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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Lucía Quesada Albacete

Lucía Quesada Albacete

Research technician
Childhood Cancer and Blood Disorders
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Maria Gallego Rodriguez

Maria Gallego Rodriguez

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Maria Jesus Rodríguez Rodríguez

Maria Jesus Rodríguez Rodríguez

Research technician
Childhood Cancer and Blood Disorders
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Maria Luz Uría Oficialdegui

Maria Luz Uría Oficialdegui

Predoctoral researcher
Childhood Cancer and Blood Disorders
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María Paula Pérez Albert

María Paula Pérez Albert

Main researcher
Childhood Cancer and Blood Disorders
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María Victoria Cerezo Morales

María Victoria Cerezo Morales

Administration and Management
Childhood Cancer and Blood Disorders
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Lucía Quesada Albacete

Lucía Quesada Albacete

Research technician
Childhood Cancer and Blood Disorders
Read more
Maria Gallego Rodriguez

Maria Gallego Rodriguez

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Maria Jesus Rodríguez Rodríguez

Maria Jesus Rodríguez Rodríguez

Research technician
Childhood Cancer and Blood Disorders
Read more
Maria Luz Uría Oficialdegui

Maria Luz Uría Oficialdegui

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
María Paula Pérez Albert

María Paula Pérez Albert

Main researcher
Childhood Cancer and Blood Disorders
Read more
María Victoria Cerezo Morales

María Victoria Cerezo Morales

Administration and Management
Childhood Cancer and Blood Disorders
Read more

Projects

Next generation personalised medicine for childhood cancers

IP: Lucas Moreno Martín-Retortillo
Collaborators: Aroa Soriano Fernández, Jessica Camacho Soriano, Raquel Hladun Alvaro, Gabriela Guillén Burrieza, Andrea Vilaplana Blanes, Lorena Valero Arrese, Mariona Morell Daniel
Funding agency: Instituto de Salud Carlos III
Funding: 214170
Reference: PI21/01661
Duration: 01/01/2022 - 30/06/2026

A phase I trial of ABTL0812 in paediatric patients with advanced cancer including neuroblastoma

IP: Lucas Moreno Martín-Retortillo
Collaborators: Soledad Gallego Melcón, Cristina Gamez Cenzano, Aroa Soriano Fernández, Luis Riera Soler, Miguel Segura Ginard, Carlota Aguilera Ordoñez
Funding agency: Instituto de Salud Carlos III
Funding: 826760.77
Reference: ICI21/00076
Duration: 01/01/2022 - 31/12/2025

Implementation and new biomarker development for Personalised Medicine for Childhood Cancers in Spain

IP: Lucas Moreno Martín-Retortillo
Collaborators: Aroa Soriano Fernández, Miguel Segura Ginard, Lorena Valero Arrese, Raquel Hladun Alvaro, Elena Antima Martinez Saez, Marta Sese Faustino, Gabriela Guillén Burrieza, Josep Roma Castanyer, Andrea Vilaplana Blanes, Estela Carrasco López, Margarita Ortega Blanco, Implementation and new biomarker development for Personalised Medicine for Childhood Cancers in Spain, Asbleidy Carolina Torres Barbosa, Berta Campos Estela
Funding agency: Instituto de Salud Carlos III
Funding: 369260
Reference: PMP21/00073
Duration: 01/01/2022 - 31/12/2025

Blog

News

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.

In-depth knowledge of tumours helps identify specific alterations and enables the provision of targeted therapies for each patient.

The charitable initiative created in honor of Pol is supporting a research project aimed at identifying therapeutic targets to treat a rare type of leukemia.