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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Irene Cafferati

Irene Cafferati

Research technician
Childhood Cancer and Blood Disorders
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Isabel de Rojas de Pablo

Isabel de Rojas de Pablo

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
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Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Irene Cafferati

Irene Cafferati

Research technician
Childhood Cancer and Blood Disorders
Read more
Isabel de Rojas de Pablo

Isabel de Rojas de Pablo

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
Read more
Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

GENOMED4ALL - Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Amira Idrizovic , Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 434000
Reference: GENOMED4ALL_H2020-SC1-FA-DTS-2018-20
Duration: 01/01/2021 - 30/06/2025

International integrated analysis to identify markers of poor survival in high-risk neuroblastoma

IP: Lucas Moreno Martín-Retortillo
Collaborators: Andrea Vilaplana Blanes, Mariona Morell Daniel
Funding agency: Solving Kids’ Cancer
Funding: 131766.91
Reference: SKC/AEFRM/2020/MORENO
Duration: 02/11/2020 - 01/11/2023

BEACON-BIO: deep biological characterisation and development of biomarkers for relapsed neuroblastoma

IP: Lucas Moreno Martín-Retortillo
Collaborators: Andrea Vilaplana Blanes, BEACON-BIO: deep biological characterisation and development of biomarkers for relapsed neuroblastoma
Funding agency: European Science Foundation
Funding: 104500
Reference: BEACON-BIO_FKC_2021
Duration: 01/01/2022 - 30/09/2025

Desarrollo de nuevos fármacos basados en la inhibición de los co-receptores de la vía Hedgehog

IP: Josep Roma Castanyer
Collaborators: Soledad Gallego Melcón, Guillem Pons Barcons, Constantino Sábado Álvarez, Raquel Hladun Alvaro, Patricia Zarzosa Martinez
Funding agency: Instituto de Salud Carlos III
Funding: 122815
Reference: PI21/00640
Duration: 01/01/2022 - 31/12/2025

Blog

News

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.

In-depth knowledge of tumours helps identify specific alterations and enables the provision of targeted therapies for each patient.

The charitable initiative created in honor of Pol is supporting a research project aimed at identifying therapeutic targets to treat a rare type of leukemia.