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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Maria Oliveras Arenas

Maria Oliveras Arenas

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Pablo Velasco Puyó

Pablo Velasco Puyó

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Carlota Aguilera Ordoñez

Carlota Aguilera Ordoñez

Research technician
Childhood Cancer and Blood Disorders
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Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
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Marina Bonfill Ralló

Marina Bonfill Ralló

Research technician
Childhood Cancer and Blood Disorders
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Maria Oliveras Arenas

Maria Oliveras Arenas

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Pablo Velasco Puyó

Pablo Velasco Puyó

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Carlota Aguilera Ordoñez

Carlota Aguilera Ordoñez

Research technician
Childhood Cancer and Blood Disorders
Read more
Gabriela Guillén Burrieza

Gabriela Guillén Burrieza

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Juan Manuel López Oliva

Juan Manuel López Oliva

Research technician
Childhood Cancer and Blood Disorders
Read more
Marina Bonfill Ralló

Marina Bonfill Ralló

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

RealiseD: Comprehensive methodological and operational approach to clinical trials in rare and ultra-rare diseases

IP: M Mar Mañu Pereira
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 188587.5
Reference: REALISED
Duration: 01/01/2025 - 31/12/2029

Targeting chromatin remodelers for cancer therapy

IP: Miguel Segura Ginard
Collaborators: Maria Jose Pérez García, Marta Miera Maluenda, Adria Molero Valenzuela, Lucas Moreno Martín-Retortillo
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 150000
Reference: 2024 PROD 00054
Duration: 02/12/2024 - 01/06/2026

Development of a novel and potent strategy for blocking the Hedgehog pathway to treat pediatric sarcomas

IP: Josep Roma Castanyer
Collaborators: Guillem Pons Barcons, Raquel Hladun Alvaro, Lia Garcia Gilabert, Patricia Zarzosa Martinez, Lucas Moreno Martín-Retortillo
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 20000
Reference: 2024 LLAV 00024
Duration: 02/12/2024 - 01/06/2025

HemaFAIR: Fostering F.A.I.R. Data and Standards in Rare Hematological Diseases

IP: M Mar Mañu Pereira
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding: 221875
Reference: HEMAFAIR/EC/WIDERA-2023-ACCESS-02-01/2023/MAÑU
Duration: 01/06/2024 - 30/06/2027

Blog

News

The charitable initiative created in honor of Pol is supporting a research project aimed at identifying therapeutic targets to treat a rare type of leukemia.

The charitable initiative will allocate all funds to research on pediatric nervous system tumors carried out at the Vall d’Hebron Research Institute

The study, led by Dr. Lucas Moreno and University of Birmingham shows that the combined administration of chemotherapy and immunotherapy with the antibody dinutuximab beta achieves a better treatment response.