Carmen Pilar Simeón i Aznar Institutions of which they are part Main researcher Systemic Diseases Vall Hebron Institut de Recerca Email Carmen Pilar Simeón i Aznar Email Institutions of which they are part Main researcher Systemic Diseases Vall Hebron Institut de Recerca
Research lines Protein expression of small collagenase 3 and leucine-rich proteoglycans in cutaneous tissue of patients with diffuse scleroderma. This study, carried out along with researchers from the Hospital del Mar and from the "Institut Municipal d'Investigació Mèdica", aims at correlating the expression of SLRPs and MMP-13 with the severity of cutaneous involvement, hand dysfunctional capacity, capillaroscopy patterns, and cutaneous ultrasonography of patients affected with diffuse scleroderma in different evolutive stages of the disease. IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla Evaluation and characterization of cardiac involvement in patients with Systemic Sclerosis. Cardiac involvement is one of the most serious internal organ involvements and the leading cause of death in SSc patients. The prevalence is 14% by clinical observation and even higher by autopsy Many SSc patients with cardiac involvement are asymptomatic or underdiagnosed. The condition may progress silently to overt clinical manifestations, including systolic and/or diastolic dysfunction, myocardial ischaemia, myocardial hypertrophy, heart failure, pericardial effusion and arrhythmias. Early detection of cardiac abnormalities is therefore very important. We evaluate cardiac involvement by echocardiography, MR, SPECT, and coronary CT. IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla Specific Antinuclear antibodies of scleroderma as markers for different clinical patterns. We want to establish the relationship between the presence of specific autoantibodies for scleroderma (anti-centromere, anti-topoisomerase 1, anti-polymerase III, anti-U3 RNP, Anti-Th/To, Anti-Pm/Scl, anti-Ku) with the different demographic and clinical features as well as with the disease prognosis. IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla Genetic basis of scleroderma. With this study we aim at studying the genetic background of the disease to deepen in its pathogenesis to be able to establish links between genetic variations and different clinic-biologic patterns. This research is based on a multicentric study and it is led by Prof. Javier Martín from the "Instituto López-Neyra" of Parasitology, CSIC (Granada). We contribute to it by sending samples from our cohort of patients along with the clinical data. IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla Pagination Current page 1 Page 2 Next page › Last page » Projects Ajuts Grups de Recerca (SGR) 2022 IP: Jaume Alijotas Reig Collaborators: Moisés Labrador Horrillo, Carmen Pilar Simeón i Aznar, Anna Sala Cunill, Roser Solans Laque, Segundo Bujan Rivas, Mar Guilarte Clavero, Vicenç Fonollosa Pla, Fernando Martínez Valle, Victòria Cardona Dahl, Francesc Miro Mur, Alfredo Guillen Del Castillo, Albert Selva O'Callaghan, José Pardos Gea, Laura Donaire Lancharro, Ariadna Anunciacion Llunell Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 0.01 Reference: 2021 SGR 00048 Duration: 01/01/2022 - 30/06/2025 Estudio de expresión de antígenos en tejido tumoral de pacientes con Esclerosis Sistémica. IP: Alfredo Guillen Del Castillo Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero Funding agency: Instituto de Salud Carlos III Funding: 75020 Reference: PI22/01804 Duration: 01/01/2023 - 31/12/2025 Design of an integrative patients stratification approach for the systemic sclerosis management IP: Carmen Pilar Simeón i Aznar Collaborators: - Funding agency: Fundació La Marató de TV3 Funding: 72250 Reference: 202022-30-31-32-33 Duration: 10/05/2021 - 09/05/2024 ESTUDIO DE NUEVOS ANTIGENOS EN ESCLERODERMIA IP: Carmen Pilar Simeón i Aznar Collaborators: Vicenç Fonollosa Pla, Ana María Marín Sánchez, Alfredo Guillen Del Castillo Funding agency: Instituto de Salud Carlos III Funding: 78650 Reference: PI16/02088 Duration: 01/01/2017 - 30/06/2021 Pagination Current page 1 Page 2 Next page › Last page »
