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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Ariadna Miquel Clopés

Ariadna Miquel Clopés

Research technician
Childhood Cancer and Blood Disorders
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Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
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Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
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Ángela Menárguez López

Ángela Menárguez López

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Ariadna Miquel Clopés

Ariadna Miquel Clopés

Research technician
Childhood Cancer and Blood Disorders
Read more
Braulio Andrés Ortega Quesada

Braulio Andrés Ortega Quesada

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Clara Rey Valenzuela

Clara Rey Valenzuela

Research technician
Childhood Cancer and Blood Disorders
Read more
Clara Serra Marrugat

Clara Serra Marrugat

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Daiana Natali Lopez

Daiana Natali Lopez

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

Estudio fase IV, aleatorizado, abierto, controlado para evaluar la terminación temprana del tratamiento con antibioticos en pacientes oncohematológicos con neutropenia febril (e-STOP

IP: Pere Soler Palacín
Collaborators: Luís Gros Subias, Juliana Esperalba Esquerra, Natalia Ana Mendoza Palomar, Núria Worner Tomasa, Susana Melendo Perez
Funding agency: Instituto de Salud Carlos III
Funding: 135520
Reference: PI19/01522
Duration: 01/01/2020 - 30/06/2024

TRASLACIÓN DE UN PRODUCTO DE INGENIERÍA TISULAR ALOGÉNICO CON MSC DE GELATINA DE WHARTON PARA EL TRATAMIENTO DE LA OSTEONECROSIS EN PACIENTES ONCOLÓGICOS PEDIÁTRICOS.

IP: Joaquim Vives Armengol
Collaborators: Roberto Vélez Villa, Nayana Joshi Jubert, Lluis Martorell Cedres, Maria Cristina Díaz de Heredia Rubio, Màrius Aguirre Canyadell, Irene Portas Torres, Raquel Cabrera Perez
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI19/01788
Duration: 01/01/2020 - 30/06/2024

Liquid biopsy in paediatric sarcomas: deciphering the predictive potential of circulating tumour DNA and tumour-derived exosomes for early relapse detection

IP: Josep Roma Castanyer
Collaborators: Lia Garcia Gilabert
Funding agency: Fundació La Marató de TV3
Funding: 170000
Reference: 20193730
Duration: 29/10/2020 - 31/12/2023

European Rare Blood Disorders Platform - ENROL

IP: M Mar Mañu Pereira
Collaborators: Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 93954.6
Reference: ENROL_HP-PJ-01-2019
Duration: 01/06/2020 - 31/05/2023

Blog

News

The integration of Patient-Reported Outcome Measures (PROMs) will make it possible to incorporate patients' experiences and quality of life into research on sickle cell disease and other rare anaemias.

The Scientific Coordinator of ERN-EuroBloodNet will lead for one year the group that defines the common strategy of the European Reference Networks to improve care for rare and complex diseases.

Vall d’Hebron participates as a reference centre in Spain for early-phase clinical trials and coordinates the national ReALLNet network, promoting research into relapsed acute lymphoblastic leukemia.