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Ibane Abasolo Olaortua

I am a researcher, head of the Drug Delivery & Targeting (DDT) group and a member of the Clinical Biochemistry Service. Our research is aimed at improving the treatment of various diseases through the use of nanoparticles of natural or synthetic origin that selectively deliver treatments to the cells that need them. I am also a member of the Department of Biochemistry and Molecular Biology of the Autonomous University of Barcelona and I participate in the VHIR Master's Degree in Translational Biomedicine where I coordinate the internship module.

Institutions of which they are part

Head of group
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Vall Hebron Institut de Recerca
Biologist
Bioquímica
Cross-departmental services

Ibane Abasolo Olaortua

Institutions of which they are part

Head of group
Clinical Biochemistry, Drug Delivery & Therapy (CB-DDT)
Vall Hebron Institut de Recerca
Biologist
Bioquímica
Cross-departmental services

I am a researcher, head of the Drug Delivery & Targeting (DDT) group and a member of the Clinical Biochemistry Service. Our research is aimed at improving the treatment of various diseases through the use of nanoparticles of natural or synthetic origin that selectively deliver treatments to the cells that need them. I am also a member of the Department of Biochemistry and Molecular Biology of the Autonomous University of Barcelona and I participate in the VHIR Master's Degree in Translational Biomedicine where I coordinate the internship module.

I graduated in Biochemistry and Biology at the University of Navarra. During my doctorate in the laboratories of Dr. Alfonso Calvo (CIMA, Pamplona) and Prof. Zhou Wang (Northwestern University, Chicago, USA), I studied the role of a peptide hormone, adrenomedullin, in cancer. Later, I continued my postdoctoral training in the group of Prof. F.X. Real (IMIM, Barcelona), where I acquired extensive experience in experimental mouse models, from the generation of transgenic models to their molecular characterization, an experience that I completed with a specialization in molecular imaging techniques at the IAT-PRBB.
Since 2007, I have been working at Vall d'Hebron, where I started as a post-doctoral researcher and head of the technology platform called Functional Validation & Preclinical Research (FVPR)-U20 ICTS. Since 2021 I am also the leader of the Drug Delivery & Targeting group at VHIR and at the CIBER for Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN).
My research, and that of my group, seeks to improve the treatment of different diseases through the use of nanoparticles and hydrogels. These systems are specifically designed to protect the therapeutic agent and cause it to be released where and when it is needed. Noteworthy, we work at all steps of the preclinical development, from the design of the nanomaterial, to its synthesis, characterization and testing in experimental models of the disease.
I am currently leading two European projects (SafeNMT and Mimic-key) and two Spanish projects (PI21/00930 and NanoDireCT), focused on the treatment of cancer (breast, pancreas and prostate) and lysosomal storage diseases (Fabry, Sanfilippo and pycnodysostosis).

Research lines

Obtenció i us de vesícules extracel·lulars com vehicles per proteïnes i biomolècules

IP: Ibane Abasolo Olaortua

Projects

Personal Técnico de Apoyo 2021

IP: Ibane Abasolo Olaortua
Collaborators: Diana Fernandes de Rafael, Miriam Izquierdo Sans
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 42600
Reference: PTA2021-021005-I
Duration: 01/01/2023 - 31/12/2023

Ministerio de Ciencia

EVERETT: Engineered mesenchymal stromal cell Extracellular Vesicles for immunomodulatory biotherapy and Enzyme REplacemenT Therapy

IP: Ibane Abasolo Olaortua
Collaborators: -
Funding agency: Agence Nationale de la Recherche
Funding: 0.01
Reference: EVERETT_ANR-BIOPNSE2020
Duration: 01/11/2022 - 31/10/2025

EXOPROD - Vesículas extracelulares dirigidas, como sistemas de liberación de proteínas recombinantes

IP: Ibane Abasolo Olaortua
Collaborators: -
Funding agency: Fundación Innov. y Prosp. Salud en España - FIPSE
Funding: 30000
Reference: 3969-21
Duration: 07/04/2021 - 07/12/2021

Mejora del tratamiento de las enfermedades de depósito lisosomal mediante vehículos nanométricos optimizados

IP: Ibane Abasolo Olaortua
Collaborators: Marc Miquel Moltó Abad, Miriam Izquierdo Sans
Funding agency: Generalitat de Catalunya - Departament de Salut
Funding: 90306.55
Reference: SLT017/20/000181
Duration: 05/07/2021 - 31/12/2024

Related news

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

During the last year, the collaboration between Vall d’Hebron and ZeClinics has found three nanobody candidates with potent anticancer properties in zebrafish model.

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