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Diana Fernandes de Rafael

I possess a Master in Pharmaceutical Sciences (2010) granted by the Faculty of Pharmacy from the Lisbon University, and a PhD degree in Pharmaceutical Technology (2017) from the same University. During my PhD I had the opportunity to do research stays at Ludwig Maximillian University (LMU), Munich, Bellvitge Biomedical Research Institute (IDIBELL) and Vall D'Hebron Research Institute (VHIR), Barcelona. Actually, I am a post-doctoral researcher at Drug Delivery and Targeting Group, VHIR working in the field of nanotechnology-based drug delivery systems applied to several diseases.

Institutions of which they are part

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Vall Hebron Institut de Recerca

Diana Fernandes de Rafael

Institutions of which they are part

Main researcher
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Vall Hebron Institut de Recerca

I possess a Master in Pharmaceutical Sciences (2010) granted by the Faculty of Pharmacy from the Lisbon University, and a PhD degree in Pharmaceutical Technology (2017) from the same University. During my PhD I had the opportunity to do research stays at Ludwig Maximillian University (LMU), Munich, Bellvitge Biomedical Research Institute (IDIBELL) and Vall D'Hebron Research Institute (VHIR), Barcelona. Actually, I am a post-doctoral researcher at Drug Delivery and Targeting Group, VHIR working in the field of nanotechnology-based drug delivery systems applied to several diseases.

Being a multidisciplinary scientist, during 10 years of research career I acquired expertise in different areas of knowledge such as Pharmaceutical Technology, Nanomedicine, Chemistry, Molecular Biology, Cancer Signalling Pathways, Preclinical Validation, etc. My board knowledge in the field of biomedical sciences granted by my training as pharmacist and my research experience, allowed me to have a comprehensive and integrative view of the different stages of drug development from the bench to the bedside. My career has been fully dedicated to the design, development, and preclinical validation of innovative delivery systems for a wide range of challenging diseases with a special attention to oncology.
My active participation at different international projects (12) and collaborations with a variety of research groups have resulted in the authorship of several publications in high impact peer-reviewed journals (35 publications, 15 as corresponding/first author, h-index 18). Also, she is co-inventor of two patents about delivery systems for gene delivery and the creation of cell penetrating peptides. Moreover, I am truly active in science dissemination both to share the knowhow with the pairs at international conferences, and also in citizenship dissemination actions. Additionally, due to her experience in the fields of Pharmaceutical Technology and Molecular Biology, I am giving classes at the Master of Molecular Biotechnology from the University of Barcelona. Most importantly, I was responsible for the supervision of the thesis of different pre-graduated, master and PhD students (14).

Projects

iMM-CARE: BOOSTING CLINICAL RESEARCH FOR THE BENEFIT OF SOCIETY

IP: Begoña Benito Villabriga
Collaborators: Rafael José Navajo Garrido, Elvira Sepulveda Duran, Shirley Guzmán Avilés, Shirley Guzmán Avilés, Isabel Novoa Garcia, Isabel Novoa Garcia, Francisco González Romero, Francisco González Romero, Anna Santamaria Margalef, Joaquim Calbó Angrill, Alba Jané Dern, Alba Jané Dern, Sara Mas Assens, Estefania De la Torre Villaescusa, Iván García Cerdá, Iván García Cerdá, Sara Badenas Leyva, Mireia Pares Oliva, Victor Royo Calavera, Victor Royo Calavera, Marta Vallvé Òdena, Marta Vallvé Òdena, Sheyla Pascual Martín, VHIR VHIR , Diana Fernandes de Rafael
Funding agency: EUROPEAN COMMISSION
Funding: 2000000
Reference: IMM-CARE_HE_WIDERA-2022
Duration: 01/05/2023 - 30/04/2029

NanoDIRE-CT - Uso de nanobodies para terapia dirigida contra células madre tumorales

IP: -
Collaborators: Simon Schwartz Navarro, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Diana Fernandes de Rafael
Funding agency: Ministerio Ciencia, Innovación y Universidades
Funding: 322172.61
Reference: RTC2019-006809-1
Duration: 01/09/2020 - 31/12/2023

Ministerio de Ciencia

BIODEGRADABLE NANOPARTICLES OF SIMVASTATIN AS NEW THERAPEUTIC TOOL FOR CHRONIC LIVER DISEASE (NANOSIM)

IP: Joan Genescà Ferrer
Collaborators: Diana Fernandes de Rafael
Funding agency: Instituto de Salud Carlos III
Funding: 199946.45
Reference: AC18/00033
Duration: 01/01/2019 - 31/12/2022

Desenvolupament de noves nanopartícules funcionals dirigides al nòdul limfàtic per a l'eliminació del reservori latent de VIH

IP: María José Buzón Gómez
Collaborators: Juan Lorente Guerrero, Laura García Latorre, Jordi Temprana Salvador, Joaquin Seras Franzoso, Simon Schwartz Navarro, Jordi Navarro Mercadé, Sandra Mancilla Zamora, Zamira Vanessa Diaz Riascos, Judit Grau Exposito, Meritxell Genesca Ferrer, Diana Fernandes de Rafael
Funding agency: Fundació La Marató de TV3
Funding: 199998.75
Reference: 20180510
Duration: 10/05/2019 - 31/12/2022

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