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Cardiovascular Diseases

Cardiovascular Diseases group is a translational research group within the Cardiology Department of Vall d’Hebron Hospital that performs laboratory, clinical and epidemiological research. In the CIBERCV network we are within the topic of descriptor 2 “Arterial disease, thrombosis and myocardial ischemia-reperfusion injury”. Our contributions in these topics address the following lines: 

  • Myocardial ischemia-reperfusion injury (i.e. mechanisms of endogenous cardioprotection, ischemic conditioning and remodeling), 
  • Coronary artery disease (i.e. genetic factors involved in coronary artery disease, determinants of thrombotic complications and prognosis), 
  • Aortic diseases (i.e. determinants of aorta dilatation, aortic biomechanics abnormalities in Marfan´s syndrome, and new imaging methods), 
  • Congenital/familiar heart diseases (i.e. genetic determinants and prognosis factors). 

In the CIBERESP network, our group is interested in the study of effectiveness/cost-effectiveness of cardiovascular interventions, health outcome research and methods in clinical research. The group has 19 principal investigators, 32 active projects and clinical trial and has been done 142 publications in 2020.

Publications

Gender differences in outcome in patients with diabetes mellitus.

PMID: 32458331
Journal: JOURNAL OF NUCLEAR CARDIOLOGY
Year: 2022
Reference: J Nucl Cardiol. 2022 Feb;29(1):72-82. doi: 10.1007/s12350-020-02195-0. Epub 2020 May 26.
Impact factor: 5.952
Publication type: Paper in international publication
Authors: Pizzi, Maria Nazarena, Roque, Albert, Candell-Riera, Jaume, Cuellar-Calabria, Hug, Aguade-Bruix, Santiago, Romero-Farina, Guillermo et al.
DOI: 10.1007/s12350-020-02195-0

QTc interval prolongation in patients infected with SARS-CoV-2 and treated with antiviral drugs.

PMID: 35193834
Journal: ANALES DE PEDIATRIA
Year: 2022
Reference: An Pediatr (Engl Ed). 2022 Mar;96(3):213-220. doi: 10.1016/j.anpede.2021.04.006. Epub 2022 Feb 19.
Impact factor: 1.5
Publication type: Paper in international publication
Authors: Esmel-Vilomara, Roger, Dolader, Paola, Sabate-Rotes, Anna, Soriano-Arandes, Antoni, Gran, Ferran, Roses-Noguer, Ferran et al.
DOI: 10.1016/j.anpede.2021.04.006

The role of antibody responses against glycans in bioprosthetic heart valve calcification and deterioration.

PMID: 35177855
Journal: NATURE MEDICINE
Year: 2022
Reference: Nat Med. 2022 Feb;28(2):283-294. doi: 10.1038/s41591-022-01682-w. Epub 2022 Feb 17.
Impact factor: 53.44
Publication type: Paper in international publication
Authors: Ruiz-Majoral, Alejandro, Coste du Fou, Guenola, Leviatan Ben-Arye, Shani, Govani, Liana, Yehuda, Sharon, Bachar Abramovitch, Shirley, Amon, Ron, Reuven, Eliran Moshe, Atiya-Nasagi, Yafit, Yu, Hai et al.
DOI: 10.1038/s41591-022-01682-w

Identification of hemodynamic biomarkers for bicuspid aortic valve induced aortic dilation using machine learning.

PMID: 34929463
Journal: COMPUTERS IN BIOLOGY AND MEDICINE
Year: 2022
Reference: Comput Biol Med. 2022 Feb;141:105147. doi: 10.1016/j.compbiomed.2021.105147. Epub 2021 Dec 16.
Impact factor: 4.589
Publication type: Paper in international publication
Authors: Franco, Pamela, Sotelo, Julio, Guala, Andrea, Dux-Santoy, Lydia, Evangelista, Arturo, Rodriguez-Palomares, Jose, Mery, Domingo, Uribe, Sergio, Salas, Rodrigo et al.
DOI: 10.1016/j.compbiomed.2021.105147

EACVI recommendations on cardiovascular imaging for the detection of embolic sources: endorsed by the Canadian Society of Echocardiography.

PMID: 33709114
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2021
Reference: Eur Heart J Cardiovasc Imaging. 2021 May 10;22(6):e24-e57. doi: 10.1093/ehjci/jeab008.
Impact factor: 6.875
Publication type: Paper in international publication
Authors: Popescu, Bogdan A, Edvardsen, Thor, Dweck, Marc, Sprynger, Muriel, Cohen, Ariel, Donal, Erwan, Pepi, Mauro, Tsang, Teresa, Gerber, Bernhard, Soulat-Dufour, Laurie et al.
DOI: 10.1093/ehjci/jeab008

Central pulse pressure is inversely associated with proximal aortic remodelling.

PMID: 33710165
Journal: JOURNAL OF HYPERTENSION
Year: 2021
Reference: J Hypertens. 2021 May 1;39(5):919-925. doi: 10.1097/HJH.0000000000002730.
Impact factor: 4.844
Publication type: Paper in international publication
Authors: Ridolfi, Luca, Tosello, Francesco, Guala, Andrea, D'ascenzo, Fabrizio, Bollati, Martina, Leone, Dario, Sabia, Luca, Bruno, Giulia, Mingrone, Giulia, Astarita, Anna et al.
DOI: 10.1097/HJH.0000000000002730

A sex paradox in clinical outcomes following complex percutaneous intervention. Treatment bias, biology or both?

PMID: 33388399
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2021
Reference: Int J Cardiol. 2021 Apr 15;329:77-78. doi: 10.1016/j.ijcard.2020.12.072. Epub 2020 Dec 31.
Impact factor: 4.164
Publication type: Editorail in international publication
Authors: Sambola, Antonia, Soriano-Colome, Toni et al.
DOI: 10.1016/j.ijcard.2020.12.072

Perspective and future direction of intraventricular mechanical dyssynchrony assessment.

PMID: 30684259
Journal: JOURNAL OF NUCLEAR CARDIOLOGY
Year: 2021
Reference: J Nucl Cardiol. 2021 Feb;28(1):65-71. doi: 10.1007/s12350-019-01604-3. Epub 2019 Jan 25.
Impact factor: 5.952
Publication type: Editorail in international publication
Authors: Romero-Farina, Guillermo, Aguade-Bruix, Santiago et al.
DOI: 10.1007/s12350-019-01604-3

Determinants of long-term outcome of repaired pulmonary valve stenosis.

PMID: 31130344
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2020
Reference: Rev Esp Cardiol (Engl Ed). 2020 Feb;73(2):131-138. doi: 10.1016/j.rec.2019.02.014. Epub 2019 May 24.
Impact factor: 4.642
Publication type: Paper in national publication
Authors: Galian-Gay, Laura, Gordon, Blanca, Marsal, Josep Ramon, Rafecas, Agnes, Pijuan Domenech, Antonia, Castro, Miguel Angel, Sureda, Carlos, Miranda, Berta, Marti, Gerard, Garcia-Dorado, David et al.
DOI: 10.1016/j.recesp.2019.02.020

Acute Coronary Syndrome Following Transcatheter Aortic Valve Replacement.

PMID: 31992059
Journal: Circulation-Cardiovascular Interventions
Year: 2020
Reference: Circ Cardiovasc Interv. 2020 Feb;13(2):e008620. doi: 10.1161/CIRCINTERVENTIONS.119.008620. Epub 2020 Jan 29.
Impact factor: 5.493
Publication type: Paper in international publication
Authors: Serra, Vicenc, Alperi, Alberto, Nombela-Franco, Luis, Fischer, Quentin, Veiga, Gabriela, Donaint, Pierre, Asmarats, Lluis, Vilalta, Victoria, Chamandi, Chekrallah, Regueiro, Ander et al.
DOI: 10.1161/CIRCINTERVENTIONS.119.008620

A single nucleotide deletion resulting in a frameshift in exon 4 of TAB2 is associated with a polyvalular syndrome.

PMID: 31981616
Journal: European Journal of Medical Genetics
Year: 2020
Reference: Eur J Med Genet. 2020 Apr;63(4):103854. doi: 10.1016/j.ejmg.2020.103854. Epub 2020 Jan 23.
Impact factor: 2.368
Publication type: Letter or abstract
Authors: Blasco-Lucas, Arnau, Maldonado, Giuliana, Amador-Catalan, Amaya, Ferrer-Curriu, Gemma, Fuste, Berta, Perez, Maria L, Gonzalez-Alujas, Teresa, Beltran, Sergi, Comas-Riu, Jaume, Bardaji, Alfredo et al.
DOI: 10.1016/j.ejmg.2020.103854

A novel clinical risk prediction model for myocardial infarction, coronary revascularization, and cardiac death according to clinical, exercise, and gated SPECT variables (VH-RS).

PMID: 31049558
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2020
Reference: Eur Heart J Cardiovasc Imaging. 2020 Feb 1;21(2):210-221. doi: 10.1093/ehjci/jez078.
Impact factor: 4.841
Publication type: Paper in international publication
Authors: Romero-Farina, Guillermo, Candell-Riera, Jaume, Aguade-Bruix, Santiago, Garcia Dorado, David et al.
DOI: 10.1093/ehjci/jez078

Comments on the 2018 ESC/EACTS Guidelines for Myocardial Revascularization.

PMID: 30580785
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Jan;72(1):16-20. doi: 10.1016/j.rec.2018.11.010.
Impact factor: 5.078
Publication type: Review in national publication
Authors: Bueno, Hector, Ibanez, Borja, Bautista-Hernandez, Victor, Alfonso, Fernando, Berga Congost, Gemma, Carnero, Manuel, Viana-Tejedor, Ana, Cid-Alvarez, Belen A, de la Torre Hernandez, Jose Maria, Franco-Pelaez, Juan Antonio et al.
DOI: 10.1016/j.rec.2018.11.010

Comments on the 2018 ESC Fourth Universal Definition of Myocardial.

PMID: 30580784
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2019
Reference: Rev Esp Cardiol (Engl Ed). 2019 Jan;72(1):10-15. doi: 10.1016/j.rec.2018.11.009.
Impact factor: 5.078
Publication type: Review in national publication
Authors: Viana-Tejedor, Ana, Bueno, Hector, Antonio Barrabes, Jose, Delgado, Victoria, Jimenez, Pilar, Jorge Perez, Pablo, Javier Noriega, Francisco, Vila, Montserrat, Aboal, Jaime, Sambola, Antonia et al.
DOI: 10.1016/j.rec.2018.11.009

Preoperative predictive model for acute kidney injury after elective cardiac surgery: a prospective multicenter cohort study.

PMID: 29756690
Journal: Minerva Anestesiologica
Year: 2019
Reference: Minerva Anestesiol. 2019 Jan;85(1):34-44. doi: 10.23736/S0375-9393.18.12257-7. Epub 2018 May 11.
Impact factor: 2.84
Publication type: Paper in international publication
Authors: Pita-Romero, Rafael, Arribas, Pilar, Arteta, Maite, Avila, Elisa, Badenes, Rafael, Ballester, Juan A, Banos, Gerardo, Barado, Julio, Barrios, Jose M, Barrios, Rosa et al.
DOI: 10.23736/S0375-9393.18.12257-7

Implications of Asymmetry and Valvular Morphotype on Echocardiographic Measurements of the Aortic Root in Bicuspid Aortic Valve.

PMID: 30269911
Journal: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Year: 2019
Reference: J Am Soc Echocardiogr. 2019 Jan;32(1):105-112. doi: 10.1016/j.echo.2018.08.004. Epub 2018 Sep 27.
Impact factor: 6.111
Publication type: Paper in international publication
Authors: Vis, Jeroen C, Rodriguez-Palomares, Jose F, Teixido-Tura, Gisela, Galian-Gay, Laura, Granato, Chiara, Guala, Andrea, Sao-Aviles, Augusto, Gutierrez, Laura, Gonzalez-Alujas, Teresa, Garcia-Dorado, David et al.
DOI: 10.1016/j.echo.2018.08.004

Area at risk and collateral circulation in a first acute myocardial infarction with occluded culprit artery. STEMI vs non-STEMI patients.

PMID: 29361353
Journal: INTERNATIONAL JOURNAL OF CARDIOLOGY
Year: 2018
Reference: Int J Cardiol. 2018 May 15;259:14-19. doi: 10.1016/j.ijcard.2018.01.047. Epub 2018 Jan 31.
Impact factor: 4.034
Publication type: Paper in international publication
Authors: Figueras, Jaume, Otaegui, Imanol, Marti, Gerard, Domingo, Enric, Baneras, Jordi, Barrabes, Jose A, Del Blanco, Bruno Garcia, Garcia-Dorado, David et al.
DOI: 10.1016/j.ijcard.2018.01.047

Acute Myocarditis with Infarct-like Presentation in a Pediatric Population: Role of Cardiovascular Magnetic Resonance.

PMID: 28986648
Journal: PEDIATRIC CARDIOLOGY
Year: 2018
Reference: Pediatr Cardiol. 2018 Jan;39(1):51-56. doi: 10.1007/s00246-017-1726-2. Epub 2017 Oct 6.
Impact factor: 1.54
Publication type: Paper in international publication
Authors: Martinez-Villar, Maria, Gran, Ferran, Sabate-Rotes, Anna, Tello-Montoliu, Antonio, Castellote, Amparo, Figueras-Coll, Marc, Ferrer, Queralt, Roses-Noguer, Ferran et al.
DOI: 10.1007/s00246-017-1726-2

False-positive Activations in STEMI Networks: An Unavoidable Toll.

PMID: 29307465
Journal: REVISTA ESPANOLA DE CARDIOLOGIA
Year: 2018
Reference: Rev Esp Cardiol (Engl Ed). 2018 Apr;71(4):234-236. doi: 10.1016/j.rec.2017.10.041. Epub 2018 Jan 5.
Impact factor: 5.166
Publication type: Letter or abstract
Authors: Barrabes, Jose A, Sambola, Antonia et al.
DOI: 10.1016/j.rec.2017.10.041

Recurrent purulent pericarditis secondary to a giant bronchogenic cyst.

PMID: 29029080
Journal: European Heart Journal-Cardiovascular Imaging
Year: 2018
Reference: Eur Heart J Cardiovasc Imaging. 2018 Jan 1;19(1):118. doi: 10.1093/ehjci/jex208.
Impact factor: 8.336
Publication type: Paper in international publication
Authors: Valente, Filipa, Migliori, Maximo, Segura, Cristobal, Rodriguez Palomares, Jose et al.
DOI: 10.1093/ehjci/jex208

Heterogeneity of aortic disease severity in patients with Loeys-Dietz syndrome.

PMID: 26848186
Journal: HEART
Year: 2016
Reference: Heart. 2016 Apr;102(8):626-32. doi: 10.1136/heartjnl-2015-308535. Epub 2016 Feb 4.
Impact factor: 5.693
Publication type: Paper in international publication
Authors: Teixido-Tura, Gisela, Franken, Romy, Galuppo, Valentina, Gutierrez Garcia-Moreno, Laura, Borregan, Mar, Mulder, Barbara J M, Garcia-Dorado, David, Evangelista, Artur et al.
DOI: 10.1136/heartjnl-2015-308535

Impact of Triple Therapy in Elderly Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention.

PMID: 26808678
Journal: PLoS One
Year: 2016
Reference: PLoS One. 2016 Jan 25;11(1):e0147245. doi: 10.1371/journal.pone.0147245. eCollection 2016.
Impact factor: 3.057
Publication type: Paper in international publication
Authors: Bueno, Hector, Alfonso, Fernando, Cequier, Angel, Zueco, Javier, Rodriguez-Leor, Oriol, Tornos, Pilar, Garcia-Dorado, David, Barrabes, Jose A, Alonso, Albert, Mutuberria, Maria et al.
DOI: 10.1371/journal.pone.0147245

Hand-held cardiac ultrasound screening performed by family doctors with remote expert support interpretation.

PMID: 26802099
Journal: PROGRESS IN COMPUTATIONAL FLUID DYNAMICS
Year: 2016
Reference: Heart. 2016 Mar 1;102(5):376-82. doi: 10.1136/heartjnl-2015-308421. Epub 2016 Jan 22.
Impact factor: 0.288
Publication type: Paper in international publication
Authors: Evangelista, Arturo, Galuppo, Valentina, Mendez, Judith, Evangelista, Lidia, Arpal, Lidia, Rubio, Carles, Vergara, Montserrat, Liceran, Manuela, Lopez, Francesc, Sales, Carlos et al.
DOI: 10.1136/heartjnl-2015-308421

Differential Diagnosis and Clinical Implications of Remnants of the Right Valve of the Sinus Venosus.

PMID: 26787493
Journal: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
Year: 2016
Reference: J Am Soc Echocardiogr. 2016 Mar;29(3):183-94. doi: 10.1016/j.echo.2015.11.018. Epub 2016 Jan 16.
Impact factor: 4.254
Publication type: Paper in international publication
Authors: Moral, Sergio, Ballesteros, Esther, Huguet, Marina, Panaro, Alejandro, Palet, Jordi, Evangelista, Arturo et al.
DOI: 10.1016/j.echo.2015.11.018

Blog

News

The European project, in which Vall d'Hebron participates, will favor personalized diagnosis and innovative therapeutic strategies in patients with the disease.

In total, different projects of six research groups will be promoted, focusing on precision medicine and advanced therapies.

The Cardiovascular Diseases and Neurovascular Diseases groups at VHIR will investigate new therapeutic strategies for heart failure, nanomedicine in stroke and the prevention of cardiovascular toxicity in the case of oncological treatments.

Job offers

Pre-doctoral Researcher: Cardiovascular Disease Group
Start date:
07/10/2020
End date:
21/10/2020
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Nurse
Start date:
14/09/2020
End date:
28/09/2020
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Investigator Pre-doctoral: Cardiovascular Diseases Laboratory Group
Start date:
28/07/2020
End date:
11/08/2020
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