Javier Hernandez Losa

Institutions of which they are part

Predoctoral researcher
Translational Molecular Pathology

Vall Hebron Institut de Recerca

Institutions of which they are part

Predoctoral researcher
Translational Molecular Pathology

Vall Hebron Institut de Recerca

Research lines

Role of HER3 expression in carcinogenesis of endometrial and breast tumors. Search for new predictive markers to anti-HER treatments.

The cell signaling pathways downstream of epidermal growth factor receptor family members is tightly regulated in normal epithelial cells, and its alteration induce different cell processes (cell proliferation, cell growth, etc...) which triggers in cellular transformation. Within this family receptors, HER1/EGFR and HER2/neu are the best known, being subject to interest other family members like HER3. The aim of the study is establish de role of HER3 protein expression by Immunohistochemistry in endometrial and breast tumors, and establish any association with clinic-pathological parameters. Furthermore, we would like to know the implication of HER3 in the resistance mechanisms to anti-HER treatment agents.

IP: Javier Hernandez Losa

Projects

inhibición de la comunicación celular para la prevención del desarrollo de metástasis y la resistencia a terapias antitumorales. Desarrollo de dos nuevas aproximaciones terapéuticas

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Maria Rosa Somoza Lopez de Haro, Josep Castellví Vives, Sara Garcia Ortega, Elena Muro Blanc, Marta Cano Galietero, Javier Hernandez Losa, Marta Sese Faustino, Stefan Hummer, Lourdes Elena Salazar Huayna, Lourdes Elena Salazar Huayna
Funding agency: Instituto de Salud Carlos III
Funding: 240000
Reference: PI23/01754
Duration: 01/01/2024 - 31/12/2026

INtegrative GENomic, digital Imaging and clinical information towars Precision Oncology Optimization – INGENIO

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Jordi Temprana Salvador, Josep Castellví Vives, Joaquim Mateo Valderrama, Javier Hernandez Losa, Vicente Peg Camara, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 80400
Reference: PMP21/00107
Duration: 01/01/2022 - 31/12/2025

Patologia molecular translacional

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Cleofé Romagosa Pérez-Portabell, Maria Rosa Somoza Lopez de Haro, Jordi Temprana Salvador, Teresa Moline Marimon, Jessica Camacho Soriano, Carmela Iglesias i Felip, Josep Castellví Vives, Elena Muro Blanc, Marta Cano Galietero, Elena Antima Martinez Saez, Javier Hernandez Losa, Marta Sese Faustino, Vicente Peg Camara, Irene Sansano Valero, Trond Aasen, Stefan Hummer
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 40000
Reference: 2021 SGR 01138
Duration: 01/01/2022 - 30/06/2025

Anatomia Patològica (GRC)

IP: Santiago Ramon y Cajal Agüeras
Collaborators: Cleofé Romagosa Pérez-Portabell, Inés de Torres Ramirez, Angel García Jiménez, Josep Castellví Vives, Maria Teresa Salcedo Allende, Javier Hernandez Losa, Marta Sese Faustino, Vicente Peg Camara, Irene Sansano Valero, Stefania Landolfi , Trond Aasen
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding:
Reference: 2014 SGR 1131
Duration: 01/01/2014 - 31/12/2016