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Marisol Ruiz Meana

I have a degree in Veterinary Medicine and a Master's degree in Biochemistry from the Autonomous University of Barcelona. I obtained my PhD at the VHIR Cardiovascular Diseases’ group under the supervisión of Prof. David Garcia-Dorado on the mechanisms of cell death during myocardial ischemia-reperfusion. I am currently Principal Investigator of the group and since 2019 I have assumed the coordination of the laboratory. I’m a professor of the Master's Degree in Translational Biomedical Research at VHIR and have supervised 5 doctoral theses in the last years. I have an H index of 42.

Institutions of which they are part

Main researcher
Cardiovascular Diseases
Vall Hebron Institut de Recerca

Marisol Ruiz Meana

Institutions of which they are part

Main researcher
Cardiovascular Diseases
Vall Hebron Institut de Recerca

I have a degree in Veterinary Medicine and a Master's degree in Biochemistry from the Autonomous University of Barcelona. I obtained my PhD at the VHIR Cardiovascular Diseases’ group under the supervisión of Prof. David Garcia-Dorado on the mechanisms of cell death during myocardial ischemia-reperfusion. I am currently Principal Investigator of the group and since 2019 I have assumed the coordination of the laboratory. I’m a professor of the Master's Degree in Translational Biomedical Research at VHIR and have supervised 5 doctoral theses in the last years. I have an H index of 42.

I have been dedicated to cardiovascular research since 1993, when I began my doctoral thesis under the direction of Dr. Garcia-Dorado, in the laboratory of Cardiovascular Diseases of the Vall d'Hebron Hospital. I completed my training with an international stay in the physiology laboratory of Prof. Hans Michael Piper, at the University of Dusseldorf, which allowed me to learn the model of isolated adult cardiomyocytes (we were pioneers in our country), one of the fundamental pillars of our research, and become familiar with (ratio)fluorescence imaging techniques for real-time quantification of intracellular ionic changes in cardiomyocytes. Since then, I have specialized in studies of cell biology and mitochondrial pathophysiology within the field of cardioprotection, mainly in the context of myocardial infarction. In recent years I have focused my interest on research into the mechanisms of aging and its impact on cardiomyocyte dysfunction, alterations in the interorganelle communication between the sarcoplasmic reticulum and mitochondria, and the accumulation of advanced glycation products as triggers of cell senescence.
Our research group, integrated within the Cardiology Service directed by Dr. Ignacio Ferreira, has been recognized as a Consolidated Research Group by the Generalitat of Catalonia and belongs to the Spanish network CIBER-CV. I am currently Principal Investigator of two projects on cardiovascular aging financed by the Instituto de Salud Carlos III and the Spanish Society of Cardiology, and I’m the vice-chair of a COST action financed by the European Union that brings together researchers from more than 35 countries with a common scientific interest in heart failure (EU-COST METAHEART).
My teaching activity includes the training of postgraduate students as a professor and coordinator of the Cardiovascular Diseases module of the Master in Translational Biomedical Research at the VHIR, and the training of doctoral students. I have been a member of the Internal Scientific Committee of my institution since 2018.

Projects

Modulación de la función mitocondrial y señalización de la cardiopatía endógena por canales mitocondriales de Conexina 43

IP: -
Collaborators: José Antonio Barrabés Riu, Antonio Rodríguez Sinovas, Ignasi Barba Vert, Jordi Bañeras Rius, Elisabet Miro Casas, Marisol Ruiz Meana, Mireia Andres Villarreal, Javier Inserte Igual
Funding agency: Ministerio de Ciencia e Innovación-MICINN
Funding: 665500
Reference: SAF2008-03067
Duration: 01/01/2009 - 31/12/2014

Ministerio de Ciencia

Patologia Cardiocirculatòria

IP: -
Collaborators: Ignacio Ferreira González, José Antonio Barrabés Riu, Antonia Sambola Ayala, Nuria Rivas Gandara, Angeles Rojas Lopez, Antonio Rodríguez Sinovas, Joan Castell Conesa, Patologia Cardiocirculatòria, Elsa Nieto Santa, Josep Pinar Sopena, Teresa González Alujas, Enric Domingo Ribas, Jaume Sagristà Sauleda, Aida Ribera Sole, Patologia Cardiocirculatòria, Rosa María Lidón Corbi, Gerard Marti Aguasca, Imanol Otaegui Irurueta, Ignasi Barba Vert, Bruno García del Blanco, Pilar Tornos Mas, Elisabet Miro Casas, Marisol Ruiz Meana, Javier Inserte Igual
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 56160
Reference: 2009 SGR 802
Duration: 01/01/2010 - 30/04/2014

Conexina43 mitocondrial en cardiomiocitos y su participación en la respuesta celular durante la isquemia-reperfusión

IP: Marisol Ruiz Meana
Collaborators: Antonio Rodríguez Sinovas
Funding agency: -Sociedad Española de Cardiologia
Funding: 15025
Reference: SEC_02_2006
Duration: 01/01/2006 - 31/12/2006

Determinación del papel de la hipercontracción y la apertura del poro de transición mitocondrial como efectores de la muerte celular de cardiomiocitos durante la reperfusión miocárdica

IP: Marisol Ruiz Meana
Collaborators: Angeles Rojas Lopez, Ignasi Barba Vert
Funding agency: Instituto de Salud Carlos III
Funding: 32065
Reference: PI060996
Duration: 01/01/2007 - 30/12/2009

Related news

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.

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