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Ana Maria Gonzalez Castro

I am a postdoctoral researcher at the Neuro-Immune-Gastroenterology Research Group. My interest is focused on improving the understanding of the role of immune cells (mast cells, eosinophils and plasma cells) askey playeres in the control of intestinal mucosal barrier mechanisms in patients with Irritable Bowel Syndrome and Microscopic Colitis.

Institutions of which they are part

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
Vall Hebron Institut de Recerca

Ana Maria Gonzalez Castro

Institutions of which they are part

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
Vall Hebron Institut de Recerca

I am a postdoctoral researcher at the Neuro-Immune-Gastroenterology Research Group. My interest is focused on improving the understanding of the role of immune cells (mast cells, eosinophils and plasma cells) askey playeres in the control of intestinal mucosal barrier mechanisms in patients with Irritable Bowel Syndrome and Microscopic Colitis.

I graduated in Biology from the Faculty of Biology of the Autonomous University of Barcelona in 1999 and completed my doctoral thesis in Digestive Pathophysiology (University of Barcelona, 2006). I then joined the laboratory of the Digestive System Service of the Hospital Vall d'Hebron under the supervision of Dr. Xavier Molero in the Pathophysiology and Treatment of Pancreatic Diseases group. From 2009 to 2011, I worked as a postdoctoral researcher in the Neuro-Immuno-Gastroenterology group led by Dr Javier Santos, VHIR, where together with Dr. María Vicario I focused on the study of immune cell populations, with particular attention to the role of mast cells and plasma cells in the pathophysiology of irritable bowel syndrome. In 2011 I received a postdoctoral research fellowship from Linkoping University (Sweden). My research there focused on studying the humoral immune response in the colonic mucosa of patients with ulcerative colitis and the effect of stress on the colonic mucosa of healthy volunteers. In 2013, I joined the group of Mucosal Translational Immunology as a post-doctoral researcher, together with Dr María Vicario. My research has been aimed at improving the current understanding of the pathophysiological mechanisms underlying gastrointestinal disorders and identifying immune changes in the intestinal mucosa that are associated with altered intestinal permeability and the development of intestinal inflammation. I am currently a postdoctoral researcher in the Neuro-Immuno-Gastroenterology Laboratory led by Dr Santos, collaborating with the principal investigators on varius research projects and coordinating the research work in the laboratory. I also participate in the training of undergraduate, masters and pre-doctoral students and I am very committed to the training of young researchers.. Since 2022, I have been a professor in the Master in Translational Biomedical Research (VHIR-UAB).

Projects

Identificación de un panel integrado de biomarcadores no invasivos predictivos del diagnóstico de colitis microscópica

IP: Danila Guagnozzi
Collaborators: Beatriz Lobo Alvarez, Ana Maria Gonzalez Castro, Lara Aguilera Castro, Marc Pigrau Pastor, Stefania Landolfi
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI17/01443
Duration: 01/01/2018 - 30/06/2022

Validación e implementación de un panel molecular para el diagnóstico positivo del síndrome del intestino irritable con diarrea y para el diagnóstico diferencial de la diarrea crónica

IP: Fco Javier Santos Vicente
Collaborators: Ana Maria Gonzalez Castro, Lara Aguilera Castro, Marc Pigrau Pastor, Cristina Martínez Martínez, Adoración Nieto Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 220220
Reference: PI17/01902
Duration: 01/01/2018 - 30/06/2022

Identificación de perfiles bacterianos y epigenéticos género-dependientes en la fisiopatogenia del síndrome de intestino irritable.

IP: Carmen Alonso Cotoner
Collaborators: Ana Maria Gonzalez Castro, Adoración Nieto Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 128865
Reference: PI15/00301
Duration: 01/01/2016 - 30/11/2020

Desarrollo de un panel diagnóstico innovador para el Síndrome del Intestino Irritable basado en la expresión sistémica diferencial de miRNAs, asociado a manifestaciones clínicas y a patología intestinal

IP: Fco Javier Santos Vicente
Collaborators: Ana Maria Gonzalez Castro, Cristina Martínez Martínez
Funding agency: Instituto de Salud Carlos III
Funding: 171215
Reference: PI14/00994
Duration: 01/01/2015 - 30/04/2018

Related news

Among the genes described, there are some related to digestive system functions, which reinforces the biological entity of irritable bowel syndrome as a digestive disease.

The international study, in which Vall d'Hebron participated, monitored patients who were hospitalized for COVID-19 for 12 months and compared their gastrointestinal symptoms with another group of patients diagnosed with other medical pathologies.

Els estudis avançaran en els camps de les malalties digestives, el VIH, la fatiga crònica, les patologies cardíaques, l’hepatitis, la diabetis i l’oftalmologia.

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