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Bioengineering, Cell Therapy and Surgery in Congenital Malformations

The research group is composed by clinical researchers (pediatric surgeons, traumatologists, neonatologists and obstetricians) and basic researchers (biochemists, biotechnologists and biologists). Our multidisciplinary team has an extensive expertise in the field of biomedical research and a strong translational spirit to the human clinic. The main objectives of our research are addressed to:

  • The study of the causes and pathophysiology of human congenital malformations.
  • The development of new treatments based on innovative surgical techniques, bioengineering and cell therapy focused on tissue regeneration and addressed to the treatment of these severe pathologies.

In addition, our research team has extensive experience in the field of regenerative medicine and nanomedicine especially focused on the development of new therapeutic strategies for the treatment of musculoskeletal and osteoarticular pathologies and we are currently participating in highly innovative projects both at national and international level.

Publications

Vascularized Ulnar Periosteal Pedicled Flap for Upper Extremity Reconstruction in Adults: A Prospective Case Series of 11 Patients.

PMID: 34016492
Journal: JOURNAL OF HAND SURGERY-AMERICAN VOLUME
Year: 2022
Reference: J Hand Surg Am. 2022 Jan;47(1):86.e1-86.e11. doi: 10.1016/j.jhsa.2021.02.027. Epub 2021 May 18.
Impact factor:
Publication type: Paper in international publication
Authors: Alabau-Rodriguez, Sergi; Barrera-Ochoa, Sergi; Mendez-Sanchez, Gerardo; Mir-Bullo, Xavier; Sapage, Rita; Soldado, Francisco et al.
DOI: 10.1016/j.jhsa.2021.02.027

Impact of the COVID-19 pandemic on patients with paediatric cancer in low-income, middle-income and high-income countries: a multicentre, international, observational cohort study.

PMID: 35410925
Journal: BMJ Open
Year: 2022
Reference: BMJ Open. 2022 Apr 11;12(4):e054690. doi: 10.1136/bmjopen-2021-054690.
Impact factor:
Publication type: Paper in international publication
Authors: Ababneh, Hazim; Abantanga, Francis A; Abbas, Alzhraa Salah; Abdel-Maboud, Mohamed; Abdelhafeez, Hafeez; Abdelsalam, Sherief; Abdelwahab, Mohamed; Abdessamad, El Ouahabi; Abdul Qadir, Muskaan; Abdul-Mumin, Alhassan et al.
DOI: 10.1136/bmjopen-2021-054690

Treatment of hallux valgus in children and adolescents.

PMID: 34871795
Journal: Orthopaedics & Traumatology-Surgery & Research
Year: 2022
Reference: Orthop Traumatol Surg Res. 2022 Feb;108(1S):103168. doi: 10.1016/j.otsr.2021.103168. Epub 2021 Dec 3.
Impact factor: 2.256
Publication type: Review in international publication
Authors: Knorr, Jorge; Soldado, Francisco; Violas, Philippe; Sanchez-Alvarez, Mikel; Domenech, Pedro; de Gauzy, Jerome Sales et al.
DOI: 10.1016/j.otsr.2021.103168

Non-invasive mechanical ventilation in Spanish neonatal units.

PMID: 35786540
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Jun 30. pii: S2341-2879(22)00141-7. doi: 10.1016/j.anpede.2021.08.009.
Impact factor: 1.5
Publication type: Letter whit IF
Authors: Castillo Salinas, Felix; Camba Longueira, Fatima; Montaner Ramon, Alicia; Comunas Gomez, Juan Jose; Fernandez Garcia, Cristina et al.
DOI: 10.1016/j.anpede.2021.08.009

Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions.

PMID: 32229130
Journal: ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA
Year: 2021
Reference: Enferm Infecc Microbiol Clin. 2021 Mar;39(3):134-138. doi: 10.1016/j.eimc.2020.02.015. Epub 2020 Mar 27.
Impact factor: 1.731
Publication type: Paper in national publication
Authors: Melendo, Susana, Fernandez-Polo, Aurora, Castellnou Asens, Ivette, Mendoza-Palomar, Natalia, Barnes-Mayolas, Meritxell, Soler-Palacin, Pere, Soler Palacin, Pere, Melendo Perez, Susana, Mendoza Palomar, Natalia, Nieves Larrosa Escartin, M et al.
DOI: 10.1016/j.eimc.2020.02.015

Arthroscopic Calcaneonavicular Coalition and Too-long Anterior Process of the Calcaneus Resection in Children.

PMID: 33461922
Journal: Journal of Foot & Ankle Surgery
Year: 2021
Reference: J Foot Ankle Surg. 2021 Mar-Apr;60(2):228-232. doi: 10.1053/j.jfas.2019.03.020. Epub 2021 Jan 16.
Impact factor: 1.286
Publication type: Paper in international publication
Authors: Knorr, Jorge, Diaz-Gallardo, Paula, Soldado, Francisco, Domenech, Pedro, Torres-Perez, Ana, Sales de Gauzy, Jerome, Bergua-Domingo, Josep Maria et al.
DOI: 10.1053/j.jfas.2019.03.020

Results of Ovarian Sparing Surgery in Pediatric Patients: Is There a Place for Laparoscopy?

PMID: 32013689
Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques
Year: 2020
Reference: J Laparoendosc Adv Surg Tech A. 2020 Apr;30(4):458-463. doi: 10.1089/lap.2019.0515. Epub 2020 Feb 3.
Impact factor:
Publication type: Paper in international publication
Authors: Guillen, Gabriela; Lopez, Manuel; Lopez-Fernandez, Sergio; Martin-Gimenez, Marta Pilar; Molino, Jose Andres et al.
DOI: 10.1089/lap.2019.0515

Elbow flexion reconstruction with nerve transfer or grafting in patients with brachial plexus injuries: A systematic review and comparison study.

PMID: 30761593
Journal: MICROSURGERY
Year: 2020
Reference: Microsurgery. 2020 Jan;40(1):79-86. doi: 10.1002/micr.30440. Epub 2019 Feb 13.
Impact factor:
Publication type: Review in international publication
Authors: Ayhan, Egemen; Bertelli, Jayme A; Fontecha, Cesar G; Leblebicioglu, Gursel; Soldado, Francisco et al.
DOI: 10.1002/micr.30440

Inter- and Intraobserver Variation in the Assessment of Preoperative Colostograms in Male Anorectal Malformations: An ARM-Net Consortium Survey.

PMID: 33072661
Journal: Frontiers in Pediatrics
Year: 2020
Reference: Front Pediatr. 2020 Sep 18;8:571. doi: 10.3389/fped.2020.00571. eCollection 2020.
Impact factor: 2.634
Publication type: Paper in international publication
Authors: Midrio, Paola, van Rooij, Iris A L M, Brisighelli, Giulia, Garcia, Aracelli, Fanjul, Maria, Broens, Paul, Iacobelli, Barbara D, Gine, Carlos, Lisi, Gabriele, Sloots, Cornelius E J et al.
DOI: 10.3389/fped.2020.00571

Correction to: Analysis of skull bone thickness during growth: an anatomical guide for safe pin placement in halo fixation.

PMID: 32405795
Journal: EUROPEAN SPINE JOURNAL
Year: 2020
Reference: Eur Spine J. 2020 Jul;29(7):1784. doi: 10.1007/s00586-020-06432-5.
Impact factor: 2.458
Publication type: Letter or abstract
Authors: Canavese, F, Knorr, J, Soldado-Carrera, F, Domenech, J, Domenech-Fernandez, P, Yamane, J, Barrios, C et al.
DOI: 10.1007/s00586-020-06432-5

"Non-Touch" Vena Cava Technique as an Improvement in Combined Lung and Liver Procurement in Controlled Donation After Circulatory Death.

PMID: 30655141
Journal: TRANSPLANTATION PROCEEDINGS
Year: 2019
Reference: Transplant Proc. 2019 Jan - Feb;51(1):9-11. doi: 10.1016/j.transproceed.2018.02.216. Epub 2019 Jan 14.
Impact factor: 0.959
Publication type: Paper in international publication
Authors: Sole, J, Caralt, M, Bello, I, Sandiumenge, A, Dopazo, C, Pando, E, Molino, J A, Lazaro, J L, Bilbao, I, Pont, T et al.
DOI: 10.1016/j.transproceed.2018.02.216

Soft-tissue chondroma within the extensor tendon of the index finger in a child.

PMID: 30033358
Journal: Hand surgery & rehabilitation
Year: 2018
Reference: Hand Surg Rehabil. 2018 Oct;37(5):326-327. doi: 10.1016/j.hansur.2018.05.006. Epub 2018 Jul 20.
Impact factor:
Publication type: Other (letters to the editor, abstracts, corrigendum, etc.)
Authors: Barrera-Ochoa, S; Knorr, J; Nunez, J H; Soldado, F et al.
DOI: 10.1016/j.hansur.2018.05.006

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study.

PMID: 29452941
Journal: LANCET INFECTIOUS DISEASES
Year: 2018
Reference: Lancet Infect Dis. 2018 May;18(5):516-525. doi: 10.1016/S1473-3099(18)30101-4. Epub 2018 Feb 13.
Impact factor: 25.148
Publication type: Paper in international publication
Authors: Fergusson, Stuart J, Glasbey, James, Ingabire, Jc Allen, Ismail, Lawani, Salem, Hosni Khairy, Kojo, Anyomih Theophilus Teddy, Lapitan, Marie Carmela, Lilford, Richard, Mihaljevic, Andre L, Morton, Dion et al.
DOI: 10.1016/S1473-3099(18)30101-4

Extravesical Ureteral Reimplantation Following Lich-Gregoir Technique for the Correction of Vesico-Ureteral Reflux Retrospective Comparative Study Open vs. Laparoscopy.

PMID: 30619786
Journal: Frontiers in Pediatrics
Year: 2018
Reference: Front Pediatr. 2018 Dec 18;6:388. doi: 10.3389/fped.2018.00388. eCollection 2018.
Impact factor: 2.335
Publication type: Review in national publication
Authors: Bustangi, Nasir, Kallas Chemaly, Anthony, Scalabre, Aurelien, Khelif, Karim, Luyckx, Stephane, Steyaert, Henri, Varlet, Francois, Lopez, Manuel et al.
DOI: 10.3389/fped.2018.00388

[Is the Mathieu urethroplasty a useful technique for urethrocutaneous fistula repair after hypospadias surgery?]

PMID: 30371029
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2018
Reference: Cir Pediatr. 2018 Oct 17;31(4):176-181.
Impact factor: 0
Publication type: Paper in national publication
Authors: Aguilera-Pujabet, M, Gander, R, Royo, G F, Lopez, M, Asensio, M et al.
DOI:

Kidney transplantation in children weighing 15 kg or less is challenging but associated with good outcome.

PMID: 28359777
Journal: Journal of Pediatric Urology
Year: 2017
Reference: J Pediatr Urol. 2017 Jun;13(3):279.e1-279.e7. doi: 10.1016/j.jpurol.2017.02.025. Epub 2017 Mar 18.
Impact factor: 1.611
Publication type: Editorail in international publication
Authors: Gander, Romy, Asensio, Marino, Royo, Gloria Fatou, Molino, Jose Andres, Ariceta, Gema, Lara, Luis Enrique, Lloret, Josep et al.
DOI: 10.1016/j.jpurol.2017.02.025

Thoracic wall reconstruction with bioabsorbable plates in pediatric malignant thoracic wall tumors.

PMID: 27653461
Journal: JOURNAL OF PEDIATRIC SURGERY
Year: 2017
Reference: J Pediatr Surg. 2017 Mar;52(3):377-381. doi: 10.1016/j.jpedsurg.2016.08.018. Epub 2016 Aug 31.
Impact factor: 1.976
Publication type: Paper in international publication
Authors: Guillen, G, Garcia, L, Marhuenda, C, Pellise, F, Molino, J A, Fontecha, C G, Lopez, S, Lloret, J et al.
DOI: 10.1016/j.jpedsurg.2016.08.018

Treatment of Post-Transplant Lymphocele in Children.

PMID: 28132852
Journal: UROLOGY
Year: 2017
Reference: Urology. 2017 May;103:218-223. doi: 10.1016/j.urology.2016.12.039. Epub 2017 Jan 26.
Impact factor: 2.309
Publication type: Paper in international publication
Authors: Ariceta, Gema, Perez, Mercedes, Coma, Ana, Vilalta, Ramon, Molino, Jose Andres, Gander, Romy, Asensio, Marino, Royo, Gloria Fatou et al.
DOI: 10.1016/j.urology.2016.12.039

[Conservative management of liver trauma and its complications: current gold-standard].

PMID: 27911066
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Jan 25;29(1):19-24.
Impact factor: 0
Publication type: Paper in national publication
Authors: Gander, R, Molino, J A, Santiago, S, Lain, A, Guillen, G, Gine, C, Royo, G, Lopez, S, Perez, M, Diez, I et al.
DOI:

[Gastric tube esophagoplasty using the retroesternal route in children].

PMID: 27911065
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Jan 25;29(1):15-18.
Impact factor: 0
Publication type: Paper in national publication
Authors: Guillen Burrieza, G, Garcia Martinez, L, Molino Gahete, J A, Redecillas Ferreiro, S, Bordon Cabrera, E, Bueno Recio, J, Lloret Roca, J, Lara Valtuena, A, Gine Prades, C et al.
DOI:

[Autologous blood pleurodesis for treatment of spontaneous pneumothorax and persistent air leak in pediatric patients].

PMID: 27911063
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Jan 25;29(1):4-7.
Impact factor: 0
Publication type: Paper in national publication
Authors: Jimenez Arribas, P, Lain Fernandez, A, Guillen Burrieza, G, Lopez-Fernandez, S, Moreno Galdo, A, Lloret Roca, J et al.
DOI:

Two-Port Laparoscopic Descending Colostomy with Separated Stomas for Anorectal Malformations in Newborns.

PMID: 26528853
Journal: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
Year: 2016
Reference: Eur J Pediatr Surg. 2016 Oct;26(5):462-464. doi: 10.1055/s-0035-1566107. Epub 2015 Nov 3.
Impact factor: 1.269
Publication type: Paper in international publication
Authors: Gine, Carlos, Santiago, Saioa, Lara, Alba, Lain, Ana, Lane, Victoria Alison, Wood, Richard J, Levitt, Marc et al.
DOI: 10.1055/s-0035-1566107

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Divuit hores de programa solidari recull més de 8 milions d'euros per lluitar contra les malalties del cor. A Catalunya, una de cada quatre persones moren a causa d'una malaltia del cor o un ictus