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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
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Anna Collado Gimbert

Anna Collado Gimbert

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Espinosa Lopez, Blanca

Espinosa Lopez, Blanca

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Lorena Valero Arrese

Lorena Valero Arrese

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Maria Cristina Díaz de Heredia Rubio

Maria Cristina Díaz de Heredia Rubio

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
Read more
Anna Collado Gimbert

Anna Collado Gimbert

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Espinosa Lopez, Blanca

Espinosa Lopez, Blanca

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Lorena Valero Arrese

Lorena Valero Arrese

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Maria Cristina Díaz de Heredia Rubio

Maria Cristina Díaz de Heredia Rubio

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more

Projects

Implementación de la Oncología de Precisión en Pacientes Adolescentes y Adultos Jóvenes con Cáncer

IP: Lucas Moreno Martín-Retortillo
Collaborators: Implementación de la Oncología de Precisión en Pacientes Adolescentes y Adultos Jóvenes con Cáncer, Maria Paula Pérez Albert
Funding agency: Instituto de Salud Carlos III
Funding: 65000
Reference: CM22/00241
Duration: 01/01/2023 - 31/12/2024

SYNTHEMA: Synthetic generation of hematological data over federated computing frameworks

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Sara Isabel Reidel , Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 435938
Reference: SYNTHEMA_HE-HLTH22_IND13
Duration: 01/12/2022 - 30/11/2026

Desarrollo de una nueva diana terapéutica con elevado potencial anti-oncogénico para los sarcomas infantiles: bloqueo farmacológico del co-receptor de Hedgehog CDO.

IP: Josep Roma Castanyer
Collaborators: -
Funding agency: Fundación Inocente Inocente
Funding: 90000
Reference: INOCENTE/RECERCA/2022/ROMA
Duration: 10/10/2022 - 30/09/2025

Logotip Fundación Inocente Inocente

ERN-EuroBloodNet: EUROPEAN REFERENCE NETWORK ON RARE HEMATOLOGICAL DISEASES

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Claire Diot, Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 371825
Reference: EUROBLOODNETBR2022_EU4H-ERN2022
Duration: 01/05/2022 - 30/11/2023

Blog

News

The European initiative Hope4Kids will strengthen and harmonise paediatric palliative care across Europe, with the aim of ensuring comprehensive, high-quality care for all children living with life-threatening or life-limiting conditions.

The initiative will enable young people aged 12 to 18 to collaborate with campus researchers in the design, development and communication of scientific projects, placing patients and families at the centre of the research process.

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.