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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Marina Ortiz Palacios

Marina Ortiz Palacios

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
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Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
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Alba María Albert Robledo

Alba María Albert Robledo

Administration and Management
Childhood Cancer and Blood Disorders
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Amalia Varo Rodriguez

Amalia Varo Rodriguez

Senior researcher
Childhood Cancer and Blood Disorders
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Marina Ortiz Palacios

Marina Ortiz Palacios

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
Read more
Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
Read more
Alba María Albert Robledo

Alba María Albert Robledo

Administration and Management
Childhood Cancer and Blood Disorders
Read more
Amalia Varo Rodriguez

Amalia Varo Rodriguez

Senior researcher
Childhood Cancer and Blood Disorders
Read more

Projects

RealiseD: Comprehensive methodological and operational approach to clinical trials in rare and ultra-rare diseases

IP: M Mar Mañu Pereira
Collaborators: Francisco González Romero, Francisco González Romero, Francisco González Romero, Ángela Menárguez López, Ángela Menárguez López
Funding agency: EUROPEAN COMMISSION
Funding: 267500
Reference: REALISED
Duration: 01/01/2025 - 31/12/2029

Targeting chromatin remodelers for cancer therapy

IP: Miguel Segura Ginard
Collaborators: Maria Jose Pérez García, Marta Miera Maluenda, Adria Molero Valenzuela, Lucas Moreno Martín-Retortillo
Funding agency: Agència Gestió Ajuts Universitaris i de Recerca
Funding: 150000
Reference: 2024 PROD 00054
Duration: 02/12/2024 - 01/06/2026

HemaFAIR: Fostering F.A.I.R. Data and Standards in Rare Hematological Diseases

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Núria Torquet i Luna, Esther García Pagès
Funding agency: EUROPEAN COMMISSION
Funding: 221875
Reference: HEMAFAIR/EC/WIDERA-2023-ACCESS-02-01/2023/MAÑU
Duration: 01/06/2024 - 30/06/2027

ERDERA: European Rare Disease Research Alliance

IP: M Mar Mañu Pereira
Collaborators: Sara Isabel Reidel , Sara Isabel Reidel , Miguel Chillon Rodriguez, Esther García Pagès, Raquel Mosull del Campo, Raquel Mosull del Campo, Simon Schwartz Navarro, Agustín Arasanz Duque, Sandra Mancilla Zamora, Anna Collado Gimbert, Marc Miquel Moltó Abad, Ángela Menárguez López, Ángela Menárguez López, Ángela Menárguez López, Claire Diot
Funding agency: EUROPEAN COMMISSION
Funding: 771525
Reference: ERDERA_MAÑU_EC_HLTH2023-DISEASE-07-01/2023
Duration: 01/09/2024 - 31/08/2031

Blog

News

The projects, selected under the 2026 Health Research and CaixaImpulse Health Innovation calls, address topics ranging from new therapies for childhood neurological disorders and Parkinson’s disease to the treatment of mitochondrial diseases and cancer.

A new publication describes the creation of this initiative, which has facilitated access to genomic studies for more than 900 pediatric patients with cancer from across Spain.

The families of the professionals had the opportunity to visit the facilities and discover how we work at the institution.