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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
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Judith Canto Santos

Judith Canto Santos

Research technician
Childhood Cancer and Blood Disorders
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Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
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Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Luz Elena Valderrama Orenday

Luz Elena Valderrama Orenday

Research technician
Childhood Cancer and Blood Disorders
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Jorge Fernández Fernández

Jorge Fernández Fernández

Research technician
Childhood Cancer and Blood Disorders
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Judith Canto Santos

Judith Canto Santos

Research technician
Childhood Cancer and Blood Disorders
Read more
Júlia Sansa Girona

Júlia Sansa Girona

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Khloud Abdo Soliman Elsharawy

Khloud Abdo Soliman Elsharawy

Postdoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Laura Romero Rodriguez

Laura Romero Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Luz Elena Valderrama Orenday

Luz Elena Valderrama Orenday

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

IMPACT- AML

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Sara Isabel Reidel , Daiana Natali Lopez
Funding agency: EUROPEAN COMMISSION
Funding: 253750
Reference: IMPACT-AML_HE--MISS-CANCER2022
Duration: 01/04/2023 - 31/03/2028

Grup de Recerca Emergent (GRE) Childood Cancer & Blood disorders

IP: Lucas Moreno Martín-Retortillo
Collaborators: Luís Gros Subias, Raquel Andreu Vilarroig, Andrea Vilaplana Blanes, Pablo Velasco Puyó, Laura Murillo Sanjuán, Maria Isabel Benitez Carabante, Aroa Soriano Fernández, Guillem Pons Barcons, Jose Miguel Lizcano De Vega, Maria Cristina Díaz de Heredia Rubio, Maria Luz Uría Oficialdegui, Grup de Recerca Emergent (GRE) Childood Cancer & Blood disorders, Miguel Segura Ginard, M Mar Mañu Pereira, Lorena Valero Arrese, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Anna Llort Sales, Raquel Hladun Alvaro, Carlota Aguilera Ordoñez, Adria Molero Valenzuela, Grup de Recerca Emergent (GRE) Childood Cancer & Blood disorders, Gabriela Guillén Burrieza, Laura Alonso Garcia, Idoia Bolinaga Ayala, Josep Roma Castanyer, Sergio Espinosa Gil, Elena Andretta, Claire Diot, Amira Idrizovic
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 60000
Reference: 2021 SGR 00638
Duration: 01/01/2022 - 30/06/2025

SYNTHEMA: Synthetic generation of hematological data over federated computing frameworks

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Sara Isabel Reidel , Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 435938
Reference: SYNTHEMA_HE-HLTH22_IND13
Duration: 01/12/2022 - 30/11/2026

Desarrollo de una nueva diana terapéutica con elevado potencial anti-oncogénico para los sarcomas infantiles: bloqueo farmacológico del co-receptor de Hedgehog CDO.

IP: Josep Roma Castanyer
Collaborators: -
Funding agency: Fundación Inocente Inocente
Funding: 90000
Reference: INOCENTE/RECERCA/2022/ROMA
Duration: 10/10/2022 - 30/09/2025

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Blog

News

The integration of Patient-Reported Outcome Measures (PROMs) will make it possible to incorporate patients' experiences and quality of life into research on sickle cell disease and other rare anaemias.

The Scientific Coordinator of ERN-EuroBloodNet will lead for one year the group that defines the common strategy of the European Reference Networks to improve care for rare and complex diseases.

Vall d’Hebron participates as a reference centre in Spain for early-phase clinical trials and coordinates the national ReALLNet network, promoting research into relapsed acute lymphoblastic leukemia.