About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
IP: Josep Roma Castanyer Collaborators: - Funding agency: Fundación Inocente Inocente Funding: 90000 Reference: INOCENTE/RECERCA/2022/ROMA Duration: 10/10/2022 - 30/09/2025
IP: Miguel Segura Ginard Collaborators: Nanomedicina basada en RNA per al tractament del càncer. Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 100000 Reference: 2021 PROD 00059 Duration: 19/10/2022 - 19/04/2024
IP: Josep Roma Castanyer Collaborators: Guillem Pons Barcons, Judit Álvarez González Funding agency: Agència Gestió Ajuts Universitaris i de Recerca Funding: 63589.78 Reference: 2021 FI_B 00088 Duration: 01/04/2021 - 31/03/2024
IP: Pere Soler Palacín Collaborators: Luís Gros Subias, Juliana Esperalba Esquerra, Natalia Ana Mendoza Palomar, Núria Worner Tomasa, Susana Melendo Perez Funding agency: Instituto de Salud Carlos III Funding: 135520 Reference: PI19/01522 Duration: 01/01/2020 - 30/06/2024
PMID: 37165368 Journal: Health and Quality of Life Outcomes Year: 2023 Reference: Health Qual Life Outcomes. 2023 May 10;21(1):42. doi: 10.1186/s12955-023-02120-2. Impact factor: Publication type: Paper in international publication Authors: Alonso-Garcia, Lucia; Bruguera, Andreu; Casabona, Jordi; Diaz, Yesika; Egea-Cortes, Laia; Folch, Cinta; Forero, Carlos G; Hernandez, Juan; Mesias-Gazmuri, Jocelyn; Miro, Jose M et al. DOI: 10.1186/s12955-023-02120-2
PMID: 37882449 Journal: Future Oncology Year: 2023 Reference: Future Oncol. 2023 Oct 26. doi: 10.2217/fon-2023-0526. Impact factor: Publication type: Paper in international publication Authors: Agarwal, Neeraj; Alonso, Lucia; Azad, Arun A; Bordas, Anna; Casabona, Jordi; Chakrabarti, Jayeta; Chen, Hsiang-Chun; Colom-Cadena, Andreu; Fizazi, Karim; Ganem, Fabiana et al. DOI: 10.2217/fon-2023-0526
PMID: 37916501 Journal: Future Oncology Year: 2023 Reference: Future Oncol. 2023 Nov 2. doi: 10.2217/fon-2023-0155. Impact factor: Publication type: Paper in international publication Authors: Baik, Christina S; Boral, Andy L; Bowles, Daniel W; Chakravorty, Subarna; Colombatti, Raffaella; Curigliano, Giuseppe; de Montalembert, Mariane; Del Mar Manu Pereira, Maria; Gainor, Justin F; Garralda, Elena et al. DOI: 10.2217/fon-2023-0155
PMID: 37964360 Journal: BREAST CANCER RESEARCH Year: 2023 Reference: Breast Cancer Res. 2023 Nov 14;25(1):143. doi: 10.1186/s13058-023-01736-y. Impact factor: Publication type: Paper in international publication Authors: Baulida, Josep; Benitez-Carbante, Maria Isabel; Diaz de Heredia, Cristina; Eyras, Eduardo; Fernandez Ledesma, Berta; Fernandez-Polo, Aurora; Franco-Valls, Hector; Garcia de Herreros, Antonio; Grau Cerrato, Santiago; Iaconcig, Alessandra et al. DOI: 10.1186/s13058-023-01736-y
PMID: 35344745 Journal: Cancer Epidemiology Year: 2022 Reference: Cancer Epidemiol. 2022 Jun;78:102145. doi: 10.1016/j.canep.2022.102145. Epub 2022 Mar 25. Impact factor: 2.984 Publication type: Paper in international publication Authors: Pardo-Romaguera, Elena, Segura, Vanessa, Munoz-Lopez, Ana, Galceran-Padros, Jaume, Fernandez-Teijeiro, Ana, Gatta, Gemma, Cruz, O, Benito, A I, Buedo, M I, Calvo, C et al. DOI: 10.1016/j.canep.2022.102145
PMID: 35614316 Journal: BONE MARROW TRANSPLANTATION Year: 2022 Reference: Bone Marrow Transplant. 2022 May 25. pii: 10.1038/s41409-022-01722-6. doi: 10.1038/s41409-022-01722-6. Impact factor: 5.483 Publication type: Letter whit IF Authors: Talarn, Carme, Cid, Joan, Azqueta, Carmen, Valdivia, Elena, Martorell, Lluis, Codinach, Margarita, Marsal, Julia, Mussetti, Alberto, Esquirol, Albert, Trabazo, Maria et al. DOI: 10.1038/s41409-022-01722-6
PMID: 35580896 Journal: International Journal of Laboratory Hematology Year: 2022 Reference: Int J Lab Hematol. 2022 May 17. doi: 10.1111/ijlh.13878. Impact factor: 2.877 Publication type: Letter whit IF Authors: Faneca, Joana, Moreno-Castano, Ana Belen, Diaz-Ricart, Maribel, Escolar, Gines, Garcia, Estefania, Manu-Pereira, Maria Del Mar, Idrizovic, Amira, Matute, Monica, Molina, Angel, Merino, Anna et al. DOI: 10.1111/ijlh.13878
PMID: 35574376 Journal: Frontiers in Oncology Year: 2022 Reference: Front Oncol. 2022 Apr 27;12:835642. doi: 10.3389/fonc.2022.835642. eCollection 2022. Impact factor: 6.244 Publication type: Paper in international publication Authors: Cassandri, Matteo, Perrone, Clara, Pomella, Silvia, Colletti, Marta, Cossetti, Cristina, Pericoli, Giulia, Di Giannatale, Angela, de Billy, Emmanuel, Vinci, Maria, Petrini, Stefania et al. DOI: 10.3389/fonc.2022.835642
PMID: 34212338 Journal: Clinical & Translational Oncology Year: 2021 Reference: Clin Transl Oncol. 2021 Dec;23(12):2460-2473. doi: 10.1007/s12094-021-02654-1. Epub 2021 Jul 1. Impact factor: 3.405 Publication type: Paper in international publication Authors: Ruano, D, Rubio, P, Verges, R, Valverde, C, Gallego, S, Bernabeu, D, Hindi, N, Mata, C, Marquez, C, Orcajo, J et al. DOI: 10.1007/s12094-021-02654-1
PMID: 34193899 Journal: Scientific Reports Year: 2021 Reference: Sci Rep. 2021 Jun 30;11(1):13553. doi: 10.1038/s41598-021-92747-2. Impact factor: 4.38 Publication type: Paper in international publication Authors: Rizzuto, Valeria, Mencattini, Arianna, Alvarez-Gonzalez, Begona, Di Giuseppe, Davide, Martinelli, Eugenio, Beneitez-Pastor, David, Lopez-Martinez, Maria Jose, Samitier, Josep, Manu-Pereira, Maria Del Mar et al. DOI: 10.1038/s41598-021-92747-2
PMID: 33231901 Journal: Transplant Infectious Disease Year: 2021 Reference: Transpl Infect Dis. 2021 Jun;23(3):e13525. doi: 10.1111/tid.13525. Epub 2020 Dec 7. Impact factor: 2.228 Publication type: Review in international publication Authors: Soques Vallejo, Elena, Roca, Isabel, Navarro, Alexandra, Diaz-de-Heredia, Cristina, Benitez-Carabante, Maria Isabel, Valero Arrese, Lorena et al. DOI: 10.1111/tid.13525
PMID: 34127808 Journal: BONE MARROW TRANSPLANTATION Year: 2021 Reference: Bone Marrow Transplant. 2021 Oct;56(10):2489-2496. doi: 10.1038/s41409-021-01367-x. Epub 2021 Jun 14. Impact factor: 5.483 Publication type: Paper in international publication Authors: Linares, Monica, Ancochea, Agueda, Garcia-Rey, Enric, Garcia-Munoz, Nadia, Medina, Laura, Castillo, Nerea, Carreras, Enric, Villa, Juliana, Querol, Sergio, Valcarcel, David et al. DOI: 10.1038/s41409-021-01367-x
PMID: 32593520 Journal: ANALES DE PEDIATRIA Year: 2020 Reference: An Pediatr (Barc). 2020 Aug;93(2):132-133. doi: 10.1016/j.anpedi.2020.05.002. Epub 2020 Jun 9. Impact factor: 1.313 Publication type: Letter whit IF Authors: Velasco Puyo, Pablo, Riviere, Jacques G, Soler Palacin, Pere, Diaz de Heredia, Cristina, Moreno, Lucas et al. DOI: 10.1016/j.anpedi.2020.05.002
PMID: 32554315 Journal: EUROPEAN JOURNAL OF CANCER Year: 2020 Reference: Eur J Cancer. 2020 Aug;135:89-97. doi: 10.1016/j.ejca.2020.04.031. Epub 2020 Jun 15. Impact factor: 7.275 Publication type: Paper in international publication Authors: Amoroso, Loredana, Castel, Victoria, Bisogno, Gianni, Casanova, Michela, Marquez-Vega, Catalina, Chisholm, Julia C, Doz, Francois, Moreno, Lucas, Ruggiero, Antonio, Gerber, Nicolas U et al. DOI: 10.1016/j.ejca.2020.04.031
PMID: 32558231 Journal: PEDIATRIC BLOOD & CANCER Year: 2020 Reference: Pediatr Blood Cancer. 2020 Oct;67(10):e28351. doi: 10.1002/pbc.28351. Epub 2020 Jun 18. Impact factor: 2.355 Publication type: Paper in international publication Authors: Brennan, Bernadette, Zanetti, Ilaria, De Salvo, Gian Luca, Orbach, Daniel, Gallego, Soledad, Francotte, Nadine, Schifflers, Stefan, Van Noesel, Max, Kelsey, Anna, Casanova, Michela et al. DOI: 10.1002/pbc.28351
PMID: 32523362 Journal: ClinicoEconomics and outcomes research : CEOR Year: 2020 Reference: Clinicoecon Outcomes Res. 2020 May 15;12:253-264. doi: 10.2147/CEOR.S241880. eCollection 2020. Impact factor: 0 Publication type: Paper in international publication Authors: Ribera Santasusana, Josep Maria, de Andres Saldana, Alejandra, Garcia-Munoz, Nuria, Gostkorzewicz, Joana, Martinez Llinas, Diana, Diaz de Heredia, Cristina et al. DOI: 10.2147/CEOR.S241880
PMID: 30828868 Journal: EUROPEAN JOURNAL OF HAEMATOLOGY Year: 2019 Reference: Eur J Haematol. 2019 Jun;102(6):465-471. doi: 10.1111/ejh.13226. Epub 2019 Apr 10. Impact factor: 2.217 Publication type: Paper in international publication Authors: Heras, Inmaculada, Viguria, M, Batlle, M, Vazquez, L, Lopez, J, Solano, C, Gonzalez Vicent, M, Suarez-Lledo, M, Alonso, L, Garcia, E et al. DOI: 10.1111/ejh.13226
PMID: 30782268 Journal: Eurosurveillance Year: 2019 Reference: Euro Surveill. 2019 Feb;24(7). doi: 10.2807/1560-7917.ES.2019.24.7.1700857. Impact factor: 7.421 Publication type: Review in international publication Authors: Martinez-Gomez, Xavier, Curran, Adrian, Campins, Magda, Alemany, Laia, Rodrigo-Pendas, Jose Angel, Borruel, Natalia, Castellsague, Xavier, Diaz-de-Heredia, Cristina, Moraga-Llop, Fernando A, Del Pino, Marta et al. DOI: 10.2807/1560-7917.ES.2019.24.7.1700857
PMID: 30770954 Journal: CELLULAR AND MOLECULAR LIFE SCIENCES Year: 2019 Reference: Cell Mol Life Sci. 2019 Jun;76(11):2231-2243. doi: 10.1007/s00018-019-03041-4. Epub 2019 Feb 15. Impact factor: 7.014 Publication type: Paper in international publication Authors: Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masia, Nuria, Paris-Coderch, Laia, Piskareva, Olga, Jimenez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank et al. DOI: 10.1007/s00018-019-03041-4
PMID: 30733543 Journal: BONE MARROW TRANSPLANTATION Year: 2019 Reference: Bone Marrow Transplant. 2019 Jul;54(7):1176. doi: 10.1038/s41409-019-0471-y. Impact factor: 4.674 Publication type: Letter or abstract Authors: Lopez-Corral, Lucia, Perez, Ariadna, Jimenez, Maria Jose, Sanchez-Ortega, Isabel, Alonso, Laura, Sisinni, Luisa, Fox, Laura, Villacampa, Guillermo, Badell, Isabel, de Heredia, Cristina Diaz et al. DOI: 10.1038/s41409-019-0471-y
PMID: 29286582 Journal: PEDIATRIC BLOOD & CANCER Year: 2018 Reference: Pediatr Blood Cancer. 2018 Apr;65(4). doi: 10.1002/pbc.26942. Epub 2017 Dec 29. Impact factor: 2.646 Publication type: Paper in international publication Authors: Ferrari, Andrea, Bisogno, Gianni, De Salvo, Gian Luca, Casanova, Michela, Brennan, Bernadette, Zanetti, Ilaria, Orbach, Daniel, Gallego, Soledad, Francotte, Nadine, Van Noesel, Max et al. DOI: 10.1002/pbc.26942
PMID: 29211298 Journal: CANCER Year: 2018 Reference: Cancer. 2018 Mar 1;124(5):1016-1024. doi: 10.1002/cncr.31157. Epub 2017 Dec 6. Impact factor: 6.537 Publication type: Paper in international publication Authors: Vaarwerk, Bas, van der Lee, Johanna H, Breunis, Willemijn B, Orbach, Daniel, Chisholm, Julia C, Cozic, Nathalie, Jenney, Meriel, van Rijn, Rick R, McHugh, Kieran, Gallego, Soledad et al. DOI: 10.1002/cncr.31157
PMID: 28287638 Journal: BONE MARROW TRANSPLANTATION Year: 2017 Reference: Bone Marrow Transplant. 2017 Jul;52(7):1029-1035. doi: 10.1038/bmt.2017.21. Epub 2017 Mar 13. Impact factor: 3.874 Publication type: Paper in international publication Authors: Dalle, J-H, Lucchini, G, Balduzzi, A, Ifversen, M, Jahnukainen, K, Macklon, K T, Ahler, A, Jarisch, A, Ansari, M, Beohou, E et al. DOI: 10.1038/bmt.2017.21
PMID: 28279690 Journal: ANALES DE PEDIATRIA Year: 2017 Reference: An Pediatr (Barc). 2017 Sep;87(3):155-163. doi: 10.1016/j.anpedi.2016.07.007. Epub 2017 Mar 6. Impact factor: 1.14 Publication type: Review in national publication Authors: Hladun, Raquel, Juan Ribelles, Antonio, Madero, Luis, Ramirez, Manuel, Fernandez Delgado, Rafael, Perez-Martinez, Antonio, Mata, Cristina, Llort, Anna, Martin Broto, Javier, Cela, Maria Elena et al. DOI: 10.1016/j.anpedi.2016.07.007
PMID: 28243259 Journal: Stem Cells International Year: 2017 Reference: Stem Cells Int. 2017;2017:7507380. doi: 10.1155/2017/7507380. Epub 2017 Jan 24. Impact factor: 3.54 Publication type: Paper in international publication Authors: Almazan-Moga, Ana, Zarzosa, Patricia, Vidal, Isaac, Molist, Carla, Giralt, Irina, Navarro, Natalia, Soriano, Aroa, Segura, Miguel F, Alfranca, Arantza, Garcia-Castro, Javier et al. DOI: 10.1155/2017/7507380
PMID: 28205365 Journal: PEDIATRIC BLOOD & CANCER Year: 2017 Reference: Pediatr Blood Cancer. 2017 Sep;64(9). doi: 10.1002/pbc.26486. Epub 2017 Feb 16. Impact factor: 2.513 Publication type: Paper in international publication Authors: Rogers, Timothy, Minard-Colin, Veronique, Cozic, Nathalie, Jenney, Meriel, Merks, Johannes H M, Gallego, Soledad, Devalck, Christine, Gaze, Mark N, Kelsey, Anna, Oberlin, Odile et al. DOI: 10.1002/pbc.26486
The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.
A study jointly led by the Hospital Clínic of Barcelona and the Vall d'Hebron Research Institute (VHIR) confirms the effectiveness of neonatal screening in reducing morbidity among children with sickle cell disease (SCD).
Active participation by patients and families in studies helps identify more effective therapies that improve quality of life and survival.
