  Kidney Physiopathology
  • Service: Pediatric Nephrology
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Finalizado

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Ensayo clínico de viabilidad de la combinación de AloCelyvir con quimioterapia y radioterapia para el tratamiento de niños y adolescentes con tumores sólidos extra-craneales en recaída o refractarios.

  • Protocol code: FIBHNJ-2019-01
  • EudraCT code: 2019-001154-26
  • Pathology: Relapsed or refractory extracranial solid tumors in children and adolescents
  • Pharmac: AloCelyvir with chemotherapy and radiotherapy
  • Promoter: FUNDACIÓN DE INVESTIGACIÓN BIOMÉDICA DEL HOSPITAL INFANTIL UNIVERSITARIO NIÑO JESÚS
  • Principal investigator:  Moreno Martín-Retortillo, Lucas
  • Research group:  Càncer i malalties hematològiques infantils
  • Service: Oncohematologia Pediàtrica
  • Phase: Fase I
  • Recruiting: Open
  • Status: Activo

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Estudio en Fase 3, de 12 meses de tratamiento abierto con Lasmiditan en pacientes pediátricos con migraña

  • Protocol code: H8H-MC-LAHW
  • EudraCT code: 2019-004379-38
  • Pathology: Migraña
  • Pharmac: Lasmiditan
  • Promoter: Eli Lilly
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Headache and Neurological Pain
  • Service: Neurology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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Opciones para el alivio de la migraña en pediatría: Estudio aleatorizado, doble ciego de Lasmiditan frente a placebo para tratar el episodio agudo de migraña..

  • Protocol code: H8H-MC-LAHV
  • EudraCT code: 2019-004378-24
  • Pathology: Migraña
  • Pharmac: Lasmiditan
  • Promoter: Eli Lilly
  • Principal investigator:  Pozo Rosich, Patricia
  • Research group:  Headache and Neurological Pain
  • Service: Neurology
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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Estudio de fase III para evaluar la seguridad y la eficacia de PF-06939926en el tratamiento de la distrofia muscular de Duchenne (CIFFREO)

  • Protocol code: C3391003
  • EudraCT code: 2019-002921-31
  • Pathology: Distrofia muscular de Duchenne
  • Pharmac: PF-06939926
  • Promoter: Pfizer
  • Principal investigator:  Munell Casadesus, Francina
  • Research group:  Neurologia infantil
  • Service: Neurologia pediàtrica
  • Phase: Phase III
  • Recruiting: Closed
  • Status: Finalizado

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Estudio doble ciego, aleatorizado y controlado con placebo para evaluar la eficacia y la seguridad de odevixibat (A4250) en niños con atresia biliar que se han sometido a hepatoportoenterostomía de Kasai (BOLD)

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Escalating Dose and Randomized, Controlled Study of Nusinersen (BIIB058) in Participants With Spinal Muscular Atrophy

  • Protocol code: 232SM203
  • EudraCT code: 2019-002663-10
  • Pathology: Atrofia muscular espinal
  • Pharmac: Nusinersen (BIIB058)
  • Promoter: Biogen
  • Principal investigator:  Munell Casadesus, Francina
  • Research group:  Neurologia infantil
  • Service: Neurologia pediàtrica
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Cerrado

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Estudio de fase 1 en el que se evalúa LY3295668 (un inhibidor de lacinasa Aurora A) en monoterapia y en politerapia en pacientes con neuroblastomarecidivante o resistente al tratamiento.

  • Protocol code: J1O-MC-JZHD
  • EudraCT code: 2019-001042-18
  • Pathology: Neuroblastoma
  • Pharmac: Aurora Kinase A Inhibitor LY3295668 erbumine
  • Promoter: Eli Lilly
  • Principal investigator:  Moreno Martín-Retortillo, Lucas
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Phase I
  • Recruiting: Closed
  • Status: Finalizado

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Estudio de fase II, aleatorizado, abierto y multicéntrico para evaluar la reactogenicidad, seguridad e inmunogenicidad de la vacuna pediátrica candidata de subunidades de herpes zóster (PED-HZ/su) de GSK tras su administración intramuscular con una pauta de dos dosis a niños inmunodeprimidos receptores de trasplante renal de 1-17 años de edad.

  • Protocol code: ZOSTER-47 (200075)
  • EudraCT code: 2019-000607-33
  • Pathology: Herpes zóster en sujetos inmunodeprimidos
  • Pharmac: subunit candidate vaccine (PED-HZ/su)
  • Promoter: GlaxoSmithKline
  • Principal investigator:  Martínez Gómez, Xavier
  • Research group:  Epidemologia i salut pública
  • Service: Medicina Preventiva
  • Phase: Phase II
  • Recruiting: Open
  • Status: Activo

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Estudio de fase 1/2 del inhibidor de RET oral LOXO 292 en pacientes pediátricos con tumores sólidos avanzados o tumores primarios del sistema nervioso central ambos con alteración de RET.

  • Protocol code: LOXO-RET-18036 (292036) J2G-OX-JZJJ
  • EudraCT code: 2019-000212-28
  • Pathology: Tumores sólidos o primarios del sistema nervioso central con alteración avanzada de RET
  • Pharmac: Oral RET Inhibitor LOXO-292
  • Promoter: Eli Lilly
  • Principal investigator:  Hladun Alvaro, Raquel
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Phase I
  • Recruiting: Closed
  • Status: Finalizado

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A Phase 2 Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With Thymidine Kinase 2 Deficiency (TK2)

  • Protocol code: MT-1621-102
  • EudraCT code: 2018-004277-27
  • Pathology: Deficiencia de timidina quinasa 2
  • Pharmac: Combination pyrimidine nucleos(t)ides
  • Promoter: UCB Biosciences Inc. (United States)
  • Principal investigator:  Munell Casadesus, Francina
  • Research group:  Neurologia infantil
  • Service: Neurologia pediàtrica
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Finalizado

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Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Estudio global, multicéntrico, abierto, comparativo con controles históricos equiparables, de SHP611 intratecal en sujetos con leucodistrofia metacromática infantil tardía

  • Protocol code: SHP611-201
  • EudraCT code: 2018-003291-12
  • Pathology: Leucodistrofia metacromática tardía
  • Pharmac: Intrathecal SHP611
  • Promoter: Takeda
  • Principal investigator:  Del Toro Riera, Mireia
  • Research group:  Neurologia infantil
  • Service: Neurologia pediàtrica
  • Phase: Phase II
  • Recruiting: Closed
  • Status: Finalizado

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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Estudio abierto, de seguridad a largo plazo, de tolerabilidad y de eficacia de GIVINOSTAT en todos los pacientes con DMD que hayan sido tratadospreviamente en uno de los estudios de GIVINOSTAT.

  • Protocol code: DSC/14/2357/51
  • EudraCT code: 2017-000397-10
  • Pathology: Distrofia muscular de Duchenne
  • Pharmac: GIVINOSTAT
  • Promoter: ITALFARMACO
  • Principal investigator:  Munell Casadesus, Francina
  • Research group:  Neurologia infantil
  • Service: Neurologia pediàtrica
  • Phase: Phase III
  • Recruiting: Open
  • Status: Activo

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I have read and accept the data protection policy *.
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Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.

Seguimiento a largo plazo (LTFU) de pacientes tratados con la terapia celularCART dirigida a CD19 basada en vectores lentivirales

  • Protocol code: CCTL019A2205B
  • EudraCT code: 2014-001673-14
  • Pathology: Patologías del sistema immunitario. Seguimiento a largo plazo de pacientes expuestos a la terapia lentiviral con células CAR-T
  • Pharmac: Lentiviral-Based CD19 directed CAR T-Cell Therapy
  • Promoter: Novartis
  • Principal investigator:  Díaz de Heredia Rubio, Maria Cristina
  • Research group:  Childhood Cancer and Blood Disorders
  • Service: Pediatric Oncohematology
  • Phase: Phase II
  • Recruiting: Open
  • Status: Activo

Contact Form

I have read and accept the data protection policy *.
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This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Controller: Fundació Hospital Universitari Vall Hebron Institut de Recerca – VHIR- G60594009.
Purpose: Request for information on VHIR clinical research.
Legitimation: Your consent. The data requested is necessary and your request cannot be processed if you do not provide them.
Transfers: Your data will not be transferred to third parties except to the Principal Investigator who leads the research in order to be able to respond to your query.
Data retention time: As long as they are useful for the purpose for which they were collected and responsibilities may arise.
Rights: You can access, rectify, delete your data, oppose or limit its processing and request its portability, as well as revoke your consent without retroactive effects by contacting lopd@vhir.org. The revocation of consent and the opposition to the processing of your data will prevent the purpose from being carried out. DPO: dpd@ticsalutsocial.org. More information 
The request for information on a research project or clinical trial does not entail inclusion in it.