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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
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Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
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Esther García Pagès

Esther García Pagès

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Gal·la Farreny Fernández

Gal·la Farreny Fernández

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
Read more
Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
Read more
Esther García Pagès

Esther García Pagès

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Gal·la Farreny Fernández

Gal·la Farreny Fernández

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more

Projects

Estudio fase IV, aleatorizado, abierto, controlado para evaluar la terminación temprana del tratamiento con antibioticos en pacientes oncohematológicos con neutropenia febril (e-STOP

IP: Pere Soler Palacín
Collaborators: Luís Gros Subias, Juliana Esperalba Esquerra, Natalia Ana Mendoza Palomar, Núria Worner Tomasa, Susana Melendo Perez
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI19/01522
Duration: 01/01/2020 - 30/06/2024

TRASLACIÓN DE UN PRODUCTO DE INGENIERÍA TISULAR ALOGÉNICO CON MSC DE GELATINA DE WHARTON PARA EL TRATAMIENTO DE LA OSTEONECROSIS EN PACIENTES ONCOLÓGICOS PEDIÁTRICOS.

IP: Joaquim Vives Armengol
Collaborators: Roberto Vélez Villa, Nayana Joshi Jubert, Lluis Martorell Cedres, Maria Cristina Díaz de Heredia Rubio, Màrius Aguirre Canyadell, Irene Portas Torres, Raquel Cabrera Perez
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI19/01788
Duration: 01/01/2020 - 30/06/2024

Liquid biopsy in paediatric sarcomas: deciphering the predictive potential of circulating tumour DNA and tumour-derived exosomes for early relapse detection

IP: Josep Roma Castanyer
Collaborators: Lia Garcia Gilabert
Funding agency: Fundació La Marató de TV3
Funding: 170000
Reference: 20193730
Duration: 29/10/2020 - 31/12/2023

European Rare Blood Disorders Platform - ENROL

IP: M Mar Mañu Pereira
Collaborators: Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 93954.6
Reference: ENROL_HP-PJ-01-2019
Duration: 01/06/2020 - 31/05/2023

Blog

News

Vall d’Hebron participates as a reference centre in Spain for early-phase clinical trials and coordinates the national ReALLNet network, promoting research into relapsed acute lymphoblastic leukemia.

The PHOENIX project, involving 13 European institutions, will evaluate for the first time in paediatric patients the drug ibrilatazar from AbilityPharma in a phase I/II clinical trial.

The European initiative Hope4Kids will strengthen and harmonise paediatric palliative care across Europe, with the aim of ensuring comprehensive, high-quality care for all children living with life-threatening or life-limiting conditions.