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Bioengineering, Cell Therapy and Surgery in Congenital Malformations

The research group is composed by clinical researchers (pediatric surgeons, traumatologists, neonatologists and obstetricians) and basic researchers (biochemists, biotechnologists and biologists). Our multidisciplinary team has an extensive expertise in the field of biomedical research and a strong translational spirit to the human clinic. The main objectives of our research are addressed to:

  • The study of the causes and pathophysiology of human congenital malformations.
  • The development of new treatments based on innovative surgical techniques, bioengineering and cell therapy focused on tissue regeneration and addressed to the treatment of these severe pathologies.

In addition, our research team has extensive experience in the field of regenerative medicine and nanomedicine especially focused on the development of new therapeutic strategies for the treatment of musculoskeletal and osteoarticular pathologies and we are currently participating in highly innovative projects both at national and international level.

Publications

Pediatric kidney retransplantation focused on surgical outcomes.

PMID: 35810139
Journal: Journal of Pediatric Urology
Year: 2022
Reference: J Pediatr Urol. 2022 Jun 25. pii: S1477-5131(22)00288-1. doi: 10.1016/j.jpurol.2022.06.019.
Impact factor: 1.83
Publication type: Paper in international publication
Authors: Gander, Romy; Asensio, Marino; Andres Molino, Jose; Fatou Royo, Gloria; Lopez-Gonzalez, Mercedes; Perez, Victor; Lopez, Manuel; Ariceta, Gema et al.
DOI: 10.1016/j.jpurol.2022.06.019

Analysis of perceived risk and satisfaction with telematic follow-up in patients and families of congenital diaphragmatic hernia patients during SARS-CoV-2 pandemia.

PMID: 35835633
Journal: Journal of healthcare quality research
Year: 2022
Reference: J Healthc Qual Res. 2022 Jun 23. pii: S2603-6479(22)00054-9. doi: 10.1016/j.jhqr.2022.05.009.
Impact factor: 0
Publication type: Paper in international publication
Authors: de Mir, I, Khan, H A, Lopez Fernandez, S, Oliver, B, Rocha, O, Guillen, G, Molino, J A, Iglesias, I, Lopez, M et al.
DOI: 10.1016/j.jhqr.2022.05.009

Page kidney after pediatric kidney transplantation: a case report.

PMID: 35485759
Journal: Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica
Year: 2022
Reference: Cir Pediatr. 2022 Apr 1;35(2):94-98. doi: 10.54847/cp.2022.02.19.
Impact factor: 0
Publication type: Letter or abstract
Authors: Gander, R, Asensio, M, Royo, G F, Lopez, M, Coma, A, Munoz, M, Cruz, A, Rios, H, Ariceta, G, Molino, J A et al.
DOI: 10.54847/cp.2022.02.19

Minimally invasive surgery for pediatric dumbbell neuroblastoma: systematic literature review and report of a single-stage neurosurgical and thoracoscopic approach.

PMID: 34718957
Journal: Clinical & Translational Oncology
Year: 2022
Reference: Clin Transl Oncol. 2022 May;24(5):950-957. doi: 10.1007/s12094-021-02724-4. Epub 2021 Oct 30.
Impact factor: 3.405
Publication type: Review in international publication
Authors: Guillen, G, Hladun, R, Martos, M, Cano, P, Molino, J A, Lopez-Fernandez, S, Lopez, M et al.
DOI: 10.1007/s12094-021-02724-4

Management of COVID-19-Positive Pediatric Patients Undergoing Minimally Invasive Surgical Procedures: Systematic Review and Recommendations of the Board of European Society of Pediatric Endoscopic Surgeons.

PMID: 32550670
Journal: Frontiers in Pediatrics
Year: 2020
Reference: Front Pediatr. 2020 May 7;8:259. doi: 10.3389/fped.2020.00259. eCollection 2020.
Impact factor: 2.634
Publication type: Review in international publication
Authors: Pini Prato, Alessio, Conforti, Andrea, Almstrom, Markus, Van Gemert, Wim, Scuderi, Maria G, Khen-Dunlop, Naziha, Draghici, Isabela, Mendoza-Sagaon, Mario, Gine Prades, Carlos, Chiarenza, Fabio et al.
DOI: 10.3389/fped.2020.00259

Thoracoscopic Bullectomy for Persistent Air Leak in a 14-Year-Old Child with COVID-19 Bilateral Pulmonary Disease.

PMID: 32525726
Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques
Year: 2020
Reference: J Laparoendosc Adv Surg Tech A. 2020 Aug;30(8):935-938. doi: 10.1089/lap.2020.0289. Epub 2020 Jun 11.
Impact factor: 1.31
Publication type: Paper in international publication
Authors: Gine, Carlos, Lain, Ana, Lopez, Manuel, Garcia, Laura et al.
DOI: 10.1089/lap.2020.0289

Modelling the skeletal muscle injury recovery using in vivo contrast-enhanced micro-CT: a proof-of-concept study in a rat model.

PMID: 32488324
Journal: European radiology experimental
Year: 2020
Reference: Eur Radiol Exp. 2020 Jun 3;4(1):33. doi: 10.1186/s41747-020-00163-4.
Impact factor: 0
Publication type: Paper in international publication
Authors: Paun, Bruno, Leon, Daniel Garcia, Cabello, Alex Claveria, Pages, Roso Mares, de la Calle Vargas, Elena, Munoz, Paola Contreras, Garcia, Vanessa Venegas, Castell-Conesa, Joan, Baleriola, Mario Marotta, Camacho, Jose Raul Herance et al.
DOI: 10.1186/s41747-020-00163-4

Treatment of balanitis xerotica obliterans in pediatric patients.

PMID: 32250071
Journal: Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica
Year: 2020
Reference: Cir Pediatr. 2020 Apr 1;33(2):79-83.
Impact factor: 0
Publication type: Paper in national publication
Authors: Leganes Villanueva, C, Gander, R, Royo Gomes, G, Ezzeddine Ezzeddine, M, Lopez Paredes, M, Asensio Llorente, M et al.
DOI:

Management of neonates with right-sided aortic arch and esophageal atresia: International survey on IPEG AND ESPES members experience.

PMID: 29241961
Journal: JOURNAL OF PEDIATRIC SURGERY
Year: 2018
Reference: J Pediatr Surg. 2018 Oct;53(10):1923-1927. doi: 10.1016/j.jpedsurg.2017.11.051. Epub 2017 Nov 23.
Impact factor: 2.128
Publication type: Review in national publication
Authors: Aguilera-Pujabet, Monserrat, Gahete, Jose Andres Molino, Guillen, Gabriela, Lopez-Fernandez, Sergio, Martin-Gimenez, Marta Patricia, Lloret, Josep, Lopez, Manuel et al.
DOI: 10.1016/j.jpedsurg.2017.11.051

Measured dynamic compression for pectus carinatum: A systematic review.

PMID: 30078489
Journal: Seminars in Pediatric Surgery
Year: 2018
Reference: Semin Pediatr Surg. 2018 Jun;27(3):175-182. doi: 10.1053/j.sempedsurg.2018.06.001. Epub 2018 Jun 15.
Impact factor: 1.645
Publication type: Paper in international publication
Authors: de Beer, Sjoerd A, Blom, Yael E, Lopez, Manuel, de Jong, Justin R et al.
DOI: 10.1053/j.sempedsurg.2018.06.001

Fetoscopic Two-Layers Closure of Open Neural Tube Defects.

PMID: 29876992
Journal: ULTRASOUND IN OBSTETRICS & GYNECOLOGY
Year: 2018
Reference: Ultrasound Obstet Gynecol. 2018 Oct;52(4):452-457. doi: 10.1002/uog.19104. Epub 2018 Sep 10.
Impact factor: 5.654
Publication type: Paper in international publication
Authors: Gine, C, Arevalo, S, Maiz, N, Rodo, C, Manrique, S, Poca, A, Molino, J A, Carreras, E, Lopez, M et al.
DOI: 10.1002/uog.19104

Role of Biodegradable Stents as Part of Treatment of Biliary Strictures after Pediatric and Adult Liver Transplantation: An Observational Single-Center Study.

PMID: 29798761
Journal: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
Year: 2018
Reference: J Vasc Interv Radiol. 2018 Jun;29(6):899-904. doi: 10.1016/j.jvir.2018.02.007.
Impact factor: 2.758
Publication type: Paper in international publication
Authors: Dopazo, Cristina, Diez, Iratxe, Quintero, Jesus, Curell, Anna, Gonzalez-Junyent, Carla, Caralt, Mireia, Pando, Elizabeth, Lazaro, Jose Luis, Molino, Jose Andres, Juamperez, Javier et al.
DOI: 10.1016/j.jvir.2018.02.007

[Current anesthesia risk of anterior mediastinal masses].

PMID: 28481065
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Oct 10;29(4):142-148.
Impact factor: 0
Publication type: Paper in national publication
Authors: Aguilera-Pujabet, M, Guillen, G, Montferrer, N, Lopez-Fernandez, S, Molino, J A, Lloret, J et al.
DOI:

[Vascular interventional radiology: a fundamental procedure for the management of paediatric trauma].

PMID: 27911067
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Jan 25;29(1):25-30.
Impact factor: 0
Publication type: Paper in national publication
Authors: Bordon Cabrera, E, Lain, A, Gander, R, Perez Lafuente, M, Diez Miranda, I, Fontecha, C G, Seidler, L, Delgado, I, Canadas Palazon, S, Lloret, J et al.
DOI:

[Congenital portosistemic shunt. Importance of early treatment].

PMID: 27775284
Journal: Cirugia pediatrica : organo oficial de la Sociedad
Year: 2016
Reference: Cir Pediatr. 2016 Jan 15;28(2):67-73.
Impact factor: 0
Publication type: Paper in national publication
Authors: Perez, M, Gander, R, Segarra, A, Leganes, C, Bueno, J, Vicente, N et al.
DOI:

The quantitative lung index and the prediction of survival in fetuses with congenital diaphragmatic hernia.

PMID: 26871273
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology
Year: 2016
Reference: Eur J Obstet Gynecol Reprod Biol. 2016 Mar;198:145-8. doi: 10.1016/j.ejogrb.2016.01.011. Epub 2016 Jan 11.
Impact factor: 1.662
Publication type: Paper in international publication
Authors: Illescas, Tamara, Rodo, Carlota, Arevalo, Silvia, Gine, Carles, Peiro, Jose L, Carreras, Elena et al.
DOI: 10.1016/j.ejogrb.2016.01.011

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Divuit hores de programa solidari recull més de 8 milions d'euros per lluitar contra les malalties del cor. A Catalunya, una de cada quatre persones moren a causa d'una malaltia del cor o un ictus