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Vicenç Fonollosa Pla

Soc Consultor Sènior de Medicina Interna a la Unitat de Malalties Autoimmunes Sistèmiques de l'Hospital Universitari Vall d’Hebron.

Institutions of which they are part

Systemic Diseases
Vall Hebron Institut de Recerca
Internal Medicine
General Hospital

Vicenç Fonollosa Pla

Institutions of which they are part

Systemic Diseases
Vall Hebron Institut de Recerca
Internal Medicine
General Hospital

Soc Consultor Sènior de Medicina Interna a la Unitat de Malalties Autoimmunes Sistèmiques de l'Hospital Universitari Vall d’Hebron.

Formació:

Llicenciat en Medicina i Cirurgia per la Universitat  Autònoma de Barcelona (UAB)  l’any 1975. Doctor en Medicina per la UAB. Especialista en Medicina Interna per l’Hospital Universitari Vall d’Hebron de Barcelona. 

Activitat Assistencial:

Consultor Sènior de Medicina Interna (Unitat de Malalties Autoimmunes Sistèmiques) de l'Hospital Universitari Vall d’Hebron (HVHB) de Barcelona. Ha estat coordinador de la Unitat de Malalties Autoimmunes Sistèmiques a HVHB i responsable del Gabinet de Capil·laroscòpies de HVHB.

 Activitat Docent/Acadèmica:

Catedràtic d’Universitat (Facultat de Medicina-UAB). Degà de la Facultat de Medicina de la UAB. Ha estat Vicedegà de Docència de la Facultat de Medicina (UAB), Coordinador de la Unitat Docent Vall d’Hebron i Director del Departament de Medicina (UAB). Coordinador del 3r curs del Grau de Medicina. Responsable de l’assignatura Fisiopatologia i Semiologia Clínica de tercer curs en el Grau de Medicina i a la UDHVH. Responsable de l’assignatura Medicina i Cirurgia I (Reumatologia i Malalties Autoimmunes Sistèmiques) de 4t curs en el Grau de Medicina i a la UDVHV. Responsable de l’assignatura: Practiques Clíniques Mèdiques de 4t i 5è curs. Responsable de l’assignatura: Pràctiques en Departaments i Serveis Hospitalaris. Responsable de l’assignatura: Bases Biològiques de la Patologia (Grau de Ciències Biomèdiques de la UAB (UDHVH); Director de la Diplomatura: “Actualització diagnòstica i terapèutica de les malalties més prevalents a la comunitat”.

 Activitat investigadora:

L'activitat investigadora s'ha centrat fonamentalment en el marc de les malalties autoimmunes sistèmiques i en particular en la malaltia esclerodèrmica, tant en la seva vessant bàsica com en la clínica. Per al seu desenvolupament s'han obtingut diverses ajudes de caràcter competitiu el que ha generat una notable producció científica. El cos de la recerca pot concretar-se en més de 200 publicacions en revistes indexades, 28 capítols de llibres i 25 tesis dirigides. Coordinador nacional de la Línia de Recerca sobre esclerodèrmia dins del Grup de Malalties Autoimmunes Sistèmiques de la Societat Espanyola de Medicina Interna i Director Científic del Registre Nacional de malalts amb esclerodèrmia (RESCLE).

Research lines

Protein expression of small collagenase 3 and leucine-rich proteoglycans in cutaneous tissue of patients with diffuse scleroderma.

This study, carried out along with researchers from the Hospital del Mar and from the "Institut Municipal d'Investigació Mèdica", aims at correlating the expression of SLRPs and MMP-13 with the severity of cutaneous involvement, hand dysfunctional capacity, capillaroscopy patterns, and cutaneous ultrasonography of patients affected with diffuse scleroderma in different evolutive stages of the disease.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Capillaroscopy abnormalities in primary Sjögren’s syndrome.

We want to describe the capillaroscopy alterations observed in patients with Raynaud's phenomenon and primary Sjögren’s syndrome. Our main objective is to establish if there is a specific capillaroscopic pattern associated with Sjögren syndrome and if it is related to visceral extraglandular involvement.

IP: Roser Solans Laque, Vicenç Fonollosa Pla

Evaluation and characterization of cardiac involvement in patients with Systemic Sclerosis.

Cardiac involvement is one of the most serious internal organ involvements and the leading cause of death in SSc patients. The prevalence is 14% by clinical observation and even higher by autopsy Many SSc patients with cardiac involvement are asymptomatic or underdiagnosed. The condition may progress silently to overt clinical manifestations, including systolic and/or diastolic dysfunction, myocardial ischaemia, myocardial hypertrophy, heart failure, pericardial effusion and arrhythmias. Early detection of cardiac abnormalities is therefore very important. We evaluate cardiac involvement by echocardiography, MR, SPECT, and coronary CT.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Specific Antinuclear antibodies of scleroderma as markers for different clinical patterns.

We want to establish the relationship between the presence of specific autoantibodies for scleroderma (anti-centromere, anti-topoisomerase 1, anti-polymerase III, anti-U3 RNP, Anti-Th/To, Anti-Pm/Scl, anti-Ku) with the different demographic and clinical features as well as with the disease prognosis.

IP: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla

Projects

Ajuts Grups de Recerca (SGR) 2022

IP: Jaume Alijotas Reig
Collaborators: Moisés Labrador Horrillo, Carmen Pilar Simeón i Aznar, Anna Sala Cunill, Roser Solans Laque, Segundo Bujan Rivas, Mar Guilarte Clavero, Vicenç Fonollosa Pla, Fernando Martínez Valle, Victòria Cardona Dahl, Francesc Miro Mur, Alfredo Guillen Del Castillo, Albert Selva O'Callaghan, José Pardos Gea, Laura Donaire Lancharro, Ariadna Anunciacion Llunell
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 0.01
Reference: 2021 SGR 00048
Duration: 01/01/2022 - 30/06/2025

Estudio de expresión de antígenos en tejido tumoral de pacientes con Esclerosis Sistémica.

IP: Alfredo Guillen Del Castillo
Collaborators: Carmen Pilar Simeón i Aznar, Vicenç Fonollosa Pla, Maria Roca Herrera, Janire Perurena Prieto, Irene Sansano Valero
Funding agency: Instituto de Salud Carlos III
Funding: 75020
Reference: PI22/01804
Duration: 01/01/2023 - 31/12/2025

ESTUDIO DE NUEVOS ANTIGENOS EN ESCLERODERMIA

IP: Carmen Pilar Simeón i Aznar
Collaborators: Vicenç Fonollosa Pla, Alfredo Guillen Del Castillo
Funding agency: Instituto de Salud Carlos III
Funding: 78650
Reference: PI16/02088
Duration: 01/01/2017 - 30/06/2021

Autoimmunitat i Malaltia Trombòtica (GRC)

IP: Miguel Vilardell Tarres
Collaborators: Carmen Pilar Simeón i Aznar, Roser Solans Laque, Segundo Bujan Rivas, Vicenç Fonollosa Pla, José Ordi Ros, Josefina Cortes Hernandez, Fernando Martínez Valle, Albert Selva O'Callaghan, Cristina Solé Marce
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding:
Reference: 2014 SGR 329
Duration: 01/01/2014 - 31/12/2016

Related news

The new technology allows more sensitive detection of scleroderma patients' autoantibodies, which are related to the severity and progression of the disease.

Researchers have used an innovative protocol to identify people with this autoimmune disease who have a higher risk of cancer.

It will allow the promotion of research on systemic autoimmune-based diseases that especially affect women of childbearing age and, therefore, can also appear during pregnancy.

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