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Javier Hernandez Losa

Institutions of which they are part

Main researcher
Translational Molecular Pathology
Vall Hebron Institut de Recerca

Javier Hernandez Losa

Institutions of which they are part

Main researcher
Translational Molecular Pathology
Vall Hebron Institut de Recerca

Research lines

Role of HER3 expression in carcinogenesis of endometrial and breast tumors. Search for new predictive markers to anti-HER treatments.

The cell signaling pathways downstream of epidermal growth factor receptor family members is tightly regulated in normal epithelial cells, and its alteration induce different cell processes (cell proliferation, cell growth, etc...) which triggers in cellular transformation. Within this family receptors, HER1/EGFR and HER2/neu are the best known, being subject to interest other family members like HER3. The aim of the study is establish de role of HER3 protein expression by Immunohistochemistry in endometrial and breast tumors, and establish any association with clinic-pathological parameters. Furthermore, we would like to know the implication of HER3 in the resistance mechanisms to anti-HER treatment agents.

IP: Javier Hernandez Losa

Projects

INtegrative GENomic, digital Imaging and clinical information towars Precision Oncology Optimization – INGENIO

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Jordi Temprana Salvador, Josep Castellví Vives, Joaquim Mateo Valderrama, Javier Hernandez Losa, Vicente Peg Camara, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 80400
Reference: PMP21/00107
Duration: 01/01/2022 - 31/12/2025

Patologia molecular translacional

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Cleofé Romagosa Pérez-Portabell, Maria Rosa Somoza Lopez de Haro, Jordi Temprana Salvador, Teresa Moline Marimon, Jessica Camacho Soriano, Carmela Iglesias i Felip, Josep Castellví Vives, Elena Muro Blanc, Marta Cano Galietero, Elena Antima Martinez Saez, Javier Hernandez Losa, Marta Sese Faustino, Vicente Peg Camara, Irene Sansano Valero, Trond Aasen , Patologia molecular translacional, Stefan Hummer , Milena Marcela Riaño Rodriguez
Funding agency: AGAUR no fer servir-correcte 4301-37
Funding: 40000
Reference: 2021 SGR 01138
Duration: 01/01/2022 - 31/12/2024

Anatomia Patològica (GRC)

IP: -
Collaborators: Cleofé Romagosa Pérez-Portabell, Inés de Torres Ramirez, Angel García Jiménez, Josep Castellví Vives, Maria Teresa Salcedo Allende, Javier Hernandez Losa, Marta Sese Faustino, Vicente Peg Camara, Irene Sansano Valero, Stefania Landolfi , Trond Aasen
Funding agency: AGAUR no fer servir-correcte 4301-37
Funding:
Reference: 2014 SGR 1131
Duration: 01/01/2014 - 31/12/2016

Red Temática de Investigación Cooperativa en Cáncer (RTICC)

IP: -
Collaborators: Cleofé Romagosa Pérez-Portabell, Maria Rosa Somoza Lopez de Haro, Angel García Jiménez, Teresa Moline Marimon, Josep Castellví Vives, Pere Barba Suñol, Javier Hernandez Losa, Marta Sese Faustino, Vicente Peg Camara, Stefania Landolfi , Trond Aasen
Funding agency: Instituto de Salud Carlos III
Funding: 209700
Reference: RD12/0036/0057
Duration: 01/01/2013 - 30/06/2017

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