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Ana Maria Gonzalez Castro

I am a postdoctoral researcher at the Neuro-Immune-Gastroenterology Research Group. My interest is focused on improving the understanding of the role of immune cells (mast cells, eosinophils and plasma cells) askey playeres in the control of intestinal mucosal barrier mechanisms in patients with Irritable Bowel Syndrome and Microscopic Colitis.

Institutions of which they are part

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
Vall Hebron Institut de Recerca

Ana Maria Gonzalez Castro

Institutions of which they are part

Postdoctoral researcher
Physiology and Pathophysiology of the Digestive Tract
Vall Hebron Institut de Recerca

I am a postdoctoral researcher at the Neuro-Immune-Gastroenterology Research Group. My interest is focused on improving the understanding of the role of immune cells (mast cells, eosinophils and plasma cells) askey playeres in the control of intestinal mucosal barrier mechanisms in patients with Irritable Bowel Syndrome and Microscopic Colitis.

I graduated in Biology from the Faculty of Biology of the Autonomous University of Barcelona in 1999 and completed my doctoral thesis in Digestive Pathophysiology (University of Barcelona, 2006). I then joined the laboratory of the Digestive System Service of the Hospital Vall d'Hebron under the supervision of Dr. Xavier Molero in the Pathophysiology and Treatment of Pancreatic Diseases group. From 2009 to 2011, I worked as a postdoctoral researcher in the Neuro-Immuno-Gastroenterology group led by Dr Javier Santos, VHIR, where together with Dr. María Vicario I focused on the study of immune cell populations, with particular attention to the role of mast cells and plasma cells in the pathophysiology of irritable bowel syndrome. In 2011 I received a postdoctoral research fellowship from Linkoping University (Sweden). My research there focused on studying the humoral immune response in the colonic mucosa of patients with ulcerative colitis and the effect of stress on the colonic mucosa of healthy volunteers. In 2013, I joined the group of Mucosal Translational Immunology as a post-doctoral researcher, together with Dr María Vicario. My research has been aimed at improving the current understanding of the pathophysiological mechanisms underlying gastrointestinal disorders and identifying immune changes in the intestinal mucosa that are associated with altered intestinal permeability and the development of intestinal inflammation. I am currently a postdoctoral researcher in the Neuro-Immuno-Gastroenterology Laboratory led by Dr Santos, collaborating with the principal investigators on varius research projects and coordinating the research work in the laboratory. I also participate in the training of undergraduate, masters and pre-doctoral students and I am very committed to the training of young researchers.. Since 2022, I have been a professor in the Master in Translational Biomedical Research (VHIR-UAB).

Projects

Contribución diferencial del epitelio intestinal a la fisiopatología de la diarrea crónica en el síndrome del intestino irritable y la colitis microscópica. Perfil clínico-biológico para el diagnóstico diferencial.

IP: -
Collaborators: Beatriz Lobo Alvarez, Merce Albert Bayo, Inés de Torres Ramirez, Natalia Rodriguez Santas, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Xavier Serra Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 183920
Reference: PI19/01643
Duration: 01/01/2020 - 30/06/2024

Development, dIagnostic and prevention of gender-related Somatic and mental COmorbitiEs in IRritable bowel syndrome In Europe (DISCOvERIE)

IP: Fco Javier Santos Vicente
Collaborators: Beatriz Lobo Alvarez, José Alegre Martin, Amanda Rodríguez Urrutia, Silvia Muñoz Caller, Carmen Alonso Cotoner, Jesus Castro Marrero, Natalia Rodriguez Santas, Ana Maria Gonzalez Castro, Marc Pigrau Pastor, Adoración Nieto Ruiz, Natalia Llonga Tejedor, Alejandro Henao Paez, Consuelo Cammarota
Funding agency: EUROPEAN COMMISSION
Funding: 1148684.84
Reference: DISCOVERIE_H2020-SC1-BHC_2019
Duration: 01/01/2020 - 31/05/2025

Identificación de un panel integrado de biomarcadores no invasivos predictivos del diagnóstico de colitis microscópica

IP: Danila Guagnozzi
Collaborators: Beatriz Lobo Alvarez, Ana Maria Gonzalez Castro, Lara Aguilera Castro, Marc Pigrau Pastor, Stefania Landolfi
Funding agency: Instituto de Salud Carlos III
Funding: 159720
Reference: PI17/01443
Duration: 01/01/2018 - 30/06/2022

Validación e implementación de un panel molecular para el diagnóstico positivo del síndrome del intestino irritable con diarrea y para el diagnóstico diferencial de la diarrea crónica

IP: Fco Javier Santos Vicente
Collaborators: Ana Maria Gonzalez Castro, Lara Aguilera Castro, Marc Pigrau Pastor, Cristina Martínez Martínez, Adoración Nieto Ruiz
Funding agency: Instituto de Salud Carlos III
Funding: 220220
Reference: PI17/01902
Duration: 01/01/2018 - 30/06/2022

Related news

Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

The European project DISCOvERIE, led by Vall d’Hebron, paves the way for more personalized diagnoses and new treatment strategies to improve patients’ quality of life.

15 researchers from the Rheumatology, Systemic Diseases and the Physiology and Pathophysiology of the Digestive Tract groups gave around 25 presentations.

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