About the VHIR
Here at the Vall d'Hebron Research Institute (VHIR) we promote biomedical research, innovation and teaching. Over 1,800 people are seeking to understand diseases today so the treatment can be improved tomorrow.
Research
We are working to understand diseases, to find out how they operate and to create better treatments for patients. Get to know about our groups and their lines of research.
People
People are the centre of the Vall d'Hebron Research Institute (VHIR). This is why we are bound by the principles of freedom of research, gender equality and professional attitudes that HRS4R promotes.
Clinical trials
Our work is not just basic or translational; we are leaders in clinical research. Enter and find about the clinical trials we are conducting and why we are a world reference in this field.
Progress
Our aim is to make the research carried out at the Vall d’Hebron Research Institute (VHIR) a driving force for transformation. How? By identifying new channels and solutions for the promotion of people's health and well-being.
Core facilities
We offer specialist support for researchers, internal and external alike, ranging from specific services to preparing complete projects. All this, from a perspective of quality and speed of response.
News
We offer you a gateway for staying up to date on everything going on at the Vall d’Hebron Research Institute (VHIR), from the latest news to future solidarity activities and initiatives that we are organising.
The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.
Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.
Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours
PMID: 35410925 Journal: BMJ Open Year: 2022 Reference: BMJ Open. 2022 Apr 11;12(4):e054690. doi: 10.1136/bmjopen-2021-054690. Impact factor: Publication type: Paper in international publication Authors: Ababneh, Hazim; Abantanga, Francis A; Abbas, Alzhraa Salah; Abdel-Maboud, Mohamed; Abdelhafeez, Hafeez; Abdelsalam, Sherief; Abdelwahab, Mohamed; Abdessamad, El Ouahabi; Abdul Qadir, Muskaan; Abdul-Mumin, Alhassan et al. DOI: 10.1136/bmjopen-2021-054690
PMID: NOPMID0100 Journal: Advances in Laboratory Medicine Year: 2022 Reference: Adv Lab Med / Av en Med Lab. 2022;3(3):263-271. doi:10.1515/almed-2022-0016 Impact factor: Publication type: Paper in national publication Authors: Barquin Del Pino , Raquel ; Benitez Carabante, Maria Isabel ; Casis Saenz, Ernesto; Castellote Bellés, Laura; Ferrer Costa, Roser; López Hellin, Joan; Martinez Sánchez, Luisa; Miarons Font , Marta; Paciucci Barzanti, Rosanna; Rodríguez Frias, Francisco et al. DOI: 10.1515/almed-2022-0016
PMID: 34865946 Journal: EUROPEAN JOURNAL OF CANCER Year: 2022 Reference: Eur J Cancer. 2022 Jan;160:206-214. doi: 10.1016/j.ejca.2021.10.031. Epub 2021 Dec 2. Impact factor: 9.162 Publication type: Paper in international publication Authors: Slater, Olga; Gains, Jennifer E; Kelsey, Anna M; De Corti, Federica; Zanetti, Ilaria; Coppadoro, Beatrice; Jorgensen, Mette; Gallego, Soledad; Orbach, Daniel H; Glosli, Heidi et al. DOI: 10.1016/j.ejca.2021.10.031
PMID: 34582098 Journal: PEDIATRIC BLOOD & CANCER Year: 2022 Reference: Pediatr Blood Cancer. 2022 Feb;69(2):e29376. doi: 10.1002/pbc.29376. Epub 2021 Sep 28. Impact factor: 3.167 Publication type: Paper in international publication Authors: Smeulders, Naima; Mudry, Peter; Zin, Angelica; Merks, Johannes H M; Slater, Olga; Alaggio, Rita; Gallego, Soledad; Coppadoro, Beatrice; Daragjati, Julia; Bisogno, Gianni et al. DOI: 10.1002/pbc.29376
PMID: 33620682 Journal: Clinical & Translational Oncology Year: 2021 Reference: Clin Transl Oncol. 2021 Aug;23(8):1529-1541. doi: 10.1007/s12094-021-02558-0. Epub 2021 Feb 23. Impact factor: Publication type: Paper in international publication Authors: Alvarez, R; Bautista, F; Colomer, R; de Alava, E; Garrido, P; Hladun, R; Lopez-Rios, F; Rojo, F et al. DOI: 10.1007/s12094-021-02558-0
PMID: 33613322 Journal: Frontiers in Physiology Year: 2021 Reference: Front Physiol. 2021 Feb 5;12:628236. doi: 10.3389/fphys.2021.628236. eCollection 2021. Impact factor: Publication type: Paper in international publication Authors: Beneitez, David; Blanco-Alvarez, Adoracion; de Pagter, Anne J; Del Orbe, Rafael; Diaz de Heredia, Cristina; Elting, Mariet; Harteveld, Cornelis L; Idrizovic, Amira; Kerkhoffs, Jean-Louis H; Koopmann, Tamara T et al. DOI: 10.3389/fphys.2021.628236
PMID: 32880696 Journal: EUROPEAN RADIOLOGY Year: 2021 Reference: Eur Radiol. 2021 Mar;31(3):1494-1504. doi: 10.1007/s00330-020-07182-0. Epub 2020 Sep 3. Impact factor: Publication type: Paper in international publication Authors: Beishuizen, Auke; Bruin, Marrie C A; de Keizer, Bart; de Lange, Charlotte; Elias, Sjoerd G; Enriquez, Goya; Granata, Claudio; Greer, Mary-Louise C; Kwee, Thomas C; Littooij, Annemieke S et al. DOI: 10.1007/s00330-020-07182-0
PMID: 33296531 Journal: EUROPEAN JOURNAL OF HAEMATOLOGY Year: 2021 Reference: Eur J Haematol. 2021 Mar;106(3):408-416. doi: 10.1111/ejh.13566. Epub 2021 Jan 4. Impact factor: Publication type: Paper in international publication Authors: Alonso, Laura; Belendez, Cristina; Benitez-Carabante, Maria Isabel; Cela, Elena; Diaz-de-Heredia, Cristina; Fuster, Jose Luis; Gonzalez-Vicent, Marta; Perez-Hurtado, Jose Maria; Torrent, Monserrat; Uria-Oficialdegui, Maria Luz et al. DOI: 10.1111/ejh.13566
PMID: 32013689 Journal: Journal of Laparoendoscopic & Advanced Surgical Techniques Year: 2020 Reference: J Laparoendosc Adv Surg Tech A. 2020 Apr;30(4):458-463. doi: 10.1089/lap.2019.0515. Epub 2020 Feb 3. Impact factor: Publication type: Paper in international publication Authors: Guillen, Gabriela; Lopez, Manuel; Lopez-Fernandez, Sergio; Martin-Gimenez, Marta Pilar; Molino, Jose Andres et al. DOI: 10.1089/lap.2019.0515
PMID: 32015347 Journal: Cell Death & Disease Year: 2020 Reference: Cell Death Dis. 2020 Feb 3;11(2):82. doi: 10.1038/s41419-020-2282-x. Impact factor: Publication type: Paper in international publication Authors: Badillos-Rodriguez, Raquel; Barneda-Zahonero, Bruna; Coccia, Elena; Comella, Joan X; Fernandez-Hernandez, Rita; Gari, Eloi; Lopez-Soriano, Joaquin; Moubarak, Rana S; Pascual, Marta; Perez-Garcia, M Jose et al. DOI: 10.1038/s41419-020-2282-x
PMID: 32007712 Journal: EUROPEAN JOURNAL OF CANCER Year: 2020 Reference: Eur J Cancer. 2020 Mar;127:123-129. doi: 10.1016/j.ejca.2019.12.021. Epub 2020 Jan 30. Impact factor: Publication type: Paper in international publication Authors: Alaggio, Rita; Bisogno, Gianni; Brennan, Bernadette; Casanova, Michela; Corradini, Nadege; De Salvo, Gian Luca; Ferrari, Andrea; Gallego, Soledad; Kelsey, Anna; Merks, Johannes H M et al. DOI: 10.1016/j.ejca.2019.12.021
PMID: 31738823 Journal: BLOOD Year: 2020 Reference: Blood. 2020 Jan 23;135(4):274-286. doi: 10.1182/blood.2019002699. Impact factor: Publication type: Paper in international publication Authors: Andion, Maitane; Andres, Mara; Astigarraga, Itziar; Azorin, Daniel; Balague, Olga; Barcena, Carmen; Campo, Elias; Celis, Veronica; Clot, Guillem; Dlouhy, Ivan et al. DOI: 10.1182/blood.2019002699
PMID: 30995915 Journal: Orphanet Journal of Rare Diseases Year: 2019 Reference: Orphanet J Rare Dis. 2019 Apr 17;14(1):82. doi: 10.1186/s13023-019-1046-0. Impact factor: 3.687 Publication type: Paper in international publication Authors: Arias-Salgado, Elena G, Galvez, Eva, Planas-Cerezales, Lurdes, Vallespin, Elena, Pintado-Berninches, Laura, Sastre, Leandro, Molina-Molina, Maria, Martinez, Pilar, Carrillo, Jaime, Iarriccio, Laura et al. DOI: 10.1186/s13023-019-1046-0
PMID: 30828868 Journal: EUROPEAN JOURNAL OF HAEMATOLOGY Year: 2019 Reference: Eur J Haematol. 2019 Jun;102(6):465-471. doi: 10.1111/ejh.13226. Epub 2019 Apr 10. Impact factor: 2.217 Publication type: Paper in international publication Authors: Heras, Inmaculada, Viguria, M, Batlle, M, Vazquez, L, Lopez, J, Solano, C, Gonzalez Vicent, M, Suarez-Lledo, M, Alonso, L, Garcia, E et al. DOI: 10.1111/ejh.13226
PMID: 30782268 Journal: Eurosurveillance Year: 2019 Reference: Euro Surveill. 2019 Feb;24(7). doi: 10.2807/1560-7917.ES.2019.24.7.1700857. Impact factor: 7.421 Publication type: Review in international publication Authors: Martinez-Gomez, Xavier, Curran, Adrian, Campins, Magda, Alemany, Laia, Rodrigo-Pendas, Jose Angel, Borruel, Natalia, Castellsague, Xavier, Diaz-de-Heredia, Cristina, Moraga-Llop, Fernando A, Del Pino, Marta et al. DOI: 10.2807/1560-7917.ES.2019.24.7.1700857
PMID: 30770954 Journal: CELLULAR AND MOLECULAR LIFE SCIENCES Year: 2019 Reference: Cell Mol Life Sci. 2019 Jun;76(11):2231-2243. doi: 10.1007/s00018-019-03041-4. Epub 2019 Feb 15. Impact factor: 7.014 Publication type: Paper in international publication Authors: Soriano, Aroa, Masanas, Marc, Boloix, Ariadna, Masia, Nuria, Paris-Coderch, Laia, Piskareva, Olga, Jimenez, Carlos, Henrich, Kai-Oliver, Roma, Josep, Westermann, Frank et al. DOI: 10.1007/s00018-019-03041-4
PMID: 27811020 Journal: BLOOD Year: 2017 Reference: Blood. 2017 Jan 26;129(4):525-532. doi: 10.1182/blood-2016-06-722249. Epub 2016 Nov 3. Impact factor: 13.164 Publication type: Paper in international publication Authors: Rocha, Vanderson, Cunha, Renato, Zago, Marco A, Querol, Sergio, Volt, Fernanda, Ruggeri, Annalisa, Sanz, Guillermo, Pouthier, Fabienne, Kogler, Gesine, Vicario, Jose L et al. DOI: 10.1182/blood-2016-06-722249
The association, once again, has shown its commitment to oncological research with a donation of €19,197 to the Cancer and Hematological Diseases Group for Children at VHIR.
The prestigious journal The Lancet has published the results of this study, which is the result of more than 20 years of pre-clinical research and 7 years of patient follow-up.
During the meeting, the role of the Vall d'Hebron Paediatric Research Hub in promoting research on children and adolescents was highlighted.
