Màrius Aguirre Canyadell Institutions of which they are part Senior researcher Musculoskeletal Tissue Engineering Vall Hebron Institut de Recerca Email Màrius Aguirre Canyadell Email Institutions of which they are part Senior researcher Musculoskeletal Tissue Engineering Vall Hebron Institut de Recerca
Research lines Bone formation Research on bone regeneration in diseases such as bone necrosis of the femoral head, bone lengthening or bone reconstruction after tumour resection surgery. We work in revascularization, growth factors and cell therapy. We have developed several animal models of injury on which we are applying different therapies. IP: Màrius Aguirre Canyadell Bone Regeneration This research line seeks to promote bone regeneration using advanced cell therapy. Our alliance between biologists, engineers and clinical researchers enables us to develop new tissue engineering products that after thorough evaluation in the scopes of basic research and preclinical testing can then be applied in the human clinical setting. Current Studies: 1. Autologous cell therapy with adult stem cells for osteonecrosis of the femoral head. Osteonecrosis Clinical phase I-II study: We are currently conducting a comparative study between a product developed by our research group of advanced cell therapy in the context of osteonecrosis of the femoral head precollapse stage. It is a pioneering study at a national and international level by assessing the bone regenerative capability of this product compared to the classical treatment of core decompression. 2. Treatment of femoral head osteonecrosis with advanced cell therapy and biomaterials in an experimental sheep model. Osteonecrosis preclinical study: We are evaluating mesenchymal stem cells expanded ex-vivo associated with different scaffolds and BMP in osteonecrosis of the femoral head in an ovine model. We are evaluating the different osteoconductive, osteoinductive and osteogenerative components to optimize the best biologic for the treatment of femoral head necrosis. 3. Experimental study of "in vivo" expanded adult stem cell therapy . Critical size defect preclinical study: We are evaluating mesenchymal stem cells expanded ex-vivo in a critical segmental defect in an ovine model. IP: Màrius Aguirre Canyadell, Roberto Vélez Villa Projects ACTUALIZACIÓN DE EQUIPAMIENTOS DE ALTA TECNOLOGIA PARA LA PLATAFORMA DE IMAGEN PRECLINICA. ADQUISICION DE UN EQUIPO DE ULTRASONIDOS DE INVESTIGACION PRECLINICA IP: Inmaculada Fuentes Camps Collaborators: Diego Arango Corro, Anna Meseguer Navarro, Antonio Rodríguez Sinovas, Francesc Bosch Albareda, Victor Franco Puntes, José Raul Herance Camacho, Jordi Giralt López de Sagred, Màrius Aguirre Canyadell, Xavier Serres Créixams, Simon Schwartz Navarro, Joaquim Mateo Valderrama, Mario Marotta Baleriola, Anna Rosell Novel, Joan Genescà Ferrer Funding agency: Ministerio de Ciencia e Innovación-MICINN Funding: 108390 Reference: EQC2019-006322-P Duration: 01/01/2019 - 31/12/2020 TRASLACIÓN DE UN PRODUCTO DE INGENIERÍA TISULAR ALOGÉNICO CON MSC DE GELATINA DE WHARTON PARA EL TRATAMIENTO DE LA OSTEONECROSIS EN PACIENTES ONCOLÓGICOS PEDIÁTRICOS. IP: Joaquim Vives Armengol Collaborators: Roberto Vélez Villa, Nayana Joshi Jubert, Lluis Martorell Cedres, Maria Cristina Díaz de Heredia Rubio, Màrius Aguirre Canyadell, Irene Portas Torres, Raquel Cabrera Perez Funding agency: Instituto de Salud Carlos III Funding: 87120 Reference: PI19/01788 Duration: 01/01/2020 - 30/06/2024 Femoral head osteonecrosis treatment with advanced cell therapy and biomaterials in an experimental sheep animal model. IP: Màrius Aguirre Canyadell Collaborators: Roberto Vélez Villa, Joaquim Vives Armengol, Anna Server Salvà Funding agency: Fundació La Marató de TV3 Funding: 200000 Reference: 122030 Duration: 30/01/2013 - 31/12/2016 Estudio experimental de terapia celular con células madre adultas expandida "in vivo" IP: Màrius Aguirre Canyadell Collaborators: Joaquim Piqueras Pardellans, Joaquim Vives Armengol Funding agency: Instituto de Salud Carlos III Funding: 79255 Reference: PI11/02231 Duration: 01/01/2012 - 30/06/2016 Pagination Current page 1 Page 2 Page 3 Next page › Last page »
