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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Maria Gallego Rodriguez

Maria Gallego Rodriguez

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Maria Jesus Rodríguez Rodríguez

Maria Jesus Rodríguez Rodríguez

Research technician
Childhood Cancer and Blood Disorders
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Maria Luz Uría Oficialdegui

Maria Luz Uría Oficialdegui

Predoctoral researcher
Childhood Cancer and Blood Disorders
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María Paula Pérez Albert

María Paula Pérez Albert

Main researcher
Childhood Cancer and Blood Disorders
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María Victoria Cerezo Morales

María Victoria Cerezo Morales

Administration and Management
Childhood Cancer and Blood Disorders
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Marina Ortiz Palacios

Marina Ortiz Palacios

Childhood Cancer and Blood Disorders
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Maria Gallego Rodriguez

Maria Gallego Rodriguez

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Maria Jesus Rodríguez Rodríguez

Maria Jesus Rodríguez Rodríguez

Research technician
Childhood Cancer and Blood Disorders
Read more
Maria Luz Uría Oficialdegui

Maria Luz Uría Oficialdegui

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
María Paula Pérez Albert

María Paula Pérez Albert

Main researcher
Childhood Cancer and Blood Disorders
Read more
María Victoria Cerezo Morales

María Victoria Cerezo Morales

Administration and Management
Childhood Cancer and Blood Disorders
Read more
Marina Ortiz Palacios

Marina Ortiz Palacios

Childhood Cancer and Blood Disorders
Read more

Projects

ENABLING PERSONALIZED MEDICINE OF SICKLE CELL DISEASE PATIENTS BASED ON INTEGRATIVE DIAGNOSIS OF NEW GENERATION METHODOLOGIES

IP: M Mar Mañu Pereira
Collaborators: Pablo Velasco Puyó, Bárbara Tazón Vega, David Beneitez Pastor, Maria Cristina Díaz de Heredia Rubio, Adoración Blanco Alvarez, Thaïs Murciano Carrillo, Amira Idrizovic
Funding agency: Instituto de Salud Carlos III
Funding: 99220
Reference: PI20/01454
Duration: 01/01/2021 - 30/06/2025

ERICA - European Rare dIsease research Coordination and support Action

IP: M Mar Mañu Pereira
Collaborators: Claire Diot, Raquel Mosull del Campo
Funding agency: EUROPEAN COMMISSION
Funding: 105250
Reference: ERICA_H2020-SC1-BHC-2020
Duration: 01/03/2021 - 31/08/2025

GENOMED4ALL - Genomics and Personalized Medicine for all though Artificial Intelligence in Haematological Diseases

IP: M Mar Mañu Pereira
Collaborators: Reidel , Sara Isabel, Amira Idrizovic , Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 434000
Reference: GENOMED4ALL_H2020-SC1-FA-DTS-2018-20
Duration: 01/01/2021 - 30/06/2025

BEACON-BIO: deep biological characterisation and development of biomarkers for relapsed neuroblastoma

IP: Lucas Moreno Martín-Retortillo
Collaborators: Andrea Vilaplana Blanes, BEACON-BIO: deep biological characterisation and development of biomarkers for relapsed neuroblastoma
Funding agency: European Science Foundation
Funding: 104500
Reference: BEACON-BIO_FKC_2021
Duration: 01/01/2022 - 30/09/2025

Blog

News

The charitable initiative created in honor of Pol is supporting a research project aimed at identifying therapeutic targets to treat a rare type of leukemia.

The charitable initiative will allocate all funds to research on pediatric nervous system tumors carried out at the Vall d’Hebron Research Institute

The study, led by Dr. Lucas Moreno and University of Birmingham shows that the combined administration of chemotherapy and immunotherapy with the antibody dinutuximab beta achieves a better treatment response.