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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

David Silva Soto

David Silva Soto

Research technician
Childhood Cancer and Blood Disorders
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Esther García Pagès

Esther García Pagès

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Flors Riera Enseñat

Flors Riera Enseñat

Research technician
Childhood Cancer and Blood Disorders
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Gal·la Farreny Fernández

Gal·la Farreny Fernández

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Gemma Montagut Pino

Gemma Montagut Pino

Senior researcher
Childhood Cancer and Blood Disorders
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Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
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David Silva Soto

David Silva Soto

Research technician
Childhood Cancer and Blood Disorders
Read more
Esther García Pagès

Esther García Pagès

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Flors Riera Enseñat

Flors Riera Enseñat

Research technician
Childhood Cancer and Blood Disorders
Read more
Gal·la Farreny Fernández

Gal·la Farreny Fernández

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Gemma Montagut Pino

Gemma Montagut Pino

Senior researcher
Childhood Cancer and Blood Disorders
Read more
Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

NEW NANOTOOLS FOR THE TREATMENT OF METASTATIC NEUROBLASTOMA

IP: Miguel Segura Ginard
Collaborators: Soledad Gallego Melcón
Funding agency: Instituto de Salud Carlos III
Funding: 208120
Reference: PI20/00530
Duration: 01/01/2021 - 31/12/2023

ENABLING PERSONALIZED MEDICINE OF SICKLE CELL DISEASE PATIENTS BASED ON INTEGRATIVE DIAGNOSIS OF NEW GENERATION METHODOLOGIES

IP: M Mar Mañu Pereira
Collaborators: Pablo Velasco Puyó, Bárbara Tazón Vega, David Beneitez Pastor, Maria Cristina Díaz de Heredia Rubio, Adoración Blanco Alvarez, Thaïs Murciano Carrillo, Amira Idrizovic
Funding agency: Instituto de Salud Carlos III
Funding: 99220
Reference: PI20/01454
Duration: 01/01/2021 - 30/06/2025

ERICA - European Rare dIsease research Coordination and support Action

IP: M Mar Mañu Pereira
Collaborators: Raquel Mosull del Campo, Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 105250
Reference: ERICA_H2020-SC1-BHC-2020_2020
Duration: 01/03/2021 - 31/08/2025

GENOMED4ALL - Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Esther García Pagès, Anna Collado Gimbert, Ángela Menárguez López, Amira Idrizovic
Funding agency: EUROPEAN COMMISSION
Funding: 434000
Reference: GENOMED4ALL_H2020-SC1-FA-DTS-2018-20_2020
Duration: 01/01/2021 - 30/06/2025

Blog

News

The project’s 4th annual meeting was recently held as part of the Fortalece–Salud programme of the Carlos III Health Institute.

Vall d'Hebron is one of the centers that coordinate this network, which so far has enabled the detection of high-risk genetic alterations and the provision of personalized treatments that have already achieved remission in cases with very few therapeutic alternatives.

The projects, selected under the 2026 Health Research and CaixaImpulse Health Innovation calls, address topics ranging from new therapies for childhood neurological disorders and Parkinson’s disease to the treatment of mitochondrial diseases and cancer.