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Childhood Cancer and Blood Disorders

The research group is focused on finding new molecular therapeutic targets and biomarkers based on knowledge of the biology of paediatric tumours, leukemias and hematologic diseases. The experience of the group in recent years has permitted the identification of new molecular targets that are very close to the clinical phase. In this stage, we have consolidated collaborations with the biotechnological industry in order to develop small molecules able to inhibit pro-oncogenic processes such as invasion or proliferation, with the aim of providing patients with innovative and more specific biological evidence-based therapies.

Another line of research is based on the study of liquid biopsy to develop a system based on NGS to monitor the probability of relapses.

Furthermore, we have implemented a personalized medicine program to guide the management of patients based on the molecular alterations of their tumours

Team

Maria Cristina Díaz de Heredia Rubio

Maria Cristina Díaz de Heredia Rubio

Childhood Cancer and Blood Disorders
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Marina Ortiz Palacios

Marina Ortiz Palacios

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
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Adrian Avellaneda Rodriguez

Adrian Avellaneda Rodriguez

Research technician
Childhood Cancer and Blood Disorders
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Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
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Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
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Maria Cristina Díaz de Heredia Rubio

Maria Cristina Díaz de Heredia Rubio

Childhood Cancer and Blood Disorders
Read more
Marina Ortiz Palacios

Marina Ortiz Palacios

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Raquel Hladun Alvaro

Raquel Hladun Alvaro

Predoctoral researcher
Childhood Cancer and Blood Disorders
Read more
Adrian Avellaneda Rodriguez

Adrian Avellaneda Rodriguez

Research technician
Childhood Cancer and Blood Disorders
Read more
Aina Llenas Bladé

Aina Llenas Bladé

Research technician
Childhood Cancer and Blood Disorders
Read more
Ajla Idrizovic

Ajla Idrizovic

Research technician
Childhood Cancer and Blood Disorders
Read more

Projects

ERN-EuroBloodNet (European Reference Network on Rare Hematological Diseases)

IP: M Mar Mañu Pereira
Collaborators: Raquel Mosull del Campo, Sara Isabel Reidel
Funding agency: EUROPEAN COMMISSION
Funding: 1569581.5
Reference: EUROBLOODNET-ERN_EU4H2023
Duration: 01/10/2023 - 30/09/2027

Seniority Josep Romà 2024

IP: Josep Roma Castanyer
Collaborators: -
Funding agency: VHIR
Funding: 296955
Reference: VHIR-SEN-2023-002
Duration: 01/05/2024 - 30/04/2029

La interacción entre el error innato de la inmunidad y los trastornos sanguíneos: desentrañando los defectos inmunitarios detrás de las enfermedades hematológicas comunes

IP: Pere Soler Palacín
Collaborators: Laura Batlle Masó, Maria Cristina Díaz de Heredia Rubio, Roger Colobran Oriol, Thaïs Murciano Carrillo, Constantino Sábado Álvarez, Miriam Gonzalez Amores, Janire Perurena Prieto, Andrea Martín Nalda, Lucas Moreno Martín-Retortillo, Jacques Gabriel Rivière
Funding agency: Instituto de Salud Carlos III
Funding: 179993.75
Reference: AC23_2/00033
Duration: 01/01/2024 - 31/12/2026

HELIOS: Haemoglobinopathies in European Liaison of Medicine and Science

IP: M Mar Mañu Pereira
Collaborators: -
Funding agency: EUROPEAN COMMISSION
Funding:
Reference: EC / COST-ACTION / 2022 / MAÑU
Duration: 20/09/2023 - 19/09/2027

Blog

News

The initiative will enable young people aged 12 to 18 to collaborate with campus researchers in the design, development and communication of scientific projects, placing patients and families at the centre of the research process.

The REACH5 study confirms that the efficacy and safety results observed in previous studies are maintained after three years of follow-up.

In-depth knowledge of tumours helps identify specific alterations and enables the provision of targeted therapies for each patient.