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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Thaïs Murciano Carrillo

Thaïs Murciano Carrillo

Childhood Cancer and Blood Disorders
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Valeria Rizzuto

Valeria Rizzuto

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Victoria Gutierrez Valle

Victoria Gutierrez Valle

Research technician
Childhood Cancer and Blood Disorders
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Thaïs Murciano Carrillo

Thaïs Murciano Carrillo

Childhood Cancer and Blood Disorders
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Valeria Rizzuto

Valeria Rizzuto

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Victoria Gutierrez Valle

Victoria Gutierrez Valle

Research technician
Childhood Cancer and Blood Disorders
Read more

Publications

Challenges in early phase clinical trials for childhood cancer during the COVID-19 pandemic: a report from the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP).

PMID: 32472454
Journal: Clinical & Translational Oncology
Year: 2021
Reference: Clin Transl Oncol. 2021 Jan;23(1):183-189. doi: 10.1007/s12094-020-02399-3. Epub 2020 May 29.
Impact factor: 3.405
Publication type: Paper in international publication
Authors: Verdu-Amoros, J, Hladun, R, Juan-Ribelles, A, Molero, M, Guerra-Garcia, P, Perez-Martinez, A, Castaneda, A, Canete, A, de Rojas, T, Moreno, L et al.
DOI: 10.1007/s12094-020-02399-3

Failure of Viral-Specific T Cells Administered in Pre-transplant Settings in Children with Inborn Errors of Immunity.

PMID: 33462728
Journal: JOURNAL OF CLINICAL IMMUNOLOGY
Year: 2021
Reference: J Clin Immunol. 2021 May;41(4):748-755. doi: 10.1007/s10875-020-00961-w. Epub 2021 Jan 18.
Impact factor: 8.317
Publication type: Paper in international publication
Authors: Alonso, Laura, Mendez-Echevarria, Ana, Rudilla, Francesc, Mozo, Yasmina, Soler-Palacin, Pere, Sisinni, Luisa, Bueno, David, Riviere, Jacques, de Paz, Raquel, Sanchez-Zapardiel, Elena et al.
DOI: 10.1007/s10875-020-00961-w

Blog

News

The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.

During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.

The meeting was an opportunity to get to know projects from both institutions and to promote interaction between professionals.