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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
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Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
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Alba Albert Robledo

Alba Albert Robledo

Administration and Management
Childhood Cancer and Blood Disorders
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Amalia Varo Rodriguez

Amalia Varo Rodriguez

Senior researcher
Childhood Cancer and Blood Disorders
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Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
Read more
Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
Read more
Alba Albert Robledo

Alba Albert Robledo

Administration and Management
Childhood Cancer and Blood Disorders
Read more
Amalia Varo Rodriguez

Amalia Varo Rodriguez

Senior researcher
Childhood Cancer and Blood Disorders
Read more
Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more

Projects

Desenvolupament de fàrmacs per inhibir la funció del complexe remodelador de la cromatina BAF.

IP: Miguel Segura Ginard
Collaborators: Adria Molero Valenzuela
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 20000
Reference: 2021 LLAV 00002
Duration: 12/10/2022 - 11/07/2023

Nanomedicina basada en RNA per al tractament del càncer.

IP: Miguel Segura Ginard
Collaborators: -
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 100000
Reference: 2021 PROD 00059
Duration: 19/10/2022 - 19/04/2024

Nuevas estrategias de inhibición de la vía Hedgehog como dianas terapéuticas en el rabdomiosarcoma

IP: Josep Roma Castanyer
Collaborators: Guillem Pons Barcons, Nuevas estrategias de inhibición de la vía Hedgehog como dianas terapéuticas en el rabdomiosarcoma
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 63589.78
Reference: 2021 FI_B 00088
Duration: 01/04/2021 - 31/03/2024

Erythrocytes properties and viability in dependence of flow and extra-cellular environment (EVIDENCE)

IP: M Mar Mañu Pereira
Collaborators: Amira Idrizovic
Funding agency: EUROPEAN COMMISSION
Funding: 250904.88
Reference: EVIDENCE_H2020_MSCA-ITN2019
Duration: 01/01/2020 - 31/12/2023

Blog

News

Vall d’Hebron participates as a reference centre in Spain for early-phase clinical trials and coordinates the national ReALLNet network, promoting research into relapsed acute lymphoblastic leukemia.

The PHOENIX project, involving 13 European institutions, will evaluate for the first time in paediatric patients the drug ibrilatazar from AbilityPharma in a phase I/II clinical trial.

The European initiative Hope4Kids will strengthen and harmonise paediatric palliative care across Europe, with the aim of ensuring comprehensive, high-quality care for all children living with life-threatening or life-limiting conditions.