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Chaysavanh Manichanh

Institutions of which they are part

Head of group
Microbiome Research
Vall Hebron Institut de Recerca

Research lines

The Human Microbiome

The Microbiome Research Group seeks to investigate the role of the microbiota in health and disease. Its secondary objectives include: 1. Role of the microbiota in health and disease 2. Tools to characterize the microbiome structure and function 3. Micro-biomarkers for diagnosis and prognosis 4. Fecal microbiota transplantation as a therapeutic strategy 5. Impact of diet on the gut microbial ecosystem

IP: Chaysavanh Manichanh

Gut Microbiota

The human microbiome is the collective genomes of all microorganisms living at the multiple sites of the human body (oral cavity, skin, nasal cavity, gastrointestinal tract (GI) and vagina). Human (Homo sapiens) and their commensal microorganisms have evolved together over the last 200,000 years and have become dependent on one another. Interaction between humans and their symbiotic bacteria is essential to many aspects of normal ‘mammalian’ physiology, ranging from metabolic activity to immune homeostasis, and ecological or genetic changes that disturb this mutualism can result in disease. It reflects the evolutionary selection pressures acting at both the levels of the host and the microbial cells and has a direct profound impact on human health. This line of research aims at understanding the role of the gut microbiome in intestinal disorders using ‘omics approaches. Our research group proposes a service-collaboration in Microbiome analysis. You can find further information on our prices at the following URL.

IP: Chaysavanh Manichanh

Projects

Evaluate the effect of diet on the gut microbial community

IP: Chaysavanh Manichanh
Collaborators: Zaida Soler Luque
Funding agency: Instituto de Salud Carlos III
Funding: 119567
Reference: FI21/00262
Duration: 01/01/2022 - 31/12/2025

Inflammatory Bowel Disease and Microbiome: Diagnosis and prediction of disease activity from the lab to the patients

IP: Chaysavanh Manichanh
Collaborators: Luis Fernando Mayorga Ayala
Funding agency: Instituto de Salud Carlos III
Funding: 65000
Reference: CM21/00198
Duration: 01/01/2022 - 31/12/2023

Inflammatory Bowel Disease and Microbiome: Diagnosis and prediction of disease activity from the lab to the patients

IP: Chaysavanh Manichanh
Collaborators: Claudia Maria Herrera de Guise, Natalia Borruel Sainz, Francesc Casellas Jordá, Encarna Varela Castro, Luis Fernando Mayorga Ayala, Francisca Yañez Araya, Zixuan Xie
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI20/00130
Duration: 01/01/2021 - 31/12/2023

Deciphering the fungus-host-microbiota interplay to improve the management of fungal infections (FunHoMic)

IP: Chaysavanh Manichanh
Collaborators: Zixuan Xie
Funding agency: EUROPEAN COMMISSION
Funding: 236504.88
Reference: FUNHOMIC_H2020MSCA-ITN2018
Duration: 01/01/2019 - 31/12/2022

Related news

La composició de la microbiota intestinal és única, com ho són les nostres empremtes dactilars.

The quantification of the gut microbiota, combined with clinical data, would be useful to facilitate the correct diagnosis of patients and offer them the appropriate treatment for their pathology and also to prevent the appearance of flares.

FunHoMic integrates experts in fungal pathogenesis, immunology, microbial ecology and "omics" technologies to train 13 researchers to identify biomarkers related to the risk of infection by fungi such as Candida.

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