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Carmen Pilar Simeón i Aznar

Institutions of which they are part

Main researcher
Systemic Diseases
Vall Hebron Institut de Recerca

Carmen Pilar Simeón i Aznar

Institutions of which they are part

Main researcher
Systemic Diseases
Vall Hebron Institut de Recerca

Research lines

Genetic basis of scleroderma.

With this study we aim at studying the genetic background of the disease to deepen in its pathogenesis to be able to establish links between genetic variations and different clinic-biologic patterns. This research is based on a multicentric study and it is led by Prof. Javier Martín from the "Instituto López-Neyra" of Parasitology, CSIC (Granada). We contribute to it by sending samples from our cohort of patients along with the clinical data.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Spanish Registry of Scleroderma patients (Systemic Autoimmune Diseases Group, Spanish Internal Medicine Association).

This multicentric study includes 14 hospitals with a cohort of 916 scleroderma patients. Its main goal consists in determining both the prognosis factors and the survival of these patients.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Significance of Capillaroscopy in Raynaud's phenomenon and scleroderma.

We want to describe the capillaroscopy alterations observed in patients with Raynaud's phenomenon and scleroderma. Our main objective is to establish the different patterns that may be related to visceral involvement and to the prognosis in the early stages of the disease.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Protein expression of small collagenase 3 and leucine-rich proteoglycans in cutaneous tissue of patients with diffuse scleroderma.

This study, carried out along with researchers from the Hospital del Mar and from the "Institut Municipal d'Investigació Mèdica", aims at correlating the expression of SLRPs and MMP-13 with the severity of cutaneous involvement, hand dysfunctional capacity, capillaroscopy patterns, and cutaneous ultrasonography of patients affected with diffuse scleroderma in different evolutive stages of the disease.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Projects

EUSTAR PROJECT 2023

IP: Carmen Pilar Simeón i Aznar
Collaborators: -
Funding agency: European Scleroderma Trials and Research group
Funding: 20000
Reference: EUSTAR/GRANT/2023/SIMEON
Duration: 01/05/2024

Ajuts Grups de Recerca (SGR) 2022

IP: Jaume Alijotas Reig
Collaborators: Moisés Labrador Horrillo, Carmen Pilar Simeón i Aznar, Anna Sala Cunill, Roser Solans Laque, Segundo Bujan Rivas, Mar Guilarte Clavero, Vicenç Fonollosa Pla, Fernando Martínez Valle, Victòria Cardona Dahl, Francesc Miro Mur, Alfredo Guillen Del Castillo, Albert Selva O'Callaghan, José Pardos Gea, Laura Donaire Lancharro, Ariadna Anunciacion Llunell
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00048
Duration: 01/01/2022 - 30/06/2025

Estudio de expresión de antígenos en tejido tumoral de pacientes con Esclerosis Sistémica.

IP: Alfredo Guillen Del Castillo
Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/01804
Duration: 01/01/2023 - 31/12/2025

Design of an integrative patients stratification approach for the systemic sclerosis management

IP: Carmen Pilar Simeón i Aznar
Collaborators: -
Funding agency: Fundació La Marató de TV3
Funding: 72250
Reference: 202022-30-31-32-33
Duration: 10/05/2021 - 31/12/2024

Related news

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.

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