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Laura Ludovica Gramegna

Laura Ludovica Gramegna, MD, neuroradiologist and principal investigator of the Stroke Research Group. My work integrates translational neuroscience, interventional neuroradiology, and advanced neuroimaging. I lead multidisciplinary projects translating molecular knowledge of cerebral vascular malformations into innovative treatments. I coordinate clinical trials in interventional neuroradiology and develop MRI- and CT-based biomarkers for ischaemic and haemorrhagic vascular diseases.

Institutions of which they are part

Postdoctoral researcher
Stroke research
Vall Hebron Institut de Recerca

Laura Ludovica Gramegna

Institutions of which they are part

Postdoctoral researcher
Stroke research
Vall Hebron Institut de Recerca

Laura Ludovica Gramegna, MD, neuroradiologist and principal investigator of the Stroke Research Group. My work integrates translational neuroscience, interventional neuroradiology, and advanced neuroimaging. I lead multidisciplinary projects translating molecular knowledge of cerebral vascular malformations into innovative treatments. I coordinate clinical trials in interventional neuroradiology and develop MRI- and CT-based biomarkers for ischaemic and haemorrhagic vascular diseases.

I graduated in medicine in 2012, specialised in neuroradiology in 2017, and obtained a PhD in Neuroscience in 2023.
As a lecturer at the University of Bologna, I combined teaching, clinical practice, and research. I have expertise in neurological disease pathophysiology, genetics, and advanced neuroimaging biomarkers, and trained at University Medical Center Hamburg-Eppendorf (UKE). I have also trained in design thinking to address complex problems through empathy, creativity, and experimentation.
I collaborate with VHIR groups, particularly the Interventional Neuroradiology Research Team led by Dr Alejandro Tomasello, and with Barcelona institutions, including IRSJD, ICN2, the University of Barcelona, and Hospital del Mar. I also participate in international projects with the University of Bologna and the university hospitals of Oxford and Cambridge.
I currently coordinate three research projects funded through public-private partnerships, including CaixaResearch Health, and co-supervise doctoral theses and master's dissertations. I am the author or co-author of 68 high-impact publications and have an h-index of 20.
My research focuses on innovative, minimally invasive therapies for cerebral arteriovenous malformations, the glymphatic system in dural fistulas, and clinical trials on cerebral aneurysms. I also advance neuroradiological image analysis to develop clinically applicable biomarkers for vascular and neurodegenerative diseases.
My main scientific contribution is a multidisciplinary, translational approach that integrates diverse perspectives to address complex clinical challenges, including molecular treatments for cerebral arteriovenous malformations.

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Funding has been obtained for 43 projects under the calls for Health R&D&I Projects, Health Technology Development, and Independent Clinical Research

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