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Ricardo Pujol Borrell

Sóc metge, combino el treball clínic i el de laboratori i faig per ajudar a aquells malalts en els quals sistema immunitari genera malalties complexes, a vegades difícils de diagnosticar. Per això em recolzo en els meus col·legues del laboratori d'immunologia i en pediatres, pneumòlegs i digestòlegs, i en algun moment, en gairebé tots els serveis de l'hospital.

Institutions of which they are part

Main researcher
Translational Immunology
Vall Hebron Institut de Recerca
Doctor
Immunology
Cross-departmental services

Ricardo Pujol Borrell

Institutions of which they are part

Main researcher
Translational Immunology
Vall Hebron Institut de Recerca
Doctor
Immunology
Cross-departmental services

Sóc metge, combino el treball clínic i el de laboratori i faig per ajudar a aquells malalts en els quals sistema immunitari genera malalties complexes, a vegades difícils de diagnosticar. Per això em recolzo en els meus col·legues del laboratori d'immunologia i en pediatres, pneumòlegs i digestòlegs, i en algun moment, en gairebé tots els serveis de l'hospital.

Per la meva edat, la meva trajectòria és llarga, amb dues especialitats i dos doctorats. El meu entusiasme per la recerca m'ha portat a realitzar molts projectes i publicacions i càrrecs de gestió de la recerca. En aquest moment m'agrada veure com els beneficis de la immunoteràpia es van estenent de les immunodeficiències a les malalties reumatològiques i al càncer. Dia a dia des del laboratori i la consulta veig com el diagnòstic de les immunodeficiències millora gràcies a les proves genètiques i els tractaments ja no es redueixen a l'administració d'immunoglobulines ja que fàrmacs i teràpies cel·lulars i genètiques van començant a ser una realitat. I en el cas de les malalties on se centra la meva investigació immunodeficiències i autoimmunitat endocrina, les perspectives també milloren i els nostres projecte contribueixen a l'esforç internacional.

Research lines

Immune tolerance and autoimmune disease

1.1  Analysis of central tolerance (thymic) to thyrotropin receptor in Graves' disease.

1.2  Biomarkers of therapeutic response to in Graves' disease

1.3. Explore the use of system biology tools for the identification of new biomarkers in autoimmune diseases


This line is being developed in collaboration with the Endocrinology and Pediatric Heart Surgery groups of HUVH and also with Endocrinology group of Hospital Universitari Germans Trias i Pujol.

IP: Ricardo Pujol Borrell, Roger Colobran Oriol

Genetics and immunological factors in COViD-19

Determinants of severity in COVID-19 are still poorly understood but are suspected to be predominantly host factors. Besides age, sex and previous comorbidities, we investigate two other general host factors:


1-Genetic variants causing life-threatening COVID-19: We are mostly focused in genetics of immune system. This research line is under the COVIDHGE consortium.


2-The state of the immune system seems to be an important factor but the immunotypes of risk have not yet been clearly defined. The aim of this line of research is to identify the immune mechanisms that determine the severity of SARS-CoV-2 infection in order to propose and validate biomarkers of prognosis and therapeutic requirements.

IP: Ricardo Pujol Borrell, Manuel Hernández González, Roger Colobran Oriol, Romina Dieli Crimi, Mónica Martínez Gallo

Projects

COVID-19, PERFIL INMUNOLÓGICO DE RIESGO

IP: Ricardo Pujol Borrell
Collaborators: Manuel Hernández González, Mónica Martínez Gallo, Moisés Labrador Horrillo, Gema Codina Grau, Albert Blanco Grau, Andres Antón Pagarolas, Antonio Álvarez Fernandez, Nuria Fernández Hidalgo, Roser Ferrer Costa, Esteve Ribera Pascuet, Juan Carlos Ruiz Rodriguez, Jaume Ferrer Sancho, Anna Suy Franch, Pere Soler Palacín, Albert Selva O'Callaghan, Tomàs Pumarola Suñé, Isabel Ruiz Camps, Marta Miarons Font, Daniel Alvarez De la Sierra, Andrea Martín Nalda, Eva Polverino, Romina Dieli Crimi, Romina Dieli Crimi
Funding agency: Instituto de Salud Carlos III
Funding: 229000
Reference: COV20/00416
Duration: 08/05/2020 - 08/11/2021

RECEPTORES INHBITORIOS (NEGATIVE IMMUNE CHECKPOINT RECEPTORS, NCRs) EN AUTOINMUNIDAD TIROIDEA Y CANCER, NUEVAS VÍAS TERAPÉUTICAS EN AUTOINMUNIDAD

IP: Ricardo Pujol Borrell
Collaborators: Oscar González López, Roser Ferrer Costa, Carmela Iglesias i Felip, Ana María Marín Sánchez, Anna Casteras Román, Elena Garralda Cabanas, Daniel Alvarez De la Sierra
Funding agency: Instituto de Salud Carlos III
Funding: 147620
Reference: PI17/00324
Duration: 01/01/2018 - 30/06/2022

Sol·licitud de les beques Predoctorals. Modalitat VHIR-MIR

IP: Ricardo Pujol Borrell
Collaborators: Daniel Alvarez De la Sierra
Funding agency: Fundació Institut de Recerca HUVH
Funding: 46800
Reference: PRED-VHIR-16-34/ALVAREZ
Duration: 22/05/2017 - 21/05/2020

European Network for Translational Immunology Research and Education (ENTIRE): From Immunomonitoring to Personalized Immunotherapy

IP: Ricardo Pujol Borrell
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 1
Reference: ENTIRE_BM0907_COST2010
Duration: 09/06/2010 - 08/06/2014

Related news

The results show that, in some patients with mutations in the X chromosome, the healthy gene is inactivated and the mutated gene manifests itself, which favors the onset of the disease.

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As age increases in men, the concentration of the hormone in the blood drops and this increases the likelihood of severe progression of the infection in COVID-19 patients

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