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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Irene Cafferati

Irene Cafferati

Research technician
Childhood Cancer and Blood Disorders
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Isabel de Rojas de Pablo

Isabel de Rojas de Pablo

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
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Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Irene Cafferati

Irene Cafferati

Research technician
Childhood Cancer and Blood Disorders
Read more
Isabel de Rojas de Pablo

Isabel de Rojas de Pablo

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
Read more
Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

TRASLACIÓN DE UN PRODUCTO DE INGENIERÍA TISULAR ALOGÉNICO CON MSC DE GELATINA DE WHARTON PARA EL TRATAMIENTO DE LA OSTEONECROSIS EN PACIENTES ONCOLÓGICOS PEDIÁTRICOS.

IP: Joaquim Vives Armengol
Collaborators: Roberto Vélez Villa, Nayana Joshi Jubert, Lluis Martorell Cedres, Maria Cristina Díaz de Heredia Rubio, Màrius Aguirre Canyadell, Irene Portas Torres, Raquel Cabrera Perez
Funding agency: Instituto de Salud Carlos III
Funding: 87120
Reference: PI19/01788
Duration: 01/01/2020 - 30/06/2024

ENABLING PERSONALIZED MEDICINE OF SICKLE CELL DISEASE PATIENTS BASED ON INTEGRATIVE DIAGNOSIS OF NEW GENERATION METHODOLOGIES

IP: M Mar Mañu Pereira
Collaborators: Pablo Velasco Puyó, Bárbara Tazón Vega, David Beneitez Pastor, Maria Cristina Díaz de Heredia Rubio, Adoración Blanco Alvarez, Thaïs Murciano Carrillo, Amira Idrizovic
Funding agency: Instituto de Salud Carlos III
Funding: 99220
Reference: PI20/01454
Duration: 01/01/2021 - 30/06/2025

ERICA - European Rare dIsease research Coordination and support Action

IP: M Mar Mañu Pereira
Collaborators: Claire Diot, Raquel Mosull del Campo
Funding agency: EUROPEAN COMMISSION
Funding: 105250
Reference: ERICA_H2020-SC1-BHC-2020
Duration: 01/03/2021 - 31/08/2025

GENOMED4ALL - Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Amira Idrizovic , Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 434000
Reference: GENOMED4ALL_H2020-SC1-FA-DTS-2018-20
Duration: 01/01/2021 - 30/06/2025

Blog

News

The initiative will enable young people aged 12 to 18 to collaborate with campus researchers in the design, development and communication of scientific projects, placing patients and families at the centre of the research process.

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.

In-depth knowledge of tumours helps identify specific alterations and enables the provision of targeted therapies for each patient.